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Pharmacogenetics & Pharmacogenomics
Xie et al, PLOS Computational BiologyPharmacogenetics and pharmacogenomics (pgx) are rapidly growing fields that aim to elucidate the genetic basis for the interindividual differences in drug response. Here is the latest research on pharmacogenetics and pharmacogenomics.
Top 20 most recent papers
Identification of genetic polymorphisms modulating nausea and vomiting in two series of opioid-treated cancer patients
Scientific ReportsJanuary 19, 2020
Francesca ColomboAugusto Tommaso Caraceni
3
Cost-Effectiveness of RAS Genetic Testing Strategies in Patients With Metastatic Colorectal Cancer: A Systematic Review
Value in Health : the Journal of the International Society for Pharmacoeconomics and Outcomes ResearchJanuary 19, 2020
Brigid UnimPaolo Villari
3
10
Chromosome arm aneuploidies shape tumour evolution and drug response
Nature CommunicationsJanuary 25, 2020
Ankit ShuklaPascal H G Duijf
19
Impact of SLCO1B1 genetic variation on rosuvastatin systemic exposure in pediatric hypercholesterolemia
Clinical and Translational ScienceJanuary 26, 2020
Jonathan B WagnerJ Steven Leeder
Scientific and Regulatory Considerations for an Ontogeny Knowledge Base for Pediatric Clinical Pharmacology
Clinical Pharmacology and TherapeuticsJanuary 27, 2020
Gilbert J BurckartIssam Zineh
Pharmacogenetics and pharmacokinetics modeling of unexpected and extremely severe toxicities after sorafenib intake
PharmacogenomicsJanuary 23, 2020
Hai le BaSébastien Salas
1
MID3: Mission Impossible or Model-Informed Drug Discovery and Development? Point-Counterpoint Discussions on Key Challenges
Clinical Pharmacology and TherapeuticsJanuary 20, 2020
Sriram KrishnaswamiSandra A G Visser
3
The effect of orally administered dronabinol on optic nerve head blood flow in healthy subjects- a randomized clinical trial
Clinical Pharmacology and TherapeuticsJanuary 25, 2020
Nikolaus HommerDoreen Schmidl
AITL: Adversarial Inductive Transfer Learning with input and output space adaptation for pharmacogenomics
bioRxivJanuary 25, 2020
Hossein Sharifi NoghabiMartin Ester
Fatal liver failure after therapeutic doses of paracetamol in a patient with Duchenne muscular dystrophy and atypical pharmacogenetic profile of drug-metabolizing enzymes
Basic & Clinical Pharmacology & ToxicologyJanuary 25, 2020
Yvonne Elisabeth LaoKnut Erik Hovda
Nephrotoxicity in a Patient With Inadequate Pain Control: Potential Role of Pharmacogenetic Testing for Cytochrome P450 2D6 and Apolipoprotein L1
Frontiers in PharmacologyJanuary 24, 2020
Emma M TillmanMichael T Eadon
Systematic Review and Meta-Analysis of the Moderating Effect of rs1799971 in OPRM1, the Mu-opioid Receptor Gene, on Response to Naltrexone Treatment of Alcohol Use Disorder
AddictionJanuary 22, 2020
Emily E HartwellHenry R Kranzler
2
Alternative Splicing in the Nuclear Receptor Superfamily Redirects Human Metabolic Homeostasis
Drug Metabolism and Disposition : the Biological Fate of ChemicalsJanuary 26, 2020
Andrew J AnnaloraPatrick L Iversen
2
"In-House" Data on the Outside - A Mobile Health Approach
Clinical Pharmacology and TherapeuticsJanuary 20, 2020
Qinlei HuangS Aubrey Stoch
19
Data Integrity in Global Clinical Trials: Discussions from Joint US FDA and MHRA UK Good Clinical Practice Workshop
Clinical Pharmacology and TherapeuticsJanuary 21, 2020
Ni A KhinStephen Vinter
Pharmacokinetics and pharmacodynamics of intensive anti-tuberculosis treatment of tuberculous meningitis
Clinical Pharmacology and TherapeuticsJanuary 21, 2020
Junjie DingJoel Tarning
11
Assessment of pharmacogenomic SLCO1B1 assay for prediction of neuromuscular pain in type 2 diabetes mellitus and cardiovascular patients: preliminary results
European Review for Medical and Pharmacological SciencesJanuary 21, 2020
A LicitoD De Lucia
Development of a System for Post-marketing Population Pharmacokinetic and Pharmacodynamic Studies using Real-World Data from Electronic Health Records
Clinical Pharmacology and TherapeuticsJanuary 21, 2020
Leena ChoiSara L Van Driest
2
Cost-Effectiveness of Multigene Pharmacogenetic Testing in Patients With Acute Coronary Syndrome After Percutaneous Coronary Intervention
Value in Health : the Journal of the International Society for Pharmacoeconomics and Outcomes ResearchJanuary 19, 2020
Olivia M DongTim Wiltshire
4
1
Open Models for Clinical Pharmacology
Clinical Pharmacology and TherapeuticsJanuary 27, 2020
Daniel C Kirouac