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RNAi & Gene Silencing

RNAi & Gene Silencing diagram by ellepigrafica, Shutterstock
ellepigrafica, Shutterstock

RNA Interference (RNAi) pathway is involved in post-transcriptional gene silencing, transcriptional silencing and epigenetic silencing as well as its use as a tool for forward genetics and therapeutics. Discover the latest research here.

Top 20 most recent papers

Lineage reversion drives WNT independence in intestinal cancer

bioRxivJanuary 23, 2020
Teng HanLukas E Dow
Wiley Interdisciplinary Reviews. RNA

Understanding and targeting the disease-related RNA binding protein human antigen R (HuR)

Wiley Interdisciplinary Reviews. RNAJanuary 24, 2020
Christopher W SchultzJonathan R Brody
Experimental Cell Research

A role for ceramide glycosylation in resistance to oxaliplatin in colorectal cancer

Experimental Cell ResearchJanuary 24, 2020
James P MadiganDaniel W Rosenberg

High-throughput screens of PAM-flexible Cas9 variants for gene knock-out and transcriptional modulation

bioRxivJanuary 23, 2020
Mateusz LegutNeville E Sanjana

RBMS1 suppresses colon cancer metastasis through targeted stabilization of its mRNA regulon

bioRxivJanuary 23, 2020
Johnny YuHani Goodarzi
ACS Chemical Biology

Identification of interferon receptor IFNAR2 as a novel HCV entry factor by using chemical probes

ACS Chemical BiologyJanuary 24, 2020
Jie QingZhiyong Lou
Frontiers in Genetics

Aberrantly High Levels of Somatic LINE-1 Expression and Retrotransposition in Human Neurological Disorders

Frontiers in GeneticsJanuary 24, 2020
Diane M Terry, Scott E Devine
Journal of Virology

Phosphosite analysis of the cytomegaloviral mRNA export factor pUL69 reveals serines with critical importance for recruitment of cellular proteins Pin1 and UAP56/URH49

Journal of VirologyJanuary 24, 2020
Marco ThomasThomas Stamminger
Cell Systems

Gene Regulatory Strategies that Decode the Duration of NFκB Dynamics Contribute to LPS- versus TNF-Specific Gene Expression

Cell SystemsJanuary 24, 2020
Supriya SenAlexander Hoffmann
Journal of Virology

Kaposi's Sarcoma Associated Herpesvirus Infection Induces the Expression of Neuroendocrine Genes in Endothelial Cells

Journal of VirologyJanuary 24, 2020
Mohanan Valiya VeettilBala Chandran
Journal of Insect Physiology

Methoprene-tolerant is essential for embryonic development of the red flour beetle Tribolium castaneum

Journal of Insect PhysiologyJanuary 24, 2020
Shouya NaruseChieka Minakuchi
PloS One

HIV antiretroviral drugs, dolutegravir, maraviroc and ritonavir-boosted atazanavir use different pathways to affect inflammation, senescence and insulin sensitivity in human coronary endothelial cells

PloS OneJanuary 24, 2020
Martine AuclairJacqueline Capeau
Journal of Controlled Release : Official Journal of the Controlled Release Society

Co-delivery of p38α MAPK and p65 siRNA by novel liposomal glomerulus-targeting nano carriers for effective immunoglobulin a nephropathy treatment

Journal of Controlled Release : Official Journal of the Controlled Release SocietyJanuary 24, 2020
Yuanfang WangLing Zhang
Biochemical Pharmacology

Curcumin induces stabilization of Nrf2 protein through Keap1 cysteine modification

Biochemical PharmacologyJanuary 24, 2020
Jun-Wan ShinYoung-Joon Surh
G3 : Genes - Genomes - Genetics

Genetic Basis of Increased Lifespan and Postponed Senescence in Drosophila melanogaster

G3 : Genes - Genomes - GeneticsJanuary 24, 2020
Grace A ParkerTrudy F C Mackay
Current Molecular Medicine

Ursodeoxycholic acid (UDCA) promotes lactate metabolism in mouse hepatocytes through cholic acid (CA) - farnesoid X receptor (FXR) pathway

Current Molecular MedicineJanuary 24, 2020
Lu WangYun Long
Journal of Cellular Physiology

IFN-γ/mTORC1 decreased Rab11 in Schwann cells of diabetic peripheral neuropathy, inhibiting cell proliferation via GLUT1 downregulation

Journal of Cellular PhysiologyJanuary 24, 2020
Wei DuJun Hao
RNA Biology

Transcriptome-wide-scale-predicted dsRNAs potentially involved in RNA homeostasis are remarkably excluded from genes with no/very low expression in all developmental stages

RNA BiologyJanuary 24, 2020
Claude PasquierAlain Robichon
Developmental and Comparative Immunology

Environmental rearing conditions are key determinants of changes in immune gene expression patterns in shrimp midgut

Developmental and Comparative ImmunologyJanuary 24, 2020
Mariana Rangel PilottoLuciane Maria Perazzolo
Computational and Structural Biotechnology Journal

Inhibition of protein FAK enhances 5-FU chemosensitivity to gastric carcinoma via p53 signaling pathways

Computational and Structural Biotechnology JournalJanuary 24, 2020
Jingjing HouYongsheng Yu

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