RNA-mediated Toxicity in Neurodegeneration

Some neurodegenerative disorders are believed to be due to RNA-induced cellular toxicity caused by the expansion of nucleotide-repeat sequences in DNA. Discover the latest research on RNA-mediated toxicity in neurodegeneration here.

December 4, 2020
Open Access

Myricetin reduces cytotoxicity by suppressing hepcidin expression in MES23.5 cells

Neural Regeneration Research
Han DengZe-Gang Ma
December 18, 2020
Open Access

Alzheimer's, Parkinson's Disease and Amyotrophic Lateral Sclerosis Gene Expression Patterns Divergence Reveals Different Grade of RNA Metabolism Involvement

International Journal of Molecular Sciences
Maria GarofaloStella Gagliardi
January 6, 2021

Melatonin abated Bisphenol A-induced neurotoxicity via p53/PUMA/Drp-1 signaling

Environmental Science and Pollution Research International
Ayesha IshtiaqIram Murtaza
December 16, 2020

Overexpression of D-amino acid oxidase prevents retinal neurovascular pathologies in diabetic rats

Haiyan JiangShengzhou Wu
December 17, 2020
Open Access

Synergistic effects of miR-708-5p and miR-708-3p accelerate the progression of osteoporosis

The Journal of International Medical Research
Ruran WangShengnan Huang
December 8, 2020

Effect of fibroblast growth factor 2 on degenerative endplate chondrocyte: From anabolism to catabolism.

Experimental and Molecular Pathology
Hua SongWeidong Mu
January 3, 2021

Plant miR171 modulates mTOR pathway in HEK293 cells by targeting GNA12

Molecular Biology Reports
Angelo GismondiAntonella Canini
December 2, 2020

Clinical features and molecular genetics of patients with ABCA4-retinal dystrophies

Acta Ophthalmologica
Josephine Prener HoltanRagnheiður Bragadóttir
December 6, 2020
Open Access

An inducible glycogen synthase-1 knockout halts but does not reverse Lafora disease progression in mice

The Journal of Biological Chemistry
Silvia NitschkeBerge A Minassian
December 21, 2020
Open Access

Walking the line: mechanisms underlying directional mRNA transport and localisation in neurons and beyond

Cellular and Molecular Life Sciences : CMLS
Reem Abouward, Giampietro Schiavo
January 9, 2021
Open Access

Simvastatin Influences Selected Aspects of Duchenne Muscular Dystrophy Pathology in a Mouse Model

Olga MuchaAgnieszka Łoboda
December 8, 2020
Open Access

The Role of HDAC6 in TDP-43-Induced Neurotoxicity and UPS Impairment

Frontiers in Cell and Developmental Biology
Shinrye LeeHyung-Jun Kim
November 2, 2020

Astaxanthin protects retinal ganglion cells from acute glaucoma via the Nrf2/HO-1 pathway

Journal of Chemical Neuroanatomy
Yan LiShu Liu
January 3, 2021

Metformin ameliorates the status epilepticus- induced hippocampal pathology through possible mTOR modulation

Sree Lalitha BojjaRanjana W Minz
December 16, 2020
Open Access

Reducing LncRNA-5657 expression inhibits the brain inflammatory reaction in septic rats

Neural Regeneration Research
Yi-An ZhanKe-Jian Qian
October 31, 2020
Open Access

Botanical Drug Puerarin Promotes Neuronal Survival and Neurite Outgrowth against MPTP/MPP+ -Induced Toxicity via Progesterone Receptor Signaling

Oxidative Medicine and Cellular Longevity
Yingke ZhaoJianhui Rong

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