Prion Disease

Prion diseases or transmissible spongiform encephalopathies are rare progressive neurogenerative diseases caused by misfolded prion proteins. Here is the latest research in this domain.

January 16, 2021

FUS and TDP-43 Phases in Health and Disease

Trends in Biochemical Sciences
Bede PortzJames Shorter
January 8, 2021

2,3,5,6-Tetramethylpyrazine protects retinal photoreceptors against endoplasmic reticulum stress by modulating ATF4-mediated inhibition of PRP aggregation

Journal of Molecular Medicine : Official Organ of the Gesellschaft Deutscher Naturforscher Und Ärzte
Hao HuangHuangxuan Shen
December 31, 2020
Open Access

Regional Differences in Neuroinflammation-Associated Gene Expression in the Brain of Sporadic Creutzfeldt-Jakob Disease Patients

International Journal of Molecular Sciences
Aušrinė AreškevičiūtėEva L Lund
January 15, 2021
Open Access

Structural and molecular basis of cross-seeding barriers in amyloids

Proceedings of the National Academy of Sciences of the United States of America
Asen DaskalovAntoine Loquet
December 23, 2020
Open Access

Exposure Risk of Chronic Wasting Disease in Humans

Satish K NemaniValerie L Sim
December 22, 2020

Familial Prion Disease: First Indian Kindred with Gerstmann-Sträussler-Scheinker Syndrome

Neurology India
Sameer BhatiaMandaville Gourie-Devi
December 29, 2020

Machine learning enables subtyping of sporadic CJD

Nature Reviews. Neurology
Ian Fyfe
December 22, 2020

Aβ Plaques

Free Neuropathology
Lary C Walker
January 4, 2021
Open Access

The engineered peptide construct NCAM1-Aβ inhibits aggregation of the human prion protein (PrP)

BioRxiv : the Preprint Server for Biology
M. GielnikSebastian K.T.S. Warmlander
January 6, 2021
Open Access

Complete microglia deficiency accelerates prion disease without enhancing CNS prion accumulation

BioRxiv : the Preprint Server for Biology
B. M. BradfordNeil A Mabbott
December 29, 2020
Case Report
Open Access

A Creutzfeldt-Jakob disease case misdiagnosed with acute cerebral infarction and review of the literature

Clinical Case Reports
Zhouwei Xu, Yuwu Zhao
December 18, 2020
Open Access

Amyotrophic Lateral Sclerosis: Proteins, Proteostasis, Prions, and Promises

Frontiers in Cellular Neuroscience
Luke McAlaryNeil R Cashman
January 12, 2021

Myoclonus-Ataxia Syndromes: A Diagnostic Approach

Movement Disorders Clinical Practice
Malco RossiBart van de Warrenburg
December 30, 2020
Open Access

Insoluble proteins catch heterologous soluble proteins into inclusion bodies by intermolecular interaction of aggregating peptides.

Jose Vicente CarrataláNeus Ferrer-Miralles
January 12, 2021
Open Access

Tau in Alzheimer's Disease: Pathological Alterations and an Attractive Therapeutic Target

Current Medical Science
Jian-Lan Gu, Fei Liu
January 9, 2021
Case Report
Open Access

Negative Diffusion Weighted Imaging on Magnetic Resonance Imaging of the Brain in Creutzfeldt-Jakob Disease

Case Reports in Neurological Medicine
Elijah LackeyAndy J Liu
January 14, 2021

How common are seizures in the heidenhain variant of creutzfeldt-jakob disease? A case report and systematic review

Journal of Clinical Neuroscience : Official Journal of the Neurosurgical Society of Australasia
Subramanian MuthusamyUdaya Seneviratne

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