RNA & Mitochondrial Dysfunction

Mitochondrial DNA mutations and resulting RNA transcripts that cause mitochondrial dysfunction are responsible for a wide spectrum of human diseases, referred to as mitochondrial diseases. Discover the latest research here.

January 21, 2022

KIFC1 regulates the trajectory of neuronal migration.

The Journal of Neuroscience : the Official Journal of the Society for Neuroscience
Hemalatha MuralidharanPeter W Baas
January 20, 2022

Mutation in senataxin alters the mechanism of R-loop resolution in amyotrophic lateral sclerosis 4.

Brain : a Journal of Neurology
Annapoorna KannanLaxman Gangwani
January 16, 2022

Liraglutide prevents high glucose induced HUVECs dysfunction via inhibition of PINK1/Parkin-dependent mitophagy.

Molecular and Cellular Endocrinology
Yikai ZhangChao Zheng
January 14, 2022

Mitochondrial RNA processing defect caused by a SUPV3L1 mutation in two siblings with a novel neurodegenerative syndrome.

Journal of Inherited Metabolic Disease
S L van EsveldJ N Spelbrink
January 14, 2022

Testing of the therapeutic efficacy and safety of AMPA receptor RNA aptamers in an ALS mouse model.

Life Science Alliance
Megumi AkamatsuShin Kwak
January 14, 2022
Open Access

Sublethal enteroviral infection exacerbates disease progression in an ALS mouse model.

Journal of Neuroinflammation
Yuan Chao XueHonglin Luo
January 12, 2022
Preprint
Open Access

Efficient generation of lower induced Motor Neurons by coupling Ngn2 expression with developmental cues

BioRxiv : the Preprint Server for Biology
Francesco LimoneK. Eggan
January 12, 2022
Open Access

Multi-Omics Profiling in Marfan Syndrome: Further Insights into the Molecular Mechanisms Involved in Aortic Disease.

International Journal of Molecular Sciences
Judith M A VerhagenErwin Brosens
January 12, 2022

piRNA/PIWI Protein Complex as a Potential Biomarker in Sporadic Amyotrophic Lateral Sclerosis.

Molecular Neurobiology
Rehab F AbdelhamidSeiichi Nagano
January 11, 2022

Kennedy's Disease: A Second Genetically Confirmed Report from India.

Annals of Indian Academy of Neurology
Rutul ShahPooja Mailankody
January 11, 2022
Review
Open Access

Proteinopathies as Hallmarks of Impaired Gene Expression, Proteostasis and Mitochondrial Function in Amyotrophic Lateral Sclerosis.

Frontiers in Neuroscience
Bridget C BensonGuillaume M Hautbergue

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