Ribozymes are catalytic RNAs that interact with a variety of small molecule substrates and cofactors, the intracellular abundance of which are sensed by riboswitches that modulate transcription, RNA stability, or translation. Here is the latest research.
ATP synthases are enzymes located in the inner mitochondrial membrane that catalyze the synthesis of ATP during cellular respiration. Discover the latest research on ATP synthases here.
This feed focuses on biomimetrics, synthetic biology and bio- and tissue-engineering approaches used for modeling human diseases.
This feed focuses on broad characteristics of the CRISPR system and the proteins associated with it.
Biosyntheic transformtions are multi-step, enzyme-catalyzed processes where substrates are converted into more complex products in living organisms. Simple compounds are modified, converted into other compounds, or joined together to form macromolecules. Discover the latest research on biosynthetic transformations here.
Chaperones are proteins that play an essential role in protein folding, stability, assembly, and degradation. Their depletion or dysfunction has been implicated in protein folding disorders. Here is the latest research.
Chromatin remodeling is essential for regulation of gene expression, DNA replication, as well as DNA repair. Here is the latest research on chromatin remodeling complexes and mechanisms underlying chromatin remodeling.
This feed focuses on structure and function of coenzymes in catalytic reactions, including cellular redox systems.
This feed focuses on cytochromes, including cytochrome C and the cytochromes P450 (CYP) enzyme system, and their involvement in the activation and inactivation of drugs.
Cells are subjected to several DNA damaging events on a daily basis which results in the induction of DNA damage signaling and repair cascades to ensure genomic stability. Here is the latest research pertaining to DNA damage.
Development of gene editing techniques, including CRISPR and TALENs, has relied on mechanisms that underlie DNA repair and genome stability pathways. This feed focuses on the role of DNA repair mechanisms in gene editing and genetic engineering.