Scrapie

Scrapie is one of the several transmissible spongiform encephalopathies that affect the nervous system of sheep and goats. Here is the latest research on this fatal degenerative disease.

June 21, 2020
Open Access

An astrocyte cell line that differentially propagates murine prions

The Journal of Biological Chemistry
Waqas TahirHermann M Schätzl
May 23, 2020
Open Access

Radical Change in Zoonotic Abilities of Atypical BSE Prion Strains as Evidenced by Crossing of Sheep Species Barrier in Transgenic Mice

Emerging Infectious Diseases
Alba Marín-MorenoJuan Maria Torres
May 9, 2020
Open Access

RNA-seq and network analysis reveal unique glial gene expression signatures during prion infection

Molecular Brain
James A CarrollBruce Chesebro
May 11, 2020
Review

Prions: Roles in Development and Adaptive Evolution

Journal of Molecular Evolution
Jamie D Dixson, Rajeev K Azad
June 14, 2020

Metabolomic study of disease progression in scrapie prion infected mice; validation of a novel method for brain metabolite extraction

Metabolomics : Official Journal of the Metabolomic Society
Ze-Lin FuBrian D Sykes
April 18, 2020
Open Access

Isolation of infectious, non-fibrillar and oligomeric prions from a genetic prion disease

Brain : a Journal of Neurology
Ilaria VanniRomolo Nonno
April 16, 2020
Open Access

Cofactor and glycosylation preferences for in vitro prion conversion are predominantly determined by strain conformation

PLoS Pathogens
Cassandra M BurkeSurachai Supattapone
June 19, 2020
Open Access

MicroRNA Alterations in a Tg501 Mouse Model of Prion Disease

Biomolecules
Janne Markus ToivonenInmaculada Martín-Burriel
April 22, 2020

Genetic variability following selection for scrapie resistance in six autochthonous sheep breeds in the province of Bolzano (northern Italy)

Journal of Animal Breeding and Genetics = Zeitschrift Für Tierzüchtung Und Züchtungsbiologie
Fulvio BordinAnna Granato
April 25, 2020
Review
Open Access

Using NMR spectroscopy to investigate the role played by copper in prion diseases

Neurological Sciences : Official Journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology
Rawiah A AlsiaryAbdul-Hamid Emwas
May 13, 2020

The uptake of tau amyloid fibrils is facilitated by the cellular prion protein and hampers prion propagation in cultured cells

Journal of Neurochemistry
Elena De CeccoGiuseppe Legname
June 18, 2020
Open Access

Prions from Sporadic Creutzfeldt-Jakob Disease Patients Propagate as Strain Mixtures

MBio
Hervé CassardOlivier Andréoletti

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