PSCs in Development and Disease

Pluripotent stem cells (PSCs) are progenitor cells that can give rise to three basic layers of the body, thus potentially allowing the production of any cells or tissues needed by the body for repair. Here is the latest research on the PSCs in development and disease.

January 21, 2022
Preprint
Open Access

Longitudinal Morphological and Functional Characterization of Human Heart Organoids Using Optical Coherence Tomography

BioRxiv : the Preprint Server for Biology
Y. MingChao Zhou
January 21, 2022

Dimethyl Fumarate Reduces Inflammation in Chronic Active Multiple Sclerosis Lesions.

Neurology. Neuroimmunology and Neuroinflammation
Nicole ZingerSusan A Gauthier
January 21, 2022

SUPT4H1-edited stem cell therapy rescues neuronal dysfunction in a mouse model for Huntington's disease.

Npj Regenerative Medicine
Hyun Jung ParkJihwan Song
January 21, 2022
Review
Open Access

An Integrated Approach to Studying Rare Neuromuscular Diseases Using Animal and Human Cell-Based Models.

Frontiers in Cell and Developmental Biology
Timothy J HinesRobert W Burgess
January 21, 2022
Open Access

A Bioprinted Heart-on-a-Chip with Human Pluripotent Stem Cell-Derived Cardiomyocytes for Drug Evaluation.

Bioengineering
Alan Faulkner-JonesWenmiao Shu
January 21, 2022

Passive immunization against phosphorylated tau improves features of Huntington's disease pathology.

Molecular Therapy : the Journal of the American Society of Gene Therapy
Melanie AlpaughFrancesca Cicchetti
January 21, 2022
Preprint
Open Access

Multi-omic rejuvenation of naturally aged tissues by a single cycle of transient reprogramming

BioRxiv : the Preprint Server for Biology
D. ChondronasiouManuel Serrano
January 20, 2022
Preprint
Open Access

BIN1 regulates electrical activity and network synchronization in hiPSC-derived neurons

BioRxiv : the Preprint Server for Biology
O. SahaMarcos Romualdo Costa
January 20, 2022
Preprint
Open Access

Xeno-free induced pluripotent stem cell-derived neural progenitor cells for in vivo applications

BioRxiv : the Preprint Server for Biology
R. RustChristian Tackenberg
January 20, 2022
Preprint
Open Access

High-Throughput Screening for Myelination Promoting Compounds Using Human Stem Cell-derived Oligodendrocyte Progenitor Cells Identifies Novel Targets

BioRxiv : the Preprint Server for Biology
Xitiz Cham LiXitiz Chamling
January 20, 2022
Open Access

Automated evaluation of retinal pigment epithelium disease area in eyes with age-related macular degeneration.

Scientific Reports
Naohiro MotozawaMichiko Mandai
January 20, 2022

Bioengineered models of Parkinson's disease using patient-derived dopaminergic neurons exhibit distinct biological profiles in a 3D microenvironment.

Cellular and Molecular Life Sciences : CMLS
Nicholas J FioreDavid L Kaplan
January 20, 2022

Nanoarchitectonics of a Microsphere-Based Scaffold for Modeling Neurodevelopment and Neurological Disease.

ACS Applied Bio Materials
Eric S SandhurstKevin R Francis

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