RNA Helicases

RNA helicases are motor enzymes that unwind RNA and are essential for several RNA metabolism processes including ribosome biogenesis, translation initiation, and pre-mRNA splicing. Defects in RNA helicases are associated with cancers, infectious diseases, as well as neurodegenerative disorders. Here is the latest research.

April 25, 2020
ReviewOpen Access

The Complex Relationship between HTLV-1 and Nonsense-Mediated mRNA Decay (NMD)

Léa ProchassonVincent Mocquet
May 23, 2020

UAP56/DDX39B is a major cotranscriptional RNA-DNA helicase that unwinds harmful R loops genome-wide

Genes & Development
Carmen Pérez-CaleroAndrés Aguilera
May 21, 2020
Open Access

SARS, MERS and SARS-CoV-2 (COVID-19) treatment: a patent review

Expert Opinion on Therapeutic Patents
José Adão Carvalho Nascimento JuniorMairim Russo Serafini
May 18, 2020

MiR-26 regulates ddx3x expression in medaka (Oryzias latipes) gonads

Comparative Biochemistry and Physiology. Part B, Biochemistry & Molecular Biology
Lulu SunMingyou Li
May 13, 2020

SUMOylation of DDX39A Alters Binding and Export of Antiviral Transcripts to Control Innate Immunity

The Journal of Immunology : Official Journal of the American Association of Immunologists
Peidian ShiJinhai Huang
May 15, 2020
Open Access

Decoding the vital segments in human ATP-dependent RNA helicase

Vandana KamjulaAshish Runthala
April 22, 2020
Open Access

The mRNA encoding the JUND tumor suppressor detains nuclear RNA-binding proteins to assemble polysomes that are unaffected by mTOR

The Journal of Biological Chemistry
Gatikrushna SinghKathleen Boris-Lawrie
May 21, 2020
Open Access

Crystal structure of the NS3-like helicase from Alongshan virus

Xiaopan GaoSheng Cui
April 2, 2020

RNA helicase DDX21 mediates nucleotide stress responses in neural crest and melanoma cells

Nature Cell Biology
Cristina SantorielloLeonard I Zon
May 19, 2020

Proteomic analysis of Trypanosoma cruzi spliceosome complex

Journal of Proteomics
Rosicler L BarbosaPatricia P Coltri
April 16, 2020

Generation of B6-Ddx4em1(CreERT2)Utr , a novel CreERT2 knock-in line, for germ cell lineage by CRISPR/Cas9

Genesis : the Journal of Genetics and Development
Hoai Thu LeFumihiro Sugiyama
April 25, 2020
ReviewOpen Access

Discrete roles of RNA helicases in human male germline and spermatogenesis

Journal of Applied Genetics
Katarzyna Tutak, Natalia Rozwadowska
May 7, 2020
Open Access

GCN2-Like Kinase Modulates Stress Granule Formation During Nutritional Stress in Trypanosoma cruzi

Frontiers in Cellular and Infection Microbiology
Amaranta Muniz MalvezziSergio Schenkman
May 29, 2020

Mapping domains of ARS2 critical for its RNA decay capacity

Nucleic Acids Research
Mireille MelkoTorben Heick Jensen

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