Poly(ADP-Ribose) Polymerases

Poly(ADP-Ribose) Polymerase (PARP) is an enzyme with several functions, including cell differentiation, proliferation, and DNA damage repair. Here is the latest research on PARP.

October 6, 2020
Review

Clinical assays for assessment of homologous recombination DNA repair deficiency

Gynecologic Oncology
Elizabeth H StoverJoyce F Liu
October 8, 2020
Open Access

TGFβR-SMAD3 Signaling Induces Resistance to PARP Inhibitors in the Bone Marrow Microenvironment

Cell Reports
Bac Viet LeTomasz Skorski
October 12, 2020
Review

Redox-Dependent Regulation of Satellite Cells Following Aseptic Muscle Trauma: Implications for Sports Performance and Nutrition

Free Radical Biology & Medicine
Konstantinos PapanikolaouIoannis G Fatouros
October 11, 2020
Open Access

Overcoming resistance to PARP inhibitor in epithelial ovarian cancer, are we ready?

EBioMedicine
Isabelle Ray-CoquardOlivier Tredan
October 10, 2020

Inhibition of poly(ADP-ribose) polymerase induces synthetic lethality in BRIP1 deficient ovarian epithelial cells

Gynecologic Oncology
Marcia A CicconeKevin J McDonnell
October 12, 2020
Open Access

Targeting DNA Damage Response and Replication Stress in Pancreatic Cancer

Gastroenterology
Stephan B DreyerDavid K Chang
October 9, 2020

Targeting MALAT1 induces DNA damage and sensitize non-small cell lung cancer cells to cisplatin by repressing BRCA1

Cancer Chemotherapy and Pharmacology
Jinghua HuangDongchun Jin
October 7, 2020

Rational combination therapy for hepatocellular carcinoma with PARP1 and DNA-PK inhibitors

Proceedings of the National Academy of Sciences of the United States of America
Chen WangZhiyong Mao
October 14, 2020
Open Access

Cyclosporin A protects JEG-3 cells against oxidative stress-induced apoptosis by inhibiting the p53 and JNK/p38 signaling pathways

Reproductive Biology and Endocrinology : RB&E
Bin HeChuan Ling Tang

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