Prion Neurodegeneration

Prion diseases are fatal, transmissible, neurodegenerative diseases caused by the misfolding of the prion protein (prp). Here is the latest research on prion diseases.

July 17, 2020

Autophagy and Alzheimer's Disease

Advances in Experimental Medicine and Biology
Sheng ChenWeidong Le
July 24, 2020
Review
Open Access

POSCAbilities: The Application of the Prion Organotypic Slice Culture Assay to Neurodegenerative Disease Research

Biomolecules
Hailey Pineau, Valerie Sim
July 23, 2020
Open Access

α-synuclein strains that cause distinct pathologies differentially inhibit proteasome

ELife
Genjiro SuzukiMasato Hasegawa
August 2, 2020

Identification of the prion-related protein gene (PRNT) sequences in various species of the Cervidae family

Molecular Biology Reports
In-Soon RohByung-Hoon Jeong
August 11, 2020
Open Access

Prion protein lowering is a disease-modifying therapy across prion disease stages, strains and endpoints

Nucleic Acids Research
Eric Vallabh MinikelSonia M Vallabh
August 6, 2020
Open Access

Differential protein expression in diverse brain areas of Parkinson's and Alzheimer's disease patients

Scientific Reports
A R Esteves, S M Cardoso
August 3, 2020

Intracisternal injection of beta-amyloid seeds promotes cerebral amyloid angiopathy

Brain, Behavior, and Immunity
Qiuju YuanZhi-Xiu Lin
August 5, 2020

Benzimidazole based fluorophores for the detection of amyloid fibrils with higher sensitivity than Thioflavin-T

Journal of Neurochemistry
Narayanaperumal PravinMaheswaran Shanmugam
August 10, 2020

A blood miRNA signature associates with sporadic Creutzfeldt-Jakob disease diagnosis

Nature Communications
Penny J NorsworthyEmmanuelle A Viré
August 11, 2020
Case Report
Open Access

Dressing Apraxia as Initial Manifestation of Creutzfeldt-Jakob Disease

Tremor and Other Hyperkinetic Movements
Josef G HeckmannStefan Schwab
July 29, 2020
Preprint
Open Access

Evaluation of plasma tau and neurofilament light chain biomarkers in a 12-year clinical cohort of human prion diseases

MedRxiv : the Preprint Server for Health Sciences
A. ThompsonSimon H Mead
July 17, 2020

Autophagy and Parkinson's Disease

Advances in Experimental Medicine and Biology
Jiahong LuZhenyu Yue
August 2, 2020

Conformation-dependent membrane permeabilization by neurotoxic PrP oligomers: The role of the H2H3 oligomerization domain

Archives of Biochemistry and Biophysics
Cécile HuinSylvie Noinville
July 31, 2020

α-Synuclein in Parkinson's Disease: Does a Prion-Like Mechanism of Propagation from Periphery to the Brain Play a Role?

The Neuroscientist : a Review Journal Bringing Neurobiology, Neurology and Psychiatry
Huimin ZhengYuming Xu
July 18, 2020
Open Access

FRET-based Tau seeding assay does not represent prion-like templated assembly of Tau filaments

Molecular Neurodegeneration
Senthilvelrajan KaniyappanEckhard Mandelkow

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