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Prion Diseases: strain diversity and neurotoxicity

Prion Diseases: strain diversity and neurotoxicity diagram by ibreakstock, Shutterstock
ibreakstock, Shutterstock

Prions are misfolded proteins which characterize several fatal neurodegenerative diseases. Distinct prion strains are associated with different prion protein conformations and glycosylation patterns and associate with disease progression and severity. Here is the latest research on strain diversity and neurotoxicity in prion diseases.

Top 20 most recent papers
The Journal of Neuroscience : the Official Journal of the Society for Neuroscience

Extracellular Vesicles and Neurodegenerative Diseases

The Journal of Neuroscience : the Official Journal of the Society for NeuroscienceNovember 22, 2019
Andrew F Hill
21
1
1
Biological Reviews of the Cambridge Philosophical Society

The ecology of chronic wasting disease in wildlife

Biological Reviews of the Cambridge Philosophical SocietyNovember 22, 2019
Luis E EscobarClaudio Soto
23
13
Alzheimer's Research & Therapy

CSF biomarkers of neuroinflammation in distinct forms and subtypes of neurodegenerative dementia

Alzheimer's Research & TherapyJanuary 2, 2020
Samir Abu-RumeilehPiero Parchi
1
1
International Journal of Molecular Sciences

Exploring the Etiological Links behind Neurodegenerative Diseases: Inflammatory Cytokines and Bioactive Kynurenines

International Journal of Molecular SciencesApril 5, 2020
Masaru TanakaLászló Vécsei
Advances in Experimental Medicine and Biology

Structure of NFT: Biochemical Approach

Advances in Experimental Medicine and BiologyFebruary 26, 2020
Masato Hasegawa
1
Translational Neurodegeneration

Insights into the pathogenesis of multiple system atrophy: focus on glial cytoplasmic inclusions

Translational NeurodegenerationFebruary 26, 2020
Seiji KajiRyosuke Takahashi
3
1
The Journal of Biological Chemistry

A synthetic heparinoid blocks tau aggregate cell uptake and amplification

The Journal of Biological ChemistryJanuary 25, 2020
Barbara E StopschinskiMarc I Diamond
6
1
Tremor and Other Hyperkinetic Movements

Movement Disorders in Prionopathies: A Systematic Review

Tremor and Other Hyperkinetic MovementsDecember 25, 2019
Federico Rodriguez-PorcelAlberto J Espay
1
Molecular Therapy : the Journal of the American Society of Gene Therapy

The Amyloid Inhibitor CLR01 Relieves Autophagy and Ameliorates Neuropathology in a Severe Lysosomal Storage Disease

Molecular Therapy : the Journal of the American Society of Gene TherapyFebruary 23, 2020
Antonio MonacoAlessandro Fraldi
11
1
Current Opinion in Neurobiology

Preclinical biomarkers of prion infection and neurodegeneration

Current Opinion in NeurobiologyFebruary 29, 2020
Tze How Mok, Simon Mead
11
1
Frontiers in Molecular Neuroscience

Prionoid Proteins in the Pathogenesis of Neurodegenerative Diseases

Frontiers in Molecular NeuroscienceNovember 30, 2019
Cameron WellsNitin K Saksena
3
1
42
1

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