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Risk for Schizophrenia

Risk for Schizophrenia  diagram by undefined

Schizophrenia is a complex disease and emerging studies have identified hundreds of genetic loci harbouring schizophrenia-associated variants. These variants can potentially increase the risk for developing Schizophrenia. Discover the latest research on Risk For Schizophrenia here.

Top 20 most recent papers
bioRxiv

Genome-wide association study identifies 49 common genetic variants associated with handedness.

bioRxivNovember 7, 2019
Gabriel Cuellar PartidaSarah Elizabeth Medland
92
Cell

Genetic Control of Expression and Splicing in Developing Human Brain Informs Disease Mechanisms

CellOctober 17, 2019
Rebecca L WalkerDaniel H. Geschwind
91
1
bioRxiv

Insights into the aetiology of snoring from observational and genetic investigations in the UK Biobank (n=408,317)

bioRxivOctober 17, 2019
Adrian I CamposMiguel E. Renteria
15
bioRxiv

Subthreshold psychosis symptoms associated with molecular genetic risk in a population-based cohort: Findings from Generation Scotland

bioRxivOctober 28, 2019
Anna R. DochertyKenneth Seedman Kendler
9
Molecular Psychiatry

Bipolar multiplex families have an increased burden of common risk variants for psychiatric disorders

Molecular PsychiatryNovember 11, 2019
Till F. M. AndlauerMarcella Rietschel
9
bioRxiv

GluD1 knockout mice with a pure C57BL/6N background show impaired fear memory, social interaction, and enhanced depressive-like behavior

bioRxivOctober 31, 2019
Chihiro NakamotoKenji Sakimura
2
Translational Psychiatry

Genetic risk scores for major psychiatric disorders and the risk of postpartum psychiatric disorders

Translational PsychiatryNovember 11, 2019
Anna E BauerSamantha E Meltzer-Brody
15
The American Journal of Psychiatry

Polygenic Risk Score Contribution to Psychosis Prediction in a Target Population of Persons at Clinical High Risk

The American Journal of PsychiatryNovember 12, 2019
Diana O. PerkinsScott W. Woods
33
Scientific Reports

Differential protein expression of DARPP-32 versus Calcineurin in the prefrontal cortex and nucleus accumbens in schizophrenia and bipolar disorder

Scientific ReportsOctober 16, 2019
Yasuto KuniiHirooki Yabe
bioRxiv

Leveraging correlations between polygenic risk score predictors to detect heterogeneity in GWAS cohorts

bioRxivNovember 1, 2019
Jie YuanItsik Pe'er
33
bioRxiv

Decoding the multimorbidities among psychiatric disorders and cognitive functioning

bioRxivNovember 11, 2019
Evgeniia GolovinaJustin Martin O'Sullivan
16
Translational Psychiatry

1,25-Dihydroxyvitamin D modulates L-type voltage-gated calcium channels in a subset of neurons in the developing mouse prefrontal cortex

Translational PsychiatryNovember 11, 2019
Helen GoochJohn Joseph McGrath
2
Molecular Psychiatry

The genome-wide risk alleles for psychiatric disorders at 3p21.1 show convergent effects on mRNA expression, cognitive function, and mushroom dendritic spine

Molecular PsychiatryNovember 13, 2019
Zhi-Hui YangXiao Xiao
Nature Genetics

The impact of short tandem repeat variation on gene expression

Nature GeneticsNovember 1, 2019
Stephanie Feupe FotsingMelissa Gymrek
169
5
Translational Psychiatry

Examining the association between genetic liability for schizophrenia and psychotic symptoms in Alzheimer's disease

Translational PsychiatryOctober 22, 2019
Byron CreeseAddNeuroMed consortium and the Alzheimer’s Disease Neuroimaging Initiative
43
1
The European Respiratory Journal

Shared Genetics of Asthma and Mental Health Disorders: A Large-Scale Genome-Wide Cross-Trait Analysis

The European Respiratory JournalOctober 17, 2019
Zhaozhong ZhuLi-Ming Liang
8
Progress in Neuro-psychopharmacology & Biological Psychiatry

Identification of relevant hub genes for early intervention at gene coexpression modules with altered predicted expression in schizophrenia

Progress in Neuro-psychopharmacology & Biological PsychiatryNovember 9, 2019
Julio A Rodriguez-LopezJavier C Costas
5
The Pharmacogenomics Journal

A functional HTR1A polymorphism, rs6295, predicts short-term response to lurasidone: confirmation with meta-analysis of other antipsychotic drugs

The Pharmacogenomics JournalOctober 21, 2019
Akane YoshikawaHerbert Yale Meltzer
3
Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences

Investigating genetic links between grapheme-colour synaesthesia and neuropsychiatric traits

Philosophical Transactions of the Royal Society of London. Series B, Biological SciencesOctober 22, 2019
Amanda K TilotSimon E. Fisher
10
The Journal of Comparative Neurology

Characterization of striatal phenotypes in heterozygous Disc1 mutant mice, a model of haploinsufficiency

The Journal of Comparative NeurologyNovember 13, 2019
Baskaran RathinasamyLi-Jen Lee

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