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Protein Localization in Disease & Therapy

Protein Localization in Disease & Therapy diagram by Masaki et al, PLOS Pathogens
Masaki et al, PLOS Pathogens

Localization of proteins is critical for ensuring the correct location for physiological functioning. If an error occurs, diseases such as cardiovascular, neurodegenerative disorders and cancers can present. Therapies are being explored to target this mislocalization. Here is the latest research on protein localization in disease and therapy.

Top 20 most recent papers
International Journal of Molecular Sciences

Long Noncoding RNA and Epithelial Mesenchymal Transition in Cancer

International Journal of Molecular SciencesApril 21, 2019
Mila Gugnoni, Alessia Ciarrocchi
International Physiology Journal

Substrate Stiffness Influences the Time Dependence of CTGF Protein Expression in Müller Cells

International Physiology JournalAugust 21, 2018
Joshua T Davis, William J Foster
ILAR Journal

Beyond the H&E: Advanced Technologies for in situ Tissue Biomarker Imaging

ILAR JournalNovember 22, 2018
Lauren E HimmelKelli L Boyd
Nature Structural & Molecular Biology

Structural basis of the filamin A actin-binding domain interaction with F-actin

Nature Structural & Molecular BiologySeptember 19, 2018
Daniel V IwamotoDavid A Calderwood
Human Molecular Genetics

Nuclear localization and phosphorylation modulate pathological effects of alpha-synuclein

Human Molecular GeneticsSeptember 17, 2018
Raquel PinhoTiago F Outeiro
Saudi Pharmaceutical Journal : SPJ : the Official Publication of the Saudi Pharmaceutical Society

Prediction of Chlamydia pneumoniae protein localization in host mitochondria and cytoplasm and possible involvements in lung cancer etiology: a computational approach

Saudi Pharmaceutical Journal : SPJ : the Official Publication of the Saudi Pharmaceutical SocietySeptember 1, 2018
Aws AlshamsanKhalid Alsaleh
Journal of Cellular Physiology

Functions and regulatory mechanisms of metastasis-associated lung adenocarcinoma transcript 1

Journal of Cellular PhysiologyAugust 23, 2018
Li LeiQinghai Zeng
Cancer Biology & Therapy

ELF3 is an antagonist of oncogenic-signalling-induced expression of EMT-TF ZEB1

Cancer Biology & TherapyAugust 28, 2018
D LiuR M Ewing
PLoS Computational Biology

Proteome-scale relationships between local amino acid composition and protein fates and functions

PLoS Computational BiologySeptember 25, 2018
Sean M Cascarina, Eric D Ross
Molecular & Cellular Proteomics : MCP

Stress-induced Changes in the S-palmitoylation and S-nitrosylation of Synaptic Proteins

Molecular & Cellular Proteomics : MCPJuly 18, 2019
Monika Zareba-KoziolJakub Wlodarczyk
Frontiers in Microbiology

Methods for Lipid Droplet Biophysical Characterization in Flaviviridae Infections

Frontiers in MicrobiologySeptember 7, 2018
Ana S MartinsNuno C Santos

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