Proteolysis refers to the breakdown of proteins into amino acids or shorter polypeptides. Discover the latest research on mechanism that underlie proteolysis here.
α-Synuclein is an integral component of Lewy bodies which are comprised of protein clumps and are a pathological hallmark of Parkinson’s disease. Here is the latest research on α-synuclein structure and function.
Bacterial protein structures can expedite the development of novel antibiotics. Here is the latest research on bacterial proteins and the resolution of their structures.
Bioenergetic processes, including cellular respiration and photosynthesis, concern the transformation of energy by cells. Here is the latest research on the role of calcium in bioenergetics.
Key regulators of cell cycle, including cyclins, cyclin dependent kinase inhibitors, DNA replication factors, are controlled by proteolysis. Discover the latest research on cell cycle control and proteolysis.
Chaperones are proteins that play an essential role in protein folding, stability, assembly, and degradation. Their depletion or dysfunction has been implicated in protein folding disorders. Here is the latest research.
Chemoproteomics is an approach to discovering mechanisms for regulating biological pathways for the purpose of designing new pharmaceutical therapies. Here is the latest research on this chemical proteomic method for pharmacological discovery research.
Cholesterol is essential for a variety of cellular processes, including cell growth and division, and it plays an important role in various signaling pathways. Here is the latest research on cholesterol synthesis and the role of cholesterol in cell signaling.
Cryogenic electron microscopy (Cryo-EM) allows the determination of biological macromolecules and their assemblies at a near-atomic resolution. Here is the latest research.
Investigating human cellular proteins through a combination of highly multiplexed imaging and proteomic analyses can help characterize all human cells at the proteomic level. Discover the latest research on deep visual proteomics here.
This feed focuses on endoplasmic reticulum biochemistry, and includes ER stress and the unfolded protein response.