Protein Kinases & Mitosis

Phosphorylation-dependent changes orchestrate almost every step of cell division, from entry into mitosis to cytokinesis. These changes are mediated by several different protein kinases, including the Aurora and Cyclin-dependent kinases. Here is the latest research examining the role of protein kinases in mitosis.

January 12, 2022
Open Access

The Role of LIM Kinase in the Male Urogenital System.

Juhyun ParkMin Chul Cho
January 11, 2022
Open Access

Cyclin-Dependent Kinase Inhibitors and Their Therapeutic Potential in Colorectal Cancer Treatment.

Frontiers in Pharmacology
Oana-Maria ThomaMaximilian J Waldner
January 2, 2022
Open Access

Cooperative regulation of C1-domain membrane recruitment polarizes atypical Protein Kinase C

BioRxiv : the Preprint Server for Biology
K. A. JonesKen Prehoda
January 1, 2022

Identifying Cyclin A/Cdk1 Substrates in Mitosis in Human Cells.

Methods in Molecular Biology
Ana Maria G Dumitru, Duane A Compton
December 30, 2021
Open Access

VRK1 is required in VRK2-methylated cancers of the nervous system

BioRxiv : the Preprint Server for Biology
J. SoWilliam C. Hahn
December 27, 2021

FDI-6 and olaparib synergistically inhibit the growth of pancreatic cancer by repressing BUB1, BRCA1 and CDC25A signaling pathways.

Pharmacological Research : the Official Journal of the Italian Pharmacological Society
Shi-Qi WuShu-Ping Wang
December 22, 2021

Protein Phosphatase 2A-Dependent Mitotic hnRNPA1 Dephosphorylation and TERRA Formation Facilitate Telomere Capping.

Molecular Cancer Research : MCR
Jiang-Dong SuiYong-Zhong Wu
December 19, 2021

Interaction of DBC1 with polyoma small T antigen promotes its degradation and negatively regulates tumorigenesis.

The Journal of Biological Chemistry
Zarka SarwarShaida Andrabi
December 17, 2021

LRRK2 regulates actin assembly for spindle migration and mitochondrial function in mouse oocyte meiosis.

Journal of Molecular Cell Biology
Zhen-Nan PanShao-Chen Sun
December 16, 2021
Open Access

Mitotic spindle formation in the absence of Polo kinase

BioRxiv : the Preprint Server for Biology
J. Kim, Gohta Goshima
December 16, 2021

More than Two Populations of Microtubules Comprise the Dynamic Mitotic Spindle.

Journal of Cell Science
Aaron R Tipton, Gary J Gorbsky
December 16, 2021

Interaction of obtusilactone B and related butanolide lactones with the barrier-to-autointegration factor 1 (BAF1). A computational study.

Current Research in Pharmacology and Drug Discovery
Christian Bailly, Gérard Vergoten
December 16, 2021

Overexpression of NEK2 is correlated with poor prognosis in human clear cell renal cell carcinoma.

International Journal of Immunopathology and Pharmacology
Chenfeng WangXu Zhang

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