ROS: Metabolism & Signaling in Neurodegeneration

Reactive oxygen species (ROS) are reactive chemicals containing oxygen which may have complex roles in promoting the development of neurodegenerative diseases. They are generated as a byproduct of oxidative energy metabolism and play a role in regulating several intracellular signaling pathways. Here is the latest research on ROS metabolism and signaling in neurodegeneration.

January 16, 2021
Review

Oxidopamine and oxidative stress: recent advances in experimental physiology and pharmacology

Chemico-biological Interactions
Igor PanticClaude Brodski
January 6, 2021

Melatonin abated Bisphenol A-induced neurotoxicity via p53/PUMA/Drp-1 signaling

Environmental Science and Pollution Research International
Ayesha IshtiaqIram Murtaza
January 15, 2021

Potential therapeutic effects of Nrf2 activators on intracranial hemorrhage

Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism
Takahiko ImaiHideaki Hara
January 9, 2021
Open Access

Presence of a mutation in PSEN1 or PSEN2 gene is associated with an impaired brain endothelial cell phenotype in vitro

Fluids and Barriers of the CNS
Snehal RautAbraham J Al-Ahmad
January 12, 2021
Review
Open Access

Angiotensin Type 2 Receptors: Painful, or Not?

Frontiers in Pharmacology
Lakshmi Pulakat, Colin Sumners
January 9, 2021
Review
Open Access

The Neuroprotective Effect of Irisin in Ischemic Stroke

Frontiers in Aging Neuroscience
Yaqiang LiuChaoyue Meng
January 12, 2021

Erythrocytes as a preferential target of oxidative stress in blood

Free Radical Research
Junichi FujiiMalay B Mukherjee
January 12, 2021
Review
Open Access

Iron Metabolism and Ferroptosis in Epilepsy

Frontiers in Neuroscience
Shuang ChenQifu Li
January 14, 2021
Open Access

Antioxidative Effects of Chrysoeriol via Activation of the Nrf2 Signaling Pathway and Modulation of Mitochondrial Function

Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry
Myung Hee KimDae Yu Kim
January 10, 2021

SOX21-AS1 modulates neuronal injury of MMP+ -treated SH-SY5Y cells via targeting miR-7-5p and inhibiting IRS2

Neuroscience Letters
Yang XieZuoxiao Li
January 12, 2021
Open Access

Doxycycline inhibits α-synuclein-associated pathologies in vitro and in vivo

Neurobiology of Disease
Antonio Dominguez-MeijideTiago Fleming Outeiro
January 17, 2021
Open Access

Oxidative Stress Underlies the Ischemia/Reperfusion-Induced Internalization and Degradation of AMPA Receptors

International Journal of Molecular Sciences
Lindsay M AchzetDarrell A Jackson
January 10, 2021
Review
Open Access

The Mitochondrial Permeability Transition: Nexus of Aging, Disease and Longevity

Cells
Hagai Rottenberg, Jan B Hoek

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