Peripheral Tolerance and Memory

Peripheral tolerance is the second branch of immunological tolerance that ensures that self reactive B and T cells do not result in autoimmunity. Here is the latest research on peripheral tolerance and memory.

August 21, 2020
Open Access

Haploidentical mixed chimerism cures autoimmunity in established type 1 diabetic mice

The Journal of Clinical Investigation
Yuqing LiuDefu Zeng
March 11, 2020
Review
Open Access

The Impact of Dietary Components on Regulatory T Cells and Disease

Frontiers in Immunology
Rebeca Arroyo HorneroMarkus Kleinewietfeld
July 17, 2020
Review
Open Access

Exploring the Origin and Antigenic Specificity of Maternal Regulatory T Cells in Pregnancy

Frontiers in Immunology
Soo Hyun AhnMargaret G Petroff
August 11, 2020
Open Access

Altered Regulatory B Cell Subsets in Children with Type 1 Diabetes Mellitus

Journal of Immunology Research
Mohamed A El-MokhtarAmira M Shalaby
September 20, 2020
Review
Open Access

Revisiting the PD-1 pathway

Science Advances
Nikolaos PatsoukisVassiliki A Boussiotis
July 28, 2020

Regulatory T cells: Master thieves of the immune system

Cellular Immunology
Billur Akkaya, Ethan M Shevach
April 7, 2020
Open Access

Rapid expansion of Treg cells protects from collateral colitis following a viral trigger

Nature Communications
Michelle SchorerNicole Joller
October 2, 2020

Tolerance mechanisms in allergen immunotherapy

Current Opinion in Allergy and Clinical Immunology
Zeynep Celebi SözenerCezmi Akdis
April 24, 2020
Review

B Cell Development and Maturation

Advances in Experimental Medicine and Biology
Ying WangJi-Yang Wang
October 13, 2020
Open Access

Increased Protein Stability and Interleukin-2 Production of a LATG131D Variant With Possible Implications for T Cell Anergy

Frontiers in Cell and Developmental Biology
Mikel M Arbulo-EchevarriaEnrique Aguado
January 31, 2020
Review
Open Access

Tolerating Factor VIII: Recent Progress

Frontiers in Immunology
Sebastien Lacroix-DesmazesKathleen P Pratt
August 4, 2020
Review
Open Access

Paradoxical role of Breg-inducing cytokines in autoimmune diseases

Journal of Translational Autoimmunity
Fatin N Mohd JayaMarcella Franquesa
August 14, 2020
Open Access

Human Lymph Node Stromal Cells Have the Machinery to Regulate Peripheral Tolerance during Health and Rheumatoid Arthritis

International Journal of Molecular Sciences
Janine S HähnleinLisa G M van Baarsen
October 6, 2020
Open Access

CD226 Deletion Reduces Type 1 Diabetes in the NOD Mouse by Impairing Thymocyte Development and Peripheral T Cell Activation

Frontiers in Immunology
Melanie R ShapiroTodd M Brusko
January 24, 2020

Contribution of Th2-like Treg cells to the pathogenesis of Takayasu's arteritis

Clinical and Experimental Rheumatology
Na GaoLi Li Pan

Sign up to follow this feed and discover related papers.

Related Feeds

Antibodies: Agglutination

Antibody-mediated agglutination is the clumping of cells in the presence of antibody, which binds multiple cells together. This enhances the clearance of pathogens. Find the latest research on antibody-mediated agglutination here.

Antibodies: Complement Activation

The complement system can be activated by antigen-associated antibody. In the classical pathway of complement activation, C1q, C4b, and C3b are all able to bind to the Fc portion of IgG or IgM. Find the latest research on antibodies and complement activation here.

Antibody Development

Development of antibodies require integration of knowledge with respect to target antigen properties, antibody design criteria such as affinity, isotype selection, Fc domain engineering, and antibody cross-reactivity across species from the early stages of antibody development. Here is the latest research.


Antibody Specificity

Antibodies produced by B cells are highly specific for antigen as a result of random gene recombination and somatic hypermutation and affinity maturation. As the main effector of the humoral immune system, antibodies can neutralize foreign cells. Find the latest research on antibody specificity here.

Antibody synthesis

Antibodies have various functions including neutralization of pathogens, tumor targeting, as well as its utility in biomedical research. Here is the latest research on antibody synthesis.

Antibody-Dependent Cell Cytotoxicity

Antibody-dependent cellular toxicity refers to the lysis of a target cell by a non-sensitized effector cell of the immune system as a result of antibodies binding to the target cell membrane and engaging the Fc receptors on the immune effector cells. Find the latest research on antibody-dependent cellular toxicity here.

Antibody-Dependent Enhancement

Antibody-dependent enhancement of viral infection is the entry of virus into host cells mediated by antiviral antibodies interacting with Fc or complement receptors. This has been most extensively observed with the dengue virus. Find the latest research on antibody-dependent enhancement here.

Antigenic Modulation

Antigenic modulation occurs when an antibody cross-links antigens on a cell surface, causing the antigens to become internalized. This can lead to therapeutic failure of monoclonal antibodies as the expression of the antigen becomes decreased on target cells. Find the latest research on antigenic modulation here.

B cell Activation

B cell activation is initiated by the ligation of the B cell receptor with antigen and ultimately results in the production of protective antibodies against potentially pathogenic invaders. Here is the latest research.

B cell Differentiation

Depending on the signal received through the B cell receptor and other receptors, B cells differentiate into follicular or marginal zone B cells. Here is the latest research pertaining to this differentiation process.

© 2020 Meta ULC. All rights reserved
/feed-previews/peripheral-tolerance-and-memory/1a4b0949-08ef-4e8c-b944-15b6f737e1aa