sGC Modulators

Soluble guanylate cyclase (sGC) stimulators and activators have been developed to treat patients with pulmonary hypertension and heart failure, respectively. Recently these sGC modulators have been explored for the treatment of fibrosis. Discover the latest research on sGC modulators here.

August 6, 2020
Open Access

PPP6C Negatively Regulates STING-Dependent Innate Immune Responses

Guoxin NiBlossom Damania
July 28, 2020
Open Access

NBS1-CtIP-Mediated DNA End Resection Regulates cGAS Binding to Micronuclei

BioRxiv : the Preprint Server for Biology
S. AbdisalaamAsaithamby Aroumougame
July 31, 2020
Open Access

Efficacy and safety of riociguat in combination therapy for patients with pulmonary arterial hypertension (PATENT studies)

Pulmonary Circulation
Hossein A GhofraniMarc Humbert
August 4, 2020
Open Access

Balloon pulmonary angioplasty for chronic thromboembolic pulmonary hypertension: State of the art

World Journal of Clinical Cases
Qi JinZhi-Hong Liu
August 10, 2020

Riociguat ameliorates kidney injury and fibrosis in an animal model

Biochemical and Biophysical Research Communications
Seereddy SravaniChandraiah Godugu
August 1, 2020
Open Access

Decorin Protects Cardiac Myocytes against Simulated Ischemia/Reperfusion Injury

Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry
Renáta GáspárAnikó Görbe
July 31, 2020
Open Access

Elevated intracellular cyclic-di-GMP level in Shewanella oneidensis increases expression of c-type cytochromes

Microbial Biotechnology
Chun Kiat NgBin Cao
July 29, 2020

Cyclic Nucleotides Signaling and Phosphodiesterase Inhibition: Defying Alzheimer's Disease

Current Drug Targets
Vivek Kumar SharmaShareen Singh
August 7, 2020
Open Access

Integrated Analysis of Hub Genes and Pathways In Esophageal Carcinoma Based on NCBI's Gene Expression Omnibus (GEO) Database: A Bioinformatics Analysis

Medical Science Monitor : International Medical Journal of Experimental and Clinical Research
Tan Yu-JingTang Biao
July 25, 2020
Open Access

Foraging gene and xenobiotic stresses relationships in Drosophila melanogaster

BioRxiv : the Preprint Server for Biology
July 27, 2020
Open Access

Vasopressor-Sparing Action of Methylene Blue in Severe Sepsis and Shock: A Narrative Review

Advances in Therapy
Filomena PuntilloGiustino Varrassi
August 2, 2020

STING or Sting: cGAS-STING-Mediated Immune Response to Protozoan Parasites

Trends in Parasitology
Yifan Sun, Yang Cheng
July 29, 2020

Advancing Mass Spectrometry Technology in cGMP Environments

Trends in Biotechnology
Da Ren

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