REDOX Signaling in Aging

The redox theory of aging is that aging is a decline in plasticity of genome-exposome interaction that occurs as a consequence of execution of differentiation and exposure memory systems. This includes compromised mitochondrial and bioenergetic flexibility, impaired food utilization and metabolic homeostasis, decreased barrier and defense capabilities and loss of reproductive fidelity and fecundity. This theory accounts for hallmarks of aging, including failure to maintain oxidative or xenobiotic defenses, mitochondrial integrity, proteostasis, barrier structures, DNA repair, telomeres, immune function, metabolic regulation and regenerative capacity.

August 1, 2020
Review
Open Access

Integrating Ultra-Weak Photon Emission Analysis in Mitochondrial Research

Frontiers in Physiology
Roeland Van WijkJinxiang Han
July 29, 2020
Open Access

Biochemical Profile of the Soybean Seed Embryonic Axis and Its Changes during Accelerated Aging

Biology
Luciano Antônio EboneGeraldo Chavarria
August 5, 2020

Noble metal alloy nanoparticles coated flexible MoS2 paper for the determination of reactive oxygen species

Biosensors & Bioelectronics
Yao YaoJianfeng Ping
August 5, 2020
Review

Specialized pro-resolving mediators: It's anti-oxidant stress role in multiple disease models

Molecular Immunology
Fuquan WangShanglong Yao
August 6, 2020
Review
Open Access

Implication of Hyperhomocysteinemia in Blood Retinal Barrier (BRB) Dysfunction

Biomolecules
Amany TawfikMohamed Al-Shabrawey
August 3, 2020

APOE and metabolic dysfunction in Alzheimer's disease

International Review of Neurobiology
Lance A Johnson
August 4, 2020

Effects of resistance training on mitochondrial function in skeletal muscle of aging rats

Zhongguo ying yong sheng li xue za zhi = Zhongguo yingyong shenglixue zazhi = Chinese journal of applied physiology
Yan-Hong SuShi-Chao Zhang
July 29, 2020
Open Access

The SEM-4 Transcription Factor Is Required for Regulation of the Oxidative Stress Response in Caenorhabditis elegans

G3 : Genes - Genomes - Genetics
Adilya RafikovaTerrance J Kubiseski
July 30, 2020

Hemiterpene compound, 3,3-dimethylallyl alcohol promotes longevity and neuroprotection in Caenorhabditis elegans

GeroScience
Suresh Chandra PhularaVirendra Shukla
August 1, 2020
Review
Open Access

Effect of Nitrogen Reactive Compounds on Aging in Seed

Frontiers in Plant Science
Katarzyna CiackaAgnieszka Gniazdowska
July 31, 2020
Open Access

DCAF1 regulates Treg senescence via the ROS axis during immunological ageing

The Journal of Clinical Investigation
Zengli GuoYisong Y Wan
July 29, 2020
Review
Open Access

Endothelial Dysfunction in Chronic Kidney Disease, from Biology to Clinical Outcomes: A 2020 Update

Journal of Clinical Medicine
Stefanos RoumeliotisCarmine Zoccali
July 29, 2020

Trimethylamine-N-Oxide: Heart of the microbiota-cardiovascular disease nexus?

Nutrition Research Reviews
Saba NaghipourJohn P Headrick

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