Prion Disease: Diagnostic Strategies

Prion diseases are fatal neurodegenerative and infectious disorders characterized by structural transition of the host-encoded cellular prion protein into the aberrantly folded pathologic isoform of the protein. Here is the latest research on diagnostic strategies for prion diseases.

December 31, 2021

Gelsolin Amyloidosis: aggregation propensities of wild and mutant peptides and their inhibition.

Alzheimer's & Dementia : the Journal of the Alzheimer's Association
Carlos Quintero Arias, Sanela Martic
December 29, 2021
Open Access

Validation and Application of Skin RT-QuIC to Patients in China with Probable CJD.

Pathogens
Kang XiaoXiaoping Dong
December 4, 2021

Seed amplification assays for diagnosing synucleinopathies: the issue of influencing factors.

Frontiers in Bioscience (Landmark Edition)
Giovanni BellomoLucilla Parnetti
November 22, 2021
Preprint
Open Access

A Field-Deployable Diagnostic Assay for the Visual Detection of Misfolded Prions

BioRxiv : the Preprint Server for Biology
P. R. ChristensonPeter A Larsen
September 1, 2021
Review
Open Access

Aptamer-based diagnostic and therapeutic approaches in animals: Current potential and challenges.

Saudi Journal of Biological Sciences
Sapna DeviMukesh Kumar Gupta
May 12, 2021
Review
Open Access

The importance of ongoing international surveillance for Creutzfeldt-Jakob disease.

Nature Reviews. Neurology
Neil WatsonSuvankar Pal
April 30, 2021
Review
Open Access

Development of molecular tools for diagnosis of Alzheimer's disease that are based on detection of amyloidogenic proteins.

Prion
Konstantin Y KulichikhinAleksandr A Rubel
April 9, 2021
Open Access

Detection of chronic wasting disease in mule and white-tailed deer by RT-QuIC analysis of outer ear.

Scientific Reports
Natalia C FerreiraByron Caughey
March 7, 2021
Open Access

Evaluation of plasma tau and neurofilament light chain biomarkers in a 12-year clinical cohort of human prion diseases.

Molecular Psychiatry
A. G. B. ThompsonSimon Mead
February 4, 2021
Review
Open Access

[Problems of ante mortem diagnostics of prion diseases].

Voprosy virusologii
S L Kal'novT V Grebennikova
January 30, 2021
Open Access

Tau-proximity ligation assay reveals extensive previously undetected pathology prior to neurofibrillary tangles in preclinical Alzheimer's disease.

Acta Neuropathologica Communications
Nora Bengoa-VergnioryJavier Alegre-Abarrategui
December 23, 2020
Review

Mini-Review: The MSA transcriptome.

Neuroscience Letters
Alexandra Pérez-Soriano, María J Martí
December 18, 2020
Open Access

Optimization of the Real-Time Quaking-Induced Conversion Assay for Prion Disease Diagnosis

Frontiers in Bioengineering and Biotechnology
Inga ZerrMatthias Schmitz
November 27, 2020
Open Access

Evaluation of Antemortem Diagnostic Techniques in Goats Naturally Infected With Scrapie

Frontiers in Veterinary Science
Najiba MammadovaJustin J Greenlee
November 14, 2020
Clinical Trial
Open Access

Ring trial of 2nd generation RT-QuIC diagnostic tests for sporadic CJD.

Annals of Clinical and Translational Neurology
Christina D OrruByron Caughey
August 29, 2020
Review
Open Access

Defining the Protein Seeds of Neurodegeneration using Real-Time Quaking-Induced Conversion Assays.

Biomolecules
Matteo Manca, Allison Kraus
August 28, 2020
Open Access

Second-Generation RT-QuIC Assay for the Diagnosis of Creutzfeldt-Jakob Disease Patients in Brazil

Frontiers in Bioengineering and Biotechnology
Breno José Alencar Pires BarbosaTuane C R G Vieira

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