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Protein Function Prediction

Protein Function Prediction  diagram by David Eccles
David Eccles

Protein function prediction methods are techniques that bioinformatics researchers use to assign biological or biochemical roles to proteins. Discover the latest research on protein function prediction here.

Top 20 most recent papers
Cold Spring Harbor Perspectives in Biology

Approaches for Understanding the Mechanisms of Long Noncoding RNA Regulation of Gene Expression

Cold Spring Harbor Perspectives in BiologyDecember 2, 2019
Patrick E McDonel, Mitchell Guttman
3
Cell Structure and Function

N-glycosylation of Rim21 at an unconventional site fine-tunes its behavior in the plasma membrane

Cell Structure and FunctionNovember 30, 2019
Keisuke ObaraTakumi Kamura
Nature Cell Biology

TBKBP1 and TBK1 form a growth factor signalling axis mediating immunosuppression and tumourigenesis

Nature Cell BiologyDecember 2, 2019
Le-Le ZhuShao-Cong Sun
6
3
EBioMedicine

Human iPSC-derived astrocytes from ALS patients with mutated C9ORF72 show increased oxidative stress and neurotoxicity

EBioMedicineNovember 28, 2019
Anastasya BirgerBenjamin E Reubinoff
1
EMBO Molecular Medicine

Blockade of IGF2R improves muscle regeneration and ameliorates Duchenne muscular dystrophy

EMBO Molecular MedicineDecember 2, 2019
Pamela BellaYVAN TORRENTE
ACS Nano

Discovery of Stable and Selective Antibody Mimetics from Combinatorial Libraries of Polyvalent, Loop-Functionalized Peptoid Nanosheets

ACS NanoDecember 2, 2019
Jae Hong KimRonald N. Zuckermann
bioRxiv

Quantifying the heterogeneity of macromolecular machines by mass photometry

bioRxivDecember 4, 2019
Adar Sonn SegevPhilipp Kukura
15
bioRxiv

Highly clustered de novo frameshift variants in the neuronal splicing factor NOVA2 result in a specific abnormal C terminal part and cause a severe form of intellectual disability with autistic features.

bioRxivDecember 4, 2019
Francesca MattioliAmelie M Piton
The Journal of Biological Chemistry

Comparative structure-function analysis of bromodomain and extraterminal motif (BET) proteins in a gene-complementation system

The Journal of Biological ChemistryDecember 2, 2019
Michael T WernerGerd A. Blobel
Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences

Impact of mitonuclear interactions on life-history responses to diet

Philosophical Transactions of the Royal Society of London. Series B, Biological SciencesDecember 4, 2019
M. Florencia CamusNick Lane
20
Alzheimer's Research & Therapy

Characterization of the selective in vitro and in vivo binding properties of crenezumab to oligomeric Aβ

Alzheimer's Research & TherapyDecember 1, 2019
William J MeilandtJasvinder K Atwal
Maturitas

Analysis of NR5A1 in 142 patients with premature ovarian insufficiency, diminished ovarian reserve, or unexplained infertility

MaturitasDecember 4, 2019
Sylvie JaillardAndrew James Sinclair
bioRxiv

A complex IRES at the 5'-UTR of a viral mRNA assembles a functional 48S complex via an uAUG intermediate.

bioRxivDecember 4, 2019
Ritam NeupaneIsrael S. Fernandez
5
Kidney International

The deacetylase sirtuin 6 protects against kidney fibrosis by epigenetically blocking β-catenin target gene expression

Kidney InternationalSeptember 17, 2019
Juan CaiZheng Dong
Intensive Care Medicine Experimental

Combination of cardiac and thoracic pump theories in rodent cardiopulmonary resuscitation: a new method of three-side chest compression

Intensive Care Medicine ExperimentalDecember 2, 2019
Yu OkumaLance B Becker
Hypertension

Classical Dendritic Cells Mediate Hypertension by Promoting Renal Oxidative Stress and Fluid Retention

HypertensionDecember 2, 2019
Xiaohan LuSteven D Crowley
2
bioRxiv

LIPID ANCHORING OF ARCHAEOSORTASE SUBSTRATES AND MID-CELL GROWTH IN HALOARCHAEA

bioRxivDecember 4, 2019
Mohd Farid Abdul-HalimMechthild Pohlschröder
3
bioRxiv

Interrogating mechanisms of ssDNA binding to a viral HUH-endonuclease by alanine scanning of an electrostatic patch

bioRxivDecember 4, 2019
Andrew J NelsonWendy Ryan Gordon
4
bioRxiv

End-to-end multitask learning, from protein language to protein features without alignments

bioRxivDecember 4, 2019
Ahmed ElnaggarBurkhard Rost
7
Hypertension

Adenosine 2A Receptor Activation Contributes to Ang II-Induced Aortic Remodeling by Promoting Macrophage Retention

HypertensionDecember 2, 2019
Zuowen HeDao Wen Wang

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