Riboswitches and Ribozymes

Ribozymes are catalytic RNAs that interact with a variety of small molecule substrates and cofactors, the intracellular abundance of which are sensed by riboswitches that modulate transcription, RNA stability, or translation. Here is the latest research.

September 17, 2021

Controlling gene expression in mammalian cells using multiplexed conditional guide RNAs for Cas12a.

Angewandte Chemie
Oesinghaus Lukas, Friedrich Christian Simmel
September 15, 2021
Open Access

Non-enzymatic assembly of active chimeric ribozymes from aminoacylated RNA oligonucleotides

BioRxiv : the Preprint Server for Biology
A. RadakovicJack W Szostak
September 16, 2021

DIMPL: a bioinformatics pipeline for the discovery of structured noncoding RNA motifs in bacteria.

Kenneth I BrewerRonald R Breaker
September 15, 2021

The substitution spectra of coronavirus genomes.

Briefings in Bioinformatics
Diego ForniManuela Sironi
September 14, 2021

Targeting riboswitches with synthetic small RNAs for metabolic engineering.

Metabolic Engineering
Milca Rachel da Costa Ribeiro LinsDanielle Biscaro Pedrolli
September 14, 2021

The many faces of RNA-based RNase P, an RNA-world relic.

Trends in Biochemical Sciences
Hong-Duc PhanVenkat Gopalan
September 13, 2021

Role of long non-coding RNAs in Down syndrome patients: a transcriptome analysis study.

Human Cell
Michele SalemiCorrado Romano
September 9, 2021

adabmDCA: Adaptive Boltzmann machine learning for biological sequences

Anna Paola MuntoniFrancesco Zamponi
September 11, 2021
Open Access

iPLA2-VIA is required for healthy aging of neurons, muscle, and the female germline in Drosophila melanogaster.

PloS One
Surya Jyoti BanerjeeJosefa Steinhauer
September 10, 2021
Open Access

Cytosolic aspartate aminotransferase moonlights as a ribosome binding modulator of Gcn2 activity during oxidative stress

BioRxiv : the Preprint Server for Biology
R. A. CrawfordGraham D Pavitt
September 10, 2021

The RaPID Platform for the Discovery of Pseudo-Natural Macrocyclic Peptides.

Accounts of Chemical Research
Yuki Goto, Hiroaki Suga
September 10, 2021

Integrative analysis of miRNA-mRNA expression profiles in esophageal fibrosis after ESD.

Experimental and Therapeutic Medicine
Yin Zhang, Chunfang Xu
September 10, 2021

Author Correction: Heat flows in rock cracks naturally optimize salt compositions for ribozymes.

Nature Chemistry
T MatreuxC B Mast
September 9, 2021
Open Access

Witnessing the structural evolution of an RNA enzyme.

Xavier PortilloGerald F Joyce
September 8, 2021

How to Kinetically Dissect an RNA Machine.

Rhiju Das, Rick Russell
September 9, 2021

5'-Cap sequestration is an essential determinant of HIV-1 genome packaging.

Proceedings of the National Academy of Sciences of the United States of America
Pengfei DingMichael F Summers
September 9, 2021

Beyond the Plateau: pL Dependence of Proton Inventories as a Tool for Studying Ribozyme and Ribonuclease Catalysis.

Suhyun Yoon, Michael E Harris
September 7, 2021

Structural basis of RNA processing by human mitochondrial RNase P.

Nature Structural & Molecular Biology
Arjun BhattaHauke S Hillen

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