Riboswitches and Ribozymes

Ribozymes are catalytic RNAs that interact with a variety of small molecule substrates and cofactors, the intracellular abundance of which are sensed by riboswitches that modulate transcription, RNA stability, or translation. Here is the latest research.

May 6, 2020
ReviewOpen Access

Developments of Riboswitches and Toehold Switches for Molecular Detection-Biosensing and Molecular Diagnostics

International Journal of Molecular Sciences
Tin Hoang Trung ChauEun Yeol Lee
April 5, 2020
Open Access

Single Mutation in Hammerhead Ribozyme Favors Cleavage Activity with Manganese over Magnesium

Non-coding RNA
Mohammad Reza NaghdiJonathan Perreault
May 1, 2020
Open Access

Tunable self-cleaving ribozymes for modulating gene expression in eukaryotic systems

PloS One
Thomas JacobsenGregory T Reeves
May 31, 2020

A decade of research on the second messenger c-di-AMP

FEMS Microbiology Reviews
Wen YinJin He
May 27, 2020

Deciphering the Self-Cleavage Reaction Mechanism of Hairpin Ribozyme

The Journal of Physical Chemistry. B
Narendra Kumar, Dominik Marx
May 21, 2020

A Gram-Negative Antibiotic Active Through Inhibition of an Essential Riboswitch

Journal of the American Chemical Society
Stephen E MotikaPaul J Hergenrother
March 27, 2020
ReviewOpen Access

Engineering Cellular Signal Sensors based on CRISPR-sgRNA Reconstruction Approaches

International Journal of Biological Sciences
Hengji ZhanYuchen Liu
May 4, 2020

Genetic Biosensor Design for Natural Product Biosynthesis in Microorganisms

Trends in Biotechnology
Gazi Sakir HossainMatthew Wook Chang
May 21, 2020

Light-controlled twister ribozyme with single-molecule detection resolves RNA function in time and space

Proceedings of the National Academy of Sciences of the United States of America
Arthur KormanSarah A Woodson
April 5, 2020
Open Access

Comprehensive sequence-to-function mapping of cofactor-dependent RNA catalysis in the glmS ribozyme

Nature Communications
Johan O L AndreassonWilliam J Greenleaf

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