Feed Preview

Risk for Schizophrenia

Risk for Schizophrenia  diagram by undefined

Schizophrenia is a complex disease and emerging studies have identified hundreds of genetic loci harbouring schizophrenia-associated variants. These variants can potentially increase the risk for developing Schizophrenia. Discover the latest research on Risk For Schizophrenia here.

Top 20 most recent papers

Genome-wide association study identifies 49 common genetic variants associated with handedness.

bioRxivNovember 7, 2019
Gabriel Cuellar PartidaSarah Elizabeth Medland

Genetic Control of Expression and Splicing in Developing Human Brain Informs Disease Mechanisms

CellOctober 17, 2019
Rebecca L WalkerDaniel H. Geschwind

Insights into the aetiology of snoring from observational and genetic investigations in the UK Biobank (n=408,317)

bioRxivOctober 17, 2019
Adrian I CamposMiguel E. Renteria

Subthreshold psychosis symptoms associated with molecular genetic risk in a population-based cohort: Findings from Generation Scotland

bioRxivOctober 28, 2019
Anna R. DochertyKenneth Seedman Kendler
Molecular Psychiatry

Bipolar multiplex families have an increased burden of common risk variants for psychiatric disorders

Molecular PsychiatryNovember 11, 2019
Till F. M. AndlauerMarcella Rietschel

GluD1 knockout mice with a pure C57BL/6N background show impaired fear memory, social interaction, and enhanced depressive-like behavior

bioRxivOctober 31, 2019
Chihiro NakamotoKenji Sakimura
Translational Psychiatry

Genetic risk scores for major psychiatric disorders and the risk of postpartum psychiatric disorders

Translational PsychiatryNovember 11, 2019
Anna E BauerSamantha E Meltzer-Brody
The American Journal of Psychiatry

Polygenic Risk Score Contribution to Psychosis Prediction in a Target Population of Persons at Clinical High Risk

The American Journal of PsychiatryNovember 12, 2019
Diana O. PerkinsScott W. Woods
Scientific Reports

Differential protein expression of DARPP-32 versus Calcineurin in the prefrontal cortex and nucleus accumbens in schizophrenia and bipolar disorder

Scientific ReportsOctober 16, 2019
Yasuto KuniiHirooki Yabe

Leveraging correlations between polygenic risk score predictors to detect heterogeneity in GWAS cohorts

bioRxivNovember 1, 2019
Jie YuanItsik Pe'er

Decoding the multimorbidities among psychiatric disorders and cognitive functioning

bioRxivNovember 11, 2019
Evgeniia GolovinaJustin Martin O'Sullivan
Translational Psychiatry

1,25-Dihydroxyvitamin D modulates L-type voltage-gated calcium channels in a subset of neurons in the developing mouse prefrontal cortex

Translational PsychiatryNovember 11, 2019
Helen GoochJohn Joseph McGrath
Molecular Psychiatry

The genome-wide risk alleles for psychiatric disorders at 3p21.1 show convergent effects on mRNA expression, cognitive function, and mushroom dendritic spine

Molecular PsychiatryNovember 13, 2019
Zhi-Hui YangXiao Xiao
Nature Genetics

The impact of short tandem repeat variation on gene expression

Nature GeneticsNovember 1, 2019
Stephanie Feupe FotsingMelissa Gymrek
Translational Psychiatry

Examining the association between genetic liability for schizophrenia and psychotic symptoms in Alzheimer's disease

Translational PsychiatryOctober 22, 2019
Byron CreeseAddNeuroMed consortium and the Alzheimer’s Disease Neuroimaging Initiative
The European Respiratory Journal

Shared Genetics of Asthma and Mental Health Disorders: A Large-Scale Genome-Wide Cross-Trait Analysis

The European Respiratory JournalOctober 17, 2019
Zhaozhong ZhuLi-Ming Liang
Progress in Neuro-psychopharmacology & Biological Psychiatry

Identification of relevant hub genes for early intervention at gene coexpression modules with altered predicted expression in schizophrenia

Progress in Neuro-psychopharmacology & Biological PsychiatryNovember 9, 2019
Julio A Rodriguez-LopezJavier C Costas
The Pharmacogenomics Journal

A functional HTR1A polymorphism, rs6295, predicts short-term response to lurasidone: confirmation with meta-analysis of other antipsychotic drugs

The Pharmacogenomics JournalOctober 21, 2019
Akane YoshikawaHerbert Yale Meltzer
Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences

Investigating genetic links between grapheme-colour synaesthesia and neuropsychiatric traits

Philosophical Transactions of the Royal Society of London. Series B, Biological SciencesOctober 22, 2019
Amanda K TilotSimon E. Fisher
The Journal of Comparative Neurology

Characterization of striatal phenotypes in heterozygous Disc1 mutant mice, a model of haploinsufficiency

The Journal of Comparative NeurologyNovember 13, 2019
Baskaran RathinasamyLi-Jen Lee

See more papers from this feed

Related Feeds

Antipsychotic Drugs

Antipsychotic drugs are a class of medication primarily used to manage psychosis (including delusions, hallucinations, paranoia or disordered thought), principally in schizophrenia and bipolar disorder. Discover the latest research on antipsychotic drugs here

Antipsychotic-Induced Weight Gain

Antipsychotic-induced weight gain (aiwg) is a common adverse effect of this treatment, particularly with second-generation antipsychotics, and it is a major health problem around the world. Here are the latest discoveries pertaining to AIWG.


Catatonia is a psychomotor syndrome with motor and behavioral symptoms, and can occur in both patients with or without psychiatric illness. Discover the latest research on Catatonia here.

Catatonic Schizophrenia

Catatonia is a psychomotor symptom in which patients present with stupor, although catatonic excitement may also present at the other end of the spectrum. Catatonia has been historically associated with schizophrenia although it is also associated with other neuropsychiatric disorders. Find the latest research on catatonic schizophrenia here.

Comorbidity In Psychiatry

There is ongoing debate regarding the handling of comorbidity in psychiatric disorders, and determining whether the issue lies with the categorizations of diagnostic conventions or if there is an underlying pathology that links multiple diseases. Understanding how to give the proper diagnosis/diagnoses would allow for optimal management of the patient. Find the latest research on comorbidity in psychiatry here.

Epigenetics & Psychiatry

Psychiatric disorders are known to be multifaceted in their pathophysiology. Because epigenetic changes can be sensitive to the environment, inherited, and reversible, the study of epigenetics in psychiatric disease is a logical way to understand the natural history of the disease as well as to develop therapeutics. Find the latest research on epigenetics and psychiatry here.

Forensic Psychiatry

Forensic psychiatry includes the relationship between psychiatric abnormalities and legal violations and crimes. Discover the latest research on forensic psychiatry here.

Inflammation and Immunity in Schizophrenia

Schizophrenia is a complex mental disease caused by a combination of serial alterations in genetic and environmental factors, including inflammation and immunity. Here is the latest research.


Neuropsychiatry is an emerging field at the intersection of neurology and psychiatry, driven by the unprecedented advances in neuroscience. Here are the latest discoveries in neuropsychiatry.

Paranoid Disorders

Paranoid disorders are psychiatric disorders with the suspicion and belief that others are plotting against them, leading to mistrust of others. These symptoms of paranoia can be seen in other psychiatric disorders including dementia and schizophrenia. Here is the latest research on paranoid disorders.

© 2019 Meta ULC. All rights reserved