Prion Diseases: Biomarkers

Prions are misfolded proteins which characterize several fatal neurodegenerative diseases. Prion proteins, as an important biomarker of prion disease, are responsible for the transmissible spongiform encephalopathies. Here is the latest research investigating biomarkers in prion diseases.

September 16, 2020

Comparison between plasma and cerebrospinal fluid biomarkers for the early diagnosis and association with survival in prion disease

Journal of Neurology, Neurosurgery, and Psychiatry
Samir Abu-RumeilehPiero Parchi
December 2, 2020
Open Access

HAHmiR.DB: a server platform for high-altitude human miRNA-gene coregulatory networks and associated regulatory circuits

Database : the Journal of Biological Databases and Curation
Pankaj KhuranaBhuvnesh Kumar
September 15, 2020
Preprint
Open Access

Cognitive decline heralds onset of symptomatic inherited prion disease

MedRxiv : the Preprint Server for Health Sciences
J. MoleDiana Caine
August 11, 2020
Open Access

Prion protein lowering is a disease-modifying therapy across prion disease stages, strains and endpoints

Nucleic Acids Research
Eric Vallabh MinikelSonia M Vallabh
November 29, 2020

Effects of fibrinogen synthesis inhibition on vascular cognitive impairment during traumatic brain injury in mice

Brain Research
Nino MuradashviliDavid Lominadze
November 22, 2020

Immunological evaluation in vitro of nanoparticulate impurities isolated from pharmaceutical-grade sucrose

Journal of Pharmaceutical Sciences
Adam GrabarekWim Jiskoot
December 15, 2020
Review

Extracellular vesicles - propagators of neuropathology and sources of potential biomarkers and therapeutics for neurodegenerative diseases

Journal of Cell Science
Natasha VassileffAndrew F Hill
December 29, 2020
Open Access

Genetic sexing strains for the population suppression of the mosquito vector Aedes aegypti

Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences
Panagiota KoskiniotiKostas Bourtzis
August 24, 2020

The occurrence of prion protein in surgically resected pancreatic adenocarcinoma

Pancreatology : Official Journal of the International Association of Pancreatology (IAP) ... [et Al.]
Matteo BianchiniLuca Morelli
August 18, 2020
Review
Open Access

Extracellular vesicles and amyotrophic lateral sclerosis: from misfolded protein vehicles to promising clinical biomarkers

Cellular and Molecular Life Sciences : CMLS
Delia GagliardiStefania Corti
July 29, 2020
Preprint
Open Access

Evaluation of plasma tau and neurofilament light chain biomarkers in a 12-year clinical cohort of human prion diseases

MedRxiv : the Preprint Server for Health Sciences
Andrew ThompsonSimon Mead
June 19, 2020
Open Access

MicroRNA Alterations in a Tg501 Mouse Model of Prion Disease

Biomolecules
Janne M ToivonenInmaculada Martín-Burriel
November 13, 2020
Open Access

Fate and propagation of endogenously formed Tau aggregates in neuronal cells

EMBO Molecular Medicine
Patricia ChastagnerChiara Zurzolo
July 29, 2020
Review

Proteopathic Seed Amplification Assays for Neurodegenerative Disorders

Clinics in Laboratory Medicine
Natália do Carmo Ferreira, Byron Caughey
August 19, 2020
Review

Tau Pathology Triggered by Spinal Cord Injury Can Play a Critical Role in the Neurotrauma Development

Molecular Neurobiology
Elnaz NakhjiriKoorosh Shahpasand
August 2, 2020
Open Access

The Yarrowia lipolytica orthologs of Sup35p assemble into thioflavin T-negative amyloid fibrils

Biochemical and Biophysical Research Communications
Mehdi Kabani, Ronald Melki
January 10, 2021
Review
Open Access

The Role of Cellular Prion Protein in Promoting Stemness and Differentiation in Cancer

Cancers
Larisa RyskalinFrancesco Fornai
November 17, 2020
Review
Open Access

Challenges and Advances in Antemortem Diagnosis of Human Transmissible Spongiform Encephalopathies

Frontiers in Bioengineering and Biotechnology
Lucas M AscariYraima Cordeiro

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