Signal Regulation of Autophagy Initiation

Autophagy is an important process in degradation of proteins and organelles, survival during nutrient starvation and cellular remodelling. It is regulated by a complex network of signaling cascades. Discover the latest research on signal regulation of autophagy initiation here.

September 21, 2021
Open Access

PCV2 targets cGAS to inhibit type I interferon induction to promote other DNA virus infection.

PLoS Pathogens
Zhenyu WangYong Huang
September 20, 2021
Open Access

Myrislignan Induces Redox Imbalance and Activates Autophagy in Toxoplasma gondii.

Frontiers in Cellular and Infection Microbiology
Jili ZhangJiyu Zhang
September 20, 2021

UCHL3 plays an important role in the occurrence and development of melanoma.

Oncology Letters
Runzhi HeFang Cheng
September 18, 2021

Omp31 of Brucella Inhibits NF-κB p65 Signaling Pathway by Inducing Autophagy in BV-2 Microglia.

Neurochemical Research
Zhao WangZhenhai Wang
September 17, 2021
Open Access

GRASP55 restricts early-stage autophagy and regulates spatial organization of the early secretory network.

Biology Open
Jennifer Y LiuJayanta Debnath
September 17, 2021
Open Access

Dynamic modelling of the PI3K/MTOR signalling network uncovers biphasic dependence of mTORC1 activity on the mTORC2 subunit SIN1.

PLoS Computational Biology
Milad GhomlaghiLan K Nguyen
September 11, 2021

Optimization of Beclin 1-Targeting Stapled Peptides by Staple Scanning Leads to Enhanced Antiproliferative Potency in Cancer Cells.

Journal of Medicinal Chemistry
Qifan YangRenxiao Wang
September 10, 2021
Open Access

New Advances in the Research of Resistance to Neoadjuvant Chemotherapy in Breast Cancer.

International Journal of Molecular Sciences
Junsha AnFu Peng
September 10, 2021
Open Access

ATG101 Degradation by HUWE1-Mediated Ubiquitination Impairs Autophagy and Reduces Survival in Cancer Cells.

International Journal of Molecular Sciences
JaeYung LeeHeesun Cheong
September 7, 2021
Open Access

GZ17-6.02 and Pemetrexed Interact to Kill Osimertinib-Resistant NSCLC Cells That Express Mutant ERBB1 Proteins.

Frontiers in Oncology
Laurence BoothPaul Dent

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