RPGRIP1L Gene & Neurons

RPGRIP1L is a ciliary gene that is ubiquitously expressed in human embryonic and fetal tissues. It functions in neurodevelopment, including the development of hypothalamic arcuate neurons. Defects in this gene are associated with Joubert syndrome (type 7) and Meckel syndrome (type 5). Here is the latest research on the role of this gene in neurons.

April 17, 2021

Adenosine 5'-monophosphate induces hypothermia and alters gene expressions in the brain and liver of chicks.

Brain Research Bulletin
Yoshimitsu OuchiTakashi Bungo
April 16, 2021

The N-terminal Leu-Pro-Gln sequence of Rab34 is required for ciliogenesis in hTERT-RPE1 cells.

Small GTPases
Mai E OguchiMitsunori Fukuda
April 16, 2021

Structure reveals the activation mechanism of the MC4 receptor to initiate satiation signaling.

Science
Hadar IsraeliMoran Shalev-Benami
April 16, 2021

The BBSome: a nexus controlling energy metabolism in the brain.

The Journal of Clinical Investigation
Sandra Blaess, Dagmar Wachten
April 14, 2021
Open Access

Insulin within the Arcuate Nucleus Has Paradoxical Effects on Nociception in Healthy and Diabetic Rats.

Basic and Clinical Neuroscience
Hossein Khaleghzadeh-AhangarAliakbar Moghadamnia
April 14, 2021
Review
Open Access

STAT3 phosphorylation in central leptin resistance.

Nutrition & Metabolism
Huimin LiuGuoqing Yang
April 14, 2021

A gut-intrinsic melanocortin signalling complex augments L cell secretion in humans.

Gastroenterology
E W SunD J Keating
April 12, 2021

Primary cilia and the DNA damage response: linking a cellular antenna and nuclear signals.

Biochemical Society Transactions
Ciaran G Morrison
April 11, 2021

The daily gene transcription cycle in mouse retina.

Experimental Eye Research
Zhijie WangShibo Tang
April 8, 2021
Open Access

Lipocalin 2 mediates appetite suppression during pancreatic cancer cachexia.

Nature Communications
Brennan OlsonDaniel L Marks
April 8, 2021

Transgenerational effects of polychlorinated biphenyls: 2. Hypothalamic gene expression in rats.

Biology of Reproduction
Andrea C GoreJan A Mennigen
April 10, 2021

Paraventricular Calcitonin Receptor Expressing Neurons Modulate Energy Homeostasis in Male Mice.

Endocrinology
Ian E GonzalezDavid P Olson
April 8, 2021
Open Access

Melanocortin 3 receptor-expressing neurons in the ventromedial hypothalamus promote glucose disposal.

Proceedings of the National Academy of Sciences of the United States of America
Amy K SuttonDavid P Olson
April 8, 2021
Review
Open Access

Fibrocystic liver disease: novel concepts and translational perspectives.

Translational Gastroenterology and Hepatology
Alberto LasagniMario Strazzabosco

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