Proteolysis

Proteolysis refers to the breakdown of proteins into amino acids or shorter polypeptides. Discover the latest research on mechanism that underlie proteolysis here.

January 17, 2022

Branched ubiquitin code: from basic biology to targeted protein degradation.

Journal of Biochemistry
Fumiaki Ohtake
January 17, 2022
Review
Open Access

Antioxidant Effects of Irisin in Liver Diseases: Mechanistic Insights.

Oxidative Medicine and Cellular Longevity
Junzhou ZhaoRongqian Wu
January 17, 2022

Chronic Alcohol Exposure Alters Gene Expression and Neurodegeneration Pathways in the Brain of Adult Mice.

Journal of Alzheimer's Disease : JAD
Mingjing LiuWeihong Song
January 15, 2022
Preprint
Open Access

Structure-Based Survey of the Human Proteome for Opportunities in Proximity Pharmacology

BioRxiv : the Preprint Server for Biology
E. Rovers, Matthieu Schapira
January 15, 2022
Open Access

Pterostilbene downregulates BCR/ABL and induces apoptosis of T315I-mutated BCR/ABL-positive leukemic cells.

Scientific Reports
Shohei KawakamiHiroshi Kawada
January 15, 2022

Primary skeletal muscle cells from chronic kidney disease patients retain hallmarks of cachexia in vitro.

Journal of Cachexia, Sarcopenia and Muscle
Luke A BakerEmma L Watson
January 14, 2022
Preprint
Open Access

Time-lapsed proteomics reveals a role for the novel protein, SNED1, in modulating ECM composition and protein folding

BioRxiv : the Preprint Server for Biology
F. LeeAlexandra Naba
January 15, 2022

Cholangiocarcinoma progression depends on the uptake and metabolization of extracellular lipids.

Hepatology : Official Journal of the American Association for the Study of Liver Diseases
Mikel Ruiz de GaunaPatricia Aspichueta
January 15, 2022

Drug library screen identifies inhibitors of toxic astrogliosis.

Multiple Sclerosis and Related Disorders
Ruturaj MasvekarBibiana Bielekova
January 14, 2022

Determination of the metabolic pathways for degradation of naphthalene and pyrene in Amycolatopsis sp. Poz14.

Comparative Biochemistry and Physiology. Toxicology & Pharmacology : CBP
Humberto PeraltaJanet Jan-Roblero
January 14, 2022

Codonopsis lanceolata ameliorates sarcopenic obesity via recovering PI3K/Akt pathway and lipid metabolism in skeletal muscle.

Phytomedicine : International Journal of Phytotherapy and Phytopharmacology
Min Ji Han, Se-Young Choung
January 13, 2022
Preprint
Open Access

Rapid and specific degradation of endogenous proteins in mouse models using auxin-inducible degrons

BioRxiv : the Preprint Server for Biology
L. A. MacdonaldAndrew J Wood
January 13, 2022
Preprint
Open Access

Proteasome granular localization is regulated through mitochondrial respiration and kinase signaling

BioRxiv : the Preprint Server for Biology
K. A. Waite, Jeroen Roelofs
January 14, 2022
Review

F-box only protein 9 and its role in cancer.

Molecular Biology Reports
Shujaat HussainHongmin Liu
January 14, 2022

Detection and quantification of the vacuolar H+ATPase using the Legionella effector protein SidK.

The Journal of Cell Biology
Michelle E MaxsonJohn L Rubinstein
January 14, 2022

Photo-activated proflavine degrades protein and impairs enzyme activity: Involvement of hydroxyl radicals.

Toxicology Reports
Mansour K GhatashehAbdullah S Alhomida

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