RNA & Tau in Frontotemporal Dementia

Tau mutations in frontotemporal dementia and parkinsonism linked to chromosome 17 (ftdp-17) are associated with changes in alternative RNA splicing. Here is the latest research on RNA & Tau in Frontotemporal Dementia.

January 15, 2022
Preprint
Open Access

Comprehensive preclinical evaluation of human-derived anti-poly-GA antibodies in cellular and animal models of C9ORF72 disease

BioRxiv : the Preprint Server for Biology
M. JambeauClotilde La
January 15, 2022
Case Report

Diffuse Lewy body disease presenting as Parkinson's disease with progressive aphasia.

Neuropathology : Official Journal of the Japanese Society of Neuropathology
Shunsuke KogaDennis W Dickson
January 13, 2022

MAPT Q336H mutation: intra-familial phenotypic heterogeneity in a new Italian family.

European Journal of Neurology : the Official Journal of the European Federation of Neurological Societies
Cristina VillaPaola Caroppo
January 4, 2022

Reduced mtDNA Copy Number in the Prefrontal Cortex of C9ORF72 Patients.

Molecular Neurobiology
Maria Isabel Alvarez-MoraLaia Rodriguez-Revenga
January 3, 2022
Review
Open Access

DNA Damage and Repair Deficiency in ALS/FTD-Associated Neurodegeneration: From Molecular Mechanisms to Therapeutic Implication.

Frontiers in Molecular Neuroscience
Haibo WangMuralidhar L Hegde
December 31, 2021

Testing the neuroinflammatory role of tau-induced transposable elements in tauopathy.

Alzheimer's & Dementia : the Journal of the Alzheimer's Association
Elizabeth Ochoa ThomasBess Frost
December 31, 2021

Defective proteostasis in patient-derived iPSC-astrocytes and neurons carrying a MAPT IVS10+16 mutation.

Alzheimer's & Dementia : the Journal of the Alzheimer's Association
Sidhartha Mahali, Celeste M Karch
December 31, 2021

Autophagy and lysosomal defects in cells expressing disease-associated tau.

Alzheimer's & Dementia : the Journal of the Alzheimer's Association
Saskia J PollackDiane P Hanger
December 31, 2021

Impact of MAPT mutations on transcriptomic signatures of FTLD brains and patient-derived pluripotent cell models.

Alzheimer's & Dementia : the Journal of the Alzheimer's Association
Miguel MinayaCeleste M Karch
December 31, 2021

Investigating circular RNA-mediated neurotoxicity in tauopathies.

Alzheimer's & Dementia : the Journal of the Alzheimer's Association
Farzaneh AtrianBess Frost
December 31, 2021

Investigating changes in the proteostasis capabilities of iPSC-neurons during development and in FTD using iPSC-neurons with MAPT mutations.

Alzheimer's & Dementia : the Journal of the Alzheimer's Association
Georgie LinesSelina Wray
December 30, 2021

Immunotherapeutic Approaches for the Treatment of Neurodegenerative Diseases: Challenges and Outcomes.

CNS & Neurological Disorders Drug Targets
Sushma, Amal Chandra Mondal
December 28, 2021

A Pathway-Specific Polygenic Risk Score is Associated with Tau Pathology and Cognitive Decline.

Journal of Alzheimer's Disease : JAD
Yuqing SunAlzheimer’s Disease Neuroimaging Initiative

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