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Prion Diseases: Biomarkers

Prion Diseases: Biomarkers diagram by

Prions are misfolded proteins which characterize several fatal neurodegenerative diseases. Prion proteins, as an important biomarker of prion disease, are responsible for the transmissible spongiform encephalopathies. Here is the latest research investigating biomarkers in prion diseases.

Top 20 most recent papers
Brain : a Journal of Neurology

CSF1R inhibitor JNJ-40346527 attenuates microglial proliferation and neurodegeneration in P301S mice

Brain : a Journal of NeurologySeptember 11, 2019
Renzo MancusoV Hugh Perry
64
1
1
40
bioRxiv

Genome-wide transcriptomics identifies an early preclinical signature of prion infection

bioRxivJanuary 11, 2020
Silvia SorceAdriano Aguzzi
11
bioRxiv

Characterization of the prion protein binding properties of antisense oligonucleotides

bioRxivNovember 7, 2019
Andrew G ReidenbachSonia M Vallabh
22
Pediatric Nephrology : Journal of the International Pediatric Nephrology Association

Aortic dilatation in children with mild to moderate chronic kidney disease

Pediatric Nephrology : Journal of the International Pediatric Nephrology AssociationJanuary 16, 2020
Peace C MaduemeMark Mitsnefes
bioRxiv

Human Tau Isoform Aggregation and Selective Detection of Misfolded Tau from Post-Mortem Alzheimer's Disease Brains

bioRxivJanuary 2, 2020
Ling WuBin Xu
6
NeuroImage. Clinical

Prion disease diagnosis using subject-specific imaging biomarkers within a multi-kernel Gaussian process

NeuroImage. ClinicalNovember 18, 2019
Liane S CanasMarc Modat
5
1
1
Ulusal travma ve acil cerrahi dergisi = Turkish journal of trauma & emergency surgery : TJTES

Evaluation of rat major celluler prion protein for early diagnosis in experimental rat brain trauma model

Ulusal travma ve acil cerrahi dergisi = Turkish journal of trauma & emergency surgery : TJTESJanuary 17, 2020
Alev KuralSezgin Sarıkaya
Journal of Neurology

Diagnostic value of surrogate CSF biomarkers for Creutzfeldt-Jakob disease in the era of RT-QuIC

Journal of NeurologySeptember 22, 2019
Samir Abu-RumeilehPiero Parchi
3
1
6
Expert Review of Molecular Diagnostics

Clinical implications of extracellular vesicles in neurodegenerative diseases

Expert Review of Molecular DiagnosticsAugust 21, 2019
Arada Vinaiphat, Siu Kwan Sze
2
1
4
PloS One

Neurofilaments in blood is a new promising preclinical biomarker for the screening of natural scrapie in sheep

PloS OneDecember 20, 2019
Henrik ZetterbergDaniela Meloni
1
1
European Journal of Vascular and Endovascular Surgery : the Official Journal of the European Society for Vascular Surgery

Reticulated Platelets as Predictor of Myocardial Injury and 30 Day Mortality After Non-cardiac Surgery

European Journal of Vascular and Endovascular Surgery : the Official Journal of the European Society for Vascular SurgeryDecember 10, 2019
Armelle J A MeershoekGert J de Borst
Journal of Neurology

Cerebrospinal fluid non-phosphorylated tau in the differential diagnosis of Creutzfeldt-Jakob disease: a comparative prospective study with 14-3-3

Journal of NeurologyNovember 9, 2019
Franc LlorensInga Zerr
2
1
1
Journal of Clinical Medicine

Growth Differentiation Factor-15 (GDF-15) is a Biomarker of Muscle Wasting and Renal Dysfunction in Preoperative Cardiovascular Surgery Patients

Journal of Clinical MedicineOctober 5, 2019
Toshiaki NakajimaTeruo Inoue
Frontiers in Neuroscience

Profiles of 14-3-3 and Total Tau in CSF Samples of Chinese Patients of Different Genetic Prion Diseases

Frontiers in NeuroscienceSeptember 26, 2019
Cao ChenXiao-Ping Dong
3
1
Frontiers in Cellular Neuroscience

Discrimination of Prion Strain Targeting in the Central Nervous System via Reactive Astrocyte Heterogeneity in CD44 Expression

Frontiers in Cellular NeuroscienceSeptember 26, 2019
Barry M BradfordNeil A Mabbott
16
1
2
European Journal of Internal Medicine

Serum 8-hydroxydeoxyguanosine, a marker of oxidative DNA damage, is associated with mortality independent of inflammation in chronic kidney disease

European Journal of Internal MedicineAugust 14, 2019
Lu DaiPeter Stenvinkel
Frontiers in Molecular Neuroscience

Role of Exosomes in Central Nervous System Diseases

Frontiers in Molecular NeuroscienceOctober 23, 2019
Wanying LiuJunping Zhang
9
1
17
Clinical Nutrition : Official Journal of the European Society of Parenteral and Enteral Nutrition

Serum creatinine to cystatin C ratio predicts skeletal muscle mass and strength in patients with non-dialysis chronic kidney disease

Clinical Nutrition : Official Journal of the European Society of Parenteral and Enteral NutritionNovember 17, 2019
Yu-Li LinBang-Gee Hsu
1
Stem Cells and Development

Autologous platelet lysate does not enhance chondrogenic differentiation of equine bone marrow-derived mesenchymal stromal cells despite increased TGF-β1 concentration

Stem Cells and DevelopmentDecember 6, 2019
Hannah-Sophie ChapmanKyla Ortved
Therapeutic Advances in Chronic Disease

Retinal correlates of neurological disorders

Therapeutic Advances in Chronic DiseaseDecember 14, 2019
Timothy E YapM Francesca Cordeiro
3
1

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