PI3K/AKT/mTOR Pathway

The PI3K/AKT/mTOR signal transduction pathway is crucial for cell cycle, thus directly regulates cell proliferation, longevity, and cancer. Here is the latest research on this intracellular signaling pathway.

August 11, 2020

HER2 in Colorectal Carcinoma: Are We There yet?

Surgical Pathology Clinics
Jonathan A Nowak
July 14, 2020

Precision Therapy for the Treatment of Primary Immunodysregulatory Diseases

Immunology and Allergy Clinics of North America
Deepak ChellapandianJennifer W Leiding
July 2, 2020
Open Access

BDH2 triggers ROS-induced cell death and autophagy by promoting Nrf2 ubiquitination in gastric cancer

Journal of Experimental & Clinical Cancer Research : CR
Jia-Zhou LiuWan-Jiang Xue
July 17, 2020
Open Access

Phosphatidylinositol-3 kinase activity controls survival and stemness of zebrafish hematopoietic stem/progenitor cells

BioRxiv : the Preprint Server for Biology
S. Blokzijl-FrankeJeroen den Hertog
July 3, 2020

The protective effect of decoction of Rehmanniae via PI3K/Akt/mTOR pathway in MPP+ -induced Parkinson's disease model cells

Journal of Receptor and Signal Transduction Research
Dajing Jiang, Yang Peng
July 15, 2020
Case Report
Open Access

Rheumatoid Arthritis and CLOVES Syndrome: A Tricky Diagnosis

Laura DamianRomana Vulturar
July 7, 2020

Curcumin downregulates the PI3K-AKT-mTOR pathway and inhibits growth and progression in head and neck cancer cells

Phytotherapy Research : PTR
Gabriel Alvares BorgesEliete Neves Silva Guerra
July 11, 2020
Open Access

The effects of mutant Ras proteins on the cell signalome

Cancer Metastasis Reviews
Tamás TakácsVirag Vas
August 11, 2020
Open Access

Shenzhiling Oral Liquid Protects STZ-Injured Oligodendrocyte through PI3K/Akt-mTOR Pathway

Evidence-based Complementary and Alternative Medicine : ECAM
Zhenhong LiuPengwen Wang
July 8, 2020
Open Access

The PI3K-AKT-mTOR Pathway and Prostate Cancer: At the Crossroads of AR, MAPK, and WNT Signaling

International Journal of Molecular Sciences
Boris Y ShorningHelen B Pearson

Sign up to follow this feed and discover related papers.

Related Feeds

Apoptosis in Cancer

Apoptosis is an important mechanism in cancer. By evading apoptosis, tumors can continue to grow without regulation and metastasize systemically. Many therapies are evaluating the use of pro-apoptotic activation to eliminate cancer growth. Here is the latest research on apoptosis in cancer.

Autophagy & Metabolism

Autophagy preserves the health of cells and tissues by replacing outdated and damaged cellular components with fresh ones. In starvation, it provides an internal source of nutrients for energy generation and, thus, survival. A powerful promoter of metabolic homeostasis at both the cellular and whole-animal level, autophagy prevents degenerative diseases. It does have a downside, however--cancer cells exploit it to survive in nutrient-poor tumors.

Autophagy: Cancer & Parkinson

Autophagy leads to degradation of damaged proteins and organelles by the lysosome. Impaired autophagy has been implicated in several diseases. Here is the role of autophagy in cancer and Parkinson’s.

Biophysics of Adhesion

Alterations in cell adhesion can disrupt important cellular processes and lead to a variety of diseases, including cancer and arthritis. It is also essential for infectious organisms, such as bacteria or viruses, to cause diseases. Understanding the biophysics of cell adhesion can help understand these diseases. Discover the latest research on the biophysics of adhesion here.

Cancer Biology: Molecular Imaging

Molecular imaging enables noninvasive imaging of key molecules that are crucial to tumor biology. Discover the latest research in molecular imaging in cancer biology in this feed.

Cancer Imaging

Imaging techniques, including CT and MR, have become essential to tumor detection, diagnosis, and monitoring. Here is the latest research on cancer imaging.

Cancer Metabolism

In order for cancer cells to maintain rapid, uncontrolled cell proliferation, they must acquire a source of energy. Cancer cells acquire metabolic energy from their surrounding environment and utilize the host cell nutrients to do so. Here is the latest research on cancer metabolism.

Cell Migration in Cancer and Metastasis

Migration of cancer cells into surrounding tissue and the vasculature is an initial step in tumor metastasis. Discover the latest research on cell migration in cancer and metastasis here.

Cell Signaling by Tyrosine Kinases

Receptor tyrosine kinases (RTKs) are the high-affinity cell surface receptors for many polypeptide growth factors, cytokines, and hormones. RTKs have been shown not only to be key regulators of normal cellular processes but also to have a critical role in the development and progression of many types of cancer. Discover the latest research on cell signaling and RTK here.

Circadian Clock & Cancer

Circadian rhythms are natural, internal processes that regulate the sleep-wake cycle. Chronic disruptions in circadian rhythms have been associated with the development of a variety of diseases including cancer. Here is the latest research on circadian rhythms and cancer.

© 2020 Meta ULC. All rights reserved