RNA & Tau in Frontotemporal Dementia

Tau mutations in frontotemporal dementia and parkinsonism linked to chromosome 17 (ftdp-17) are associated with changes in alternative RNA splicing. Here is the latest research on RNA & Tau in Frontotemporal Dementia.

January 17, 2021
Open Access

Modelling the cascade of biomarker changes in GRN -related frontotemporal dementia

Journal of Neurology, Neurosurgery, and Psychiatry
Jessica L PanmanGENFI consortium investigators
December 24, 2020

FUS regulates autophagy by mediating the transcription of genes critical to the autophagosome formation

Journal of Neurochemistry
Alexandra ArenasHaining Zhu
January 16, 2021
Review

FUS and TDP-43 Phases in Health and Disease

Trends in Biochemical Sciences
Bede PortzJames Shorter
January 18, 2021
Open Access

Clearance of intracellular tau protein from neuronal cells via VAMP8-induced secretion.

The Journal of Biological Chemistry
Julie PilliodNicole Leclerc
January 13, 2021

Clinical and Neuroimaging Aspects of Familial Frontotemporal Lobar Degeneration Associated with MAPT and GRN Mutations

Advances in Experimental Medicine and Biology
Bradley F Boeve, Howard Rosen
January 9, 2021
Open Access

Exifone Is a Potent HDAC1 Activator with Neuroprotective Activity in Human Neuronal Models of Neurodegeneration

ACS Chemical Neuroscience
Debasis PatnaikStephen J Haggarty
January 12, 2021
Review
Open Access

Matrin 3 in neuromuscular disease: physiology and pathophysiology

JCI Insight
Ahmed M Malik, Sami J Barmada
January 13, 2021

Trends in Understanding the Pathological Roles of TDP-43 and FUS Proteins

Advances in Experimental Medicine and Biology
Emanuele Buratti
January 8, 2021
Preprint
Open Access

Enhanced detection of nucleotide repeat mRNA with hybridization chain reaction

BioRxiv : the Preprint Server for Biology
M. R. GlineburgPeter Todd
January 18, 2021
Open Access

FUS contributes to mTOR-dependent inhibition of translation

The Journal of Biological Chemistry
Myriam SévignyChantelle F Sephton
December 21, 2020

Genetic determinants of survival in progressive supranuclear palsy: a genome-wide association study

Lancet Neurology
Edwin JabbariPSP Genetics Group
December 22, 2020
Case Report
Open Access

A Specific Diplotype H1j/H2 of the MAPT Gene Could Be Responsible for Parkinson's Disease with Dementia

Case Reports in Genetics
Imane SmailiAhmed Bouhouche
January 19, 2021
Preprint
Open Access

Cholinergic signalling in the forebrain controls microglial phenotype and responses to systemic inflammation

BioRxiv : the Preprint Server for Biology
A. NazmiColm Cunningham
January 9, 2021
Open Access

Induction of autophagy mitigates TDP-43 pathology and translational repression of neurofilament mRNAs in mouse models of ALS/FTD

Molecular Neurodegeneration
Sunny KumarJean-Pierre Julien

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