Feed Preview

Fast Growing

Pioneer Factors (Keystone)

Pioneer Factors (Keystone) diagram by undefined

Pioneer factors are a class of transcription factors that possess the ability to bind to compact chromatin. This can lead to the recruitment of other proteins that regulate transcription. Discover the latest research on pioneer factors here.

Top 20 most recent papers
Proceedings of the National Academy of Sciences of the United States of America

FOXA1 upregulation promotes enhancer and transcriptional reprogramming in endocrine-resistant breast cancer

Proceedings of the National Academy of Sciences of the United States of AmericaDecember 13, 2019
Xiaoyong FuRachel Schiff
Cancer Cell

The Leukemogenic TCF3-HLF Complex Rewires Enhancers Driving Cellular Identity and Self-Renewal Conferring EP300 Vulnerability

Cancer CellNovember 19, 2019
Yun HuangJean-Pierre Bourquin

Odd-paired is a late-acting pioneer factor coordinating with Zelda to broadly regulate gene expression in early embryos

bioRxivNovember 23, 2019
Theodora KoromilaAngelike Stathopoulos
Cell Stem Cell

Circadian Entrainment Triggers Maturation of Human In Vitro Islets

Cell Stem CellDecember 17, 2019
Juan R Alvarez-DominguezDouglas A Melton
Molecular Psychiatry

CHIMGEN: a Chinese imaging genetics cohort to enhance cross-ethnic and cross-geographic brain research

Molecular PsychiatryDecember 13, 2019
Qiang XuCHIMGEN Consortium

Chromatin remodeling in bovine embryos indicates species-specific regulation of genome activation

bioRxivDecember 13, 2019
Michelle M HalsteadPablo J Ross

Zygotic pioneer factor activity of Odd-paired/Zic is necessary for establishing the Drosophila Segmentation Network

bioRxivNovember 22, 2019
Isabella V SoluriShelby A Blythe
Genes & Development

Structural basis for distinct roles of SMAD2 and SMAD3 in FOXH1 pioneer-directed TGF-β signaling

Genes & DevelopmentOctober 5, 2019
Eric AragónJoan Massagué

From the Origins of Pharmacogenetics to First Applications in Psychiatry

PharmacopsychiatrySeptember 24, 2019
Daniel J Müller, Zoe Rizhanovsky

LEAFY COTYLEDONs : old genes with new roles beyond seed development

F1000ResearchJanuary 17, 2020
De Niu, Yuehui He

Dynamic regulation of chromatin accessibility by pluripotency transcription factors across the cell cycle

ELifeDecember 4, 2019
Elias T FrimanDavid M Suter
Cancer Research

MUC1-C Activates the NuRD Complex to Drive Dedifferentiation of Triple-Negative Breast Cancer Cells

Cancer ResearchSeptember 15, 2019
Tsuyoshi HataDonald Kufe
Computational and Structural Biotechnology Journal

The spatial binding model of the pioneer factor Oct4 with its target genes during cell reprogramming

Computational and Structural Biotechnology JournalJanuary 11, 2020
Hanshuang LiYongchun Zuo
Clinical Cancer Research : an Official Journal of the American Association for Cancer Research

Racial Differences in the Association between Luminal Master Regulator Gene Expression Levels and Breast Cancer Survival

Clinical Cancer Research : an Official Journal of the American Association for Cancer ResearchJanuary 9, 2020
Jung S ByunKevin Gardner
International Journal of Environmental Research and Public Health

Mechanism Underlying Flow Velocity and Its Corresponding Influence on the Growth of Euglena gracilis , a Dominant Bloom Species in Reservoirs

International Journal of Environmental Research and Public HealthNovember 27, 2019
Yi TanRuidong An
BMC Health Services Research

How to develop a sustainable telemedicine service? A Pediatric Telecardiology Service 20 years on - an exploratory study

BMC Health Services ResearchSeptember 25, 2019
Mélanie Raimundo MaiaLuís Velez Lapão

HOX13-dependent chromatin accessibility modulates the target repertoires of the HOX factors

bioRxivOctober 2, 2019
Ines DesanlisMarie Kmita

Establishment of chromatin accessibility by the conserved transcription factor Grainy head is developmentally regulated

bioRxivOctober 8, 2019
Markus NevilMelissa M Harrison
Seminars in Immunology

Epigenetic and transcriptional mechanisms for the regulation of IL-10

Seminars in ImmunologyNovember 4, 2019
Huiyuan Zhang, Vijay Kuchroo
Cell Reports

Meta-analysis of Chromatin Programming by Steroid Receptors

Cell ReportsSeptember 26, 2019
Ville PaakinahoGordon L Hager

See more papers from this feed

Related Feeds

Aging Genetics (Keystone)

This feed focuses on aging epidemiology and genetic, epigenetic, and proteomic aspects underlying aging, as well as aging- associated biomarkers. Here the latest research in this domain.

Bivalency & Gene Expression (Keystone)

Bivalent chromatin are segments of DNA, bound to histone proteins, that have both repressing and activating epigenetic regulators in the same region. Here is the latest research on bivalent chromatin and gene expression.

Cell Aging (Keystone)

This feed focuses on cellular aging with emphasis on the mitochondria, autophagy, and metabolic processes associated with aging and longevity. Here is the latest research on cell aging.

Cell Signaling & Cancer Epigenetics (Keystone)

Epigenetic changes are present and dysregulated in many cancers, including DNA methylation, non-coding RNA segments and post-translational protein modifications. This feed covers the latest research on signaling and epigenetics in cell growth and cancer.

ChIP-Seq (Keystone)

Chromatin Immunoprecipitation followed by sequencing (ChIP-seq) is a genome-wide technique used to map histone marks and protein binding (i.e. transcription factors) on chromatin. This can reveal insight into the regulation and dynamics of gene expression. Discover the latest research on ChIP-seq here.

Chromatin Regulation and Circadian Clocks (Keystone)

The circadian clock plays an important role in regulating transcriptional dynamics through changes in chromatin folding and remodelling. Discover the latest research on chromatin regulation and circadian clocks here.

Chromatin Regulators: Differentiation (Keystone)

Chromatin regulators affect gene expression by influencing the access of proteins such as transcription factors to DNA. Here is the latest research on the role of chromatin regulating proteins in cellular differentiation.

Chromatin Remodeling (Keystone)

Chromatin remodeling is essential for regulation of gene expression, DNA replication, as well as DNA repair. Here is the latest research on chromatin remodeling complexes and mechanisms underlying this process.

Cryogenic Electron Microscopy (Keystone)

Cryogenic electron microscopy (Cryo-EM) uses a specific technique to allow for the visualization of macromolecules and their assemblies at a near-atomic resolution. Discover the latest research on Cryo-EM here.

DNA Methylation (Keystone)

DNA methylation is an epigenetic mechanism of gene regulation, and dysregulation of DNA methylation has been associated with tumorigenesis. Discover the latest research on DNA methylation here.

© 2020 Meta ULC. All rights reserved