The SARS-CoV-2 virus enters the human host cell via the receptor ACE2 and uses the serine protease TMPRSS2 for S protein priming. The ACE2 usage has been shown to be crucial for transmissibility of other coronaviruses. Much research into the COVID-19 pandemic focuses on understanding the complex process of virus entry.
Artificial intelligence (AI) offers a powerful new tool that could potentially be instrumental in controling and managing the SARS-CoV-2 virus. The papers in this feed report on the applications of AI to the current pandemic, which may be able to predict the location of the next outbreak, or facilitate new drug design.
Acute viral rhinopharyngitis, also known as "common cold", is an acute, self-limiting viral infection of the upper respiratory tract involving the nose, sinuses, pharynx and larynx. Discover the latest research on acute viral rhinopharyngitis here.
Aspergillosis is the name given to a wide variety of diseases caused by infection by fungi of the genus Aspergillus. Aspergillosis occurs in chronic or acute forms which are clinically very distinct. Most cases of acute aspergillosis occur in patients with severely compromised immune systems. Chronic colonization or infection can cause complications in people with underlying respiratory illnesses. Discover the latest research on aspergillosis here.
Bacterial pneumonia is a prevalent and costly infection that is a significant cause of morbidity and mortality in patients of all ages. Here is the latest research.
Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.
Growing evidence shows that COVID-19 can result in serious complications affecting the cardiovascular system, including dysrhythmias, myocarditis, acute myocardial infarction, and heart failure. This feed follows studies investigating the effects of SARS-CoV-2 infection on the heart.
COVID-19 patients typically present with high fever and a persistent cough. This feed focuses on clinical diagnosis, including RT-PCR testing for the presence of SARS-CoV-2 and radiographic assessment of lungs.
While most COVID-19 infections cause only mild to moderate symptoms, severely affected patients, such as those presenting with pneumonia, ARDS or septic shock, require hospitalization. This feed focuses on clinical management of patients using oxygen therapy, ventilation, and other treatment strategies, and covers some medical case reports.
COVID-19 represents a particular challenge to people with serious chronic medical conditions such as diabetes, hypertension, cardiovascular disease, and chronic lung disease. Research into the intersection between comorbidities and COVID-19 is focusing on risks and treatment outcomes for these patients.
A growing number of complications associated with COVID-19 has been identified. This feed focuses primarily on cardiovascular and respiratory manifestations in severely ill patients.