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Pioneer Factors (Keystone)

Pioneer Factors (Keystone) diagram by undefined

Pioneer factors are a class of transcription factors that possess the ability to bind to compact chromatin. This can lead to the recruitment of other proteins that regulate transcription. Discover the latest research on pioneer factors here.

Top 20 most recent papers
Proceedings of the National Academy of Sciences of the United States of America

FOXA1 upregulation promotes enhancer and transcriptional reprogramming in endocrine-resistant breast cancer

Proceedings of the National Academy of Sciences of the United States of AmericaDecember 13, 2019
Xiaoyong FuRachel Schiff
7
3
Cancer Cell

The Leukemogenic TCF3-HLF Complex Rewires Enhancers Driving Cellular Identity and Self-Renewal Conferring EP300 Vulnerability

Cancer CellNovember 19, 2019
Yun HuangJean-Pierre Bourquin
13
17
5
bioRxiv

Odd-paired is a late-acting pioneer factor coordinating with Zelda to broadly regulate gene expression in early embryos

bioRxivNovember 23, 2019
Theodora KoromilaAngelike Stathopoulos
25
Cell Stem Cell

Circadian Entrainment Triggers Maturation of Human In Vitro Islets

Cell Stem CellDecember 17, 2019
Juan R Alvarez-DominguezDouglas A Melton
119
1
Molecular Psychiatry

CHIMGEN: a Chinese imaging genetics cohort to enhance cross-ethnic and cross-geographic brain research

Molecular PsychiatryDecember 13, 2019
Qiang XuCHIMGEN Consortium
40
1
bioRxiv

Chromatin remodeling in bovine embryos indicates species-specific regulation of genome activation

bioRxivDecember 13, 2019
Michelle M HalsteadPablo J Ross
10
bioRxiv

Zygotic pioneer factor activity of Odd-paired/Zic is necessary for establishing the Drosophila Segmentation Network

bioRxivNovember 22, 2019
Isabella V SoluriShelby A Blythe
38
Genes & Development

Structural basis for distinct roles of SMAD2 and SMAD3 in FOXH1 pioneer-directed TGF-β signaling

Genes & DevelopmentOctober 5, 2019
Eric AragónJoan Massagué
16
4
16
Pharmacopsychiatry

From the Origins of Pharmacogenetics to First Applications in Psychiatry

PharmacopsychiatrySeptember 24, 2019
Daniel J Müller, Zoe Rizhanovsky
1
1
2
F1000Research

LEAFY COTYLEDONs : old genes with new roles beyond seed development

F1000ResearchJanuary 17, 2020
De Niu, Yuehui He
2
ELife

Dynamic regulation of chromatin accessibility by pluripotency transcription factors across the cell cycle

ELifeDecember 4, 2019
Elias T FrimanDavid M Suter
61
Cancer Research

MUC1-C Activates the NuRD Complex to Drive Dedifferentiation of Triple-Negative Breast Cancer Cells

Cancer ResearchSeptember 15, 2019
Tsuyoshi HataDonald Kufe
4
7
Computational and Structural Biotechnology Journal

The spatial binding model of the pioneer factor Oct4 with its target genes during cell reprogramming

Computational and Structural Biotechnology JournalJanuary 11, 2020
Hanshuang LiYongchun Zuo
Clinical Cancer Research : an Official Journal of the American Association for Cancer Research

Racial Differences in the Association between Luminal Master Regulator Gene Expression Levels and Breast Cancer Survival

Clinical Cancer Research : an Official Journal of the American Association for Cancer ResearchJanuary 9, 2020
Jung S ByunKevin Gardner
10
International Journal of Environmental Research and Public Health

Mechanism Underlying Flow Velocity and Its Corresponding Influence on the Growth of Euglena gracilis , a Dominant Bloom Species in Reservoirs

International Journal of Environmental Research and Public HealthNovember 27, 2019
Yi TanRuidong An
BMC Health Services Research

How to develop a sustainable telemedicine service? A Pediatric Telecardiology Service 20 years on - an exploratory study

BMC Health Services ResearchSeptember 25, 2019
Mélanie Raimundo MaiaLuís Velez Lapão
9
12
bioRxiv

HOX13-dependent chromatin accessibility modulates the target repertoires of the HOX factors

bioRxivOctober 2, 2019
Ines DesanlisMarie Kmita
44
9
bioRxiv

Establishment of chromatin accessibility by the conserved transcription factor Grainy head is developmentally regulated

bioRxivOctober 8, 2019
Markus NevilMelissa M Harrison
16
8
Seminars in Immunology

Epigenetic and transcriptional mechanisms for the regulation of IL-10

Seminars in ImmunologyNovember 4, 2019
Huiyuan Zhang, Vijay Kuchroo
1
4
Cell Reports

Meta-analysis of Chromatin Programming by Steroid Receptors

Cell ReportsSeptember 26, 2019
Ville PaakinahoGordon L Hager
18
22

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