Protein Localization in Disease & Therapy

Localization of proteins is critical for ensuring the correct location for physiological functioning. If an error occurs, diseases such as cardiovascular, neurodegenerative disorders and cancers can present. Therapies are being explored to target this mislocalization. Here is the latest research on protein localization in disease and therapy.

September 11, 2019

In vivo functionalization of diatom biosilica with sodium alendronate as osteoactive material

Materials Science & Engineering. C, Materials for Biological Applications
Stefania R CiccoGianluca M Farinola
May 28, 2019
Open Access

Dysfunction of Cellular Proteostasis in Parkinson's Disease

Frontiers in Neuroscience
Šárka LehtonenJari Koistinaho
October 20, 2018

Heat Shock Proteins as a Potential Therapeutic Target in the Treatment of Gestational Diabetes Mellitus: What We Know so Far

International Journal of Molecular Sciences
Katarzyna E Skórzyńska-DziduszkoBożena Leszczyńska-Gorzelak
September 14, 2019

Interleukin-6 selectively induces drug metabolism to potentiate the genotoxicity of dietary carcinogens in mammary cells

Archives of Toxicology
Durr-E-Shahwar MalikNigel J Gooderham
February 14, 2019
Open Access

Genome-wide association study identifies 44 independent genomic loci for self-reported adult hearing difficulty in the UK Biobank cohort

BioRxiv : the Preprint Server for Biology
Helena R R WellsFrances MK Wiliams
June 9, 2020

An in silico map of the SARS-CoV-2 RNA Structurome

BioRxiv : the Preprint Server for Biology
Ryan J AndrewsWalter N Moss
November 20, 2019
Open Access

Proteostasis In The Endoplasmic Reticulum: Road to Cure

Su Min Nam, Young Joo Jeon
September 14, 2019
Open Access

Proteostasis and Energetics as Proteome Hallmarks of Aging and Influenza Challenge in Pulmonary Disease

BioRxiv : the Preprint Server for Biology
Salvatore LoguercioWilliam E Balch
June 5, 2020
Open Access

Biophysical studies of protein misfolding and aggregation in in vivo models of Alzheimer's and Parkinson's diseases

Quarterly Reviews of Biophysics
Tessa SinnigeMichele Vendruscolo
April 13, 2019

Role of endoplasmic reticulum stress and protein misfolding in disorders of the liver and pancreas

Advances in Medical Sciences
Jan LukasMatthias Sendler
February 20, 2020

The impact of proteostasis dysfunction secondary to environmental and genetic causes on neurodegenerative diseases progression and potential therapeutic intervention

Environmental Science and Pollution Research International
Abdelmagid M ElmatbolyMohamed M Abdel-Daim
May 8, 2019
Open Access

RhoA regulates translation of the Nogo-A decoy SPARC in white matter-invading glioblastomas

Acta Neuropathologica
Peter WirthschaftBjörn Tews
July 20, 2019
Open Access

Prion disease is accelerated in mice lacking stress-induced heat shock protein 70 (HSP70)

The Journal of Biological Chemistry
Charles E MaysClaudio Soto

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