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Signal Regulation of Autophagy Initiation

Signal Regulation of Autophagy Initiation diagram by Koukourakis et al, PLOS One
Koukourakis et al, PLOS One

Autophagy is an important process in degradation of proteins and organelles, survival during nutrient starvation and cellular remodelling. It is regulated by a complex network of signaling cascades. Discover the latest research on signal regulation of autophagy initiation here.

Top 20 most recent papers

DNA-dependent protein kinase regulates lysosomal AMP-dependent protein kinase activation and autophagy

AutophagyJanuary 28, 2020
Pietri PuustinenMarja Jäättelä
Nature Communications

Structural basis of p62/SQSTM1 helical filaments and their role in cellular cargo uptake

Nature CommunicationsJanuary 25, 2020
Arjen J JakobiCarsten Sachse
Scientific Reports

Machine learning with autophagy-related proteins for discriminating renal cell carcinoma subtypes

Scientific ReportsJanuary 22, 2020
Zhaoyue HeHans-Uwe Simon
Journal of Cellular Physiology

Ferroptotic agent-induced endoplasmic reticulum stress response plays a pivotal role in the autophagic process outcome

Journal of Cellular PhysiologyJanuary 28, 2020
Young-Sun LeeYong J Lee

Activation of Src-family kinases orchestrate secretion of flaviviruses by targeting mature progeny virions to secretory autophagosomes

bioRxivJanuary 14, 2020
Ming Yuan LiSumana Sanyal
Journal of Cellular Physiology

(Curcumin+sildenafil) enhances the efficacy of 5FU and anti-PD1 therapies in vivo

Journal of Cellular PhysiologyJanuary 28, 2020
Paul DentJohn F Hancock
Viral Immunology

Mechanisms of mTOR and Autophagy in Human Endothelial Cell Infected with Dengue Virus-2

Viral ImmunologyJanuary 25, 2020
Weiying KongLi Zuo
Protein Science : a Publication of the Protein Society

Curvature-sensitive trans-assembly of human Atg8-family proteins in autophagy-related membrane tethering

Protein Science : a Publication of the Protein SocietyJanuary 22, 2020
Saki TaniguchiJoji Mima
Redox Biology

Fundc1-dependent mitophagy is obligatory to ischemic preconditioning-conferred renoprotection in ischemic AKI via suppression of Drp1-mediated mitochondrial fission

Redox BiologyJanuary 7, 2020
Jin WangHao Zhou
Cell Stress & Chaperones

Autophagy and Hsp70 activation alleviate oral epithelial cell death induced by food-derived hypertonicity

Cell Stress & ChaperonesJanuary 25, 2020
Ji YangQian Gao
The American Journal of Clinical Nutrition

The autophagic-lysosomal and ubiquitin proteasome systems are simultaneously activated in the skeletal muscle of gastric cancer patients with cachexia

The American Journal of Clinical NutritionJanuary 23, 2020
Ying ZhangXinying Wang
Oxidative Medicine and Cellular Longevity

Restoration of Autophagic Flux Rescues Oxidative Damage and Mitochondrial Dysfunction to Protect against Intervertebral Disc Degeneration

Oxidative Medicine and Cellular LongevityJanuary 25, 2020
Liang KangYukun Zhang
Annals of the New York Academy of Sciences

Molecular regulation of autophagy machinery by mTOR-dependent and -independent pathways

Annals of the New York Academy of SciencesJanuary 28, 2020
Md Abdul Alim Al-Bari, Pingyong Xu

PAS kinase deficiency reduces aging effects in mice

AgingJanuary 25, 2020
Pilar DongilCarmen Sanz
Frontiers in Physiology

Acute Heat Exposure Alters Autophagy Signaling in C2C12 Myotubes

Frontiers in PhysiologyJanuary 24, 2020
Corey M Summers, Rudy J Valentine
Life Sciences

Circ_0009910 promotes imatinib resistance through ULK1-induced autophagy by sponging miR-34a-5p in chronic myeloid leukemia

Life SciencesJanuary 11, 2020
Hai-Xia CaoZhong-Xing Jiang
Journal of Dairy Science

Increased autophagy mediates the adaptive mechanism of the mammary gland in dairy cows with hyperketonemia

Journal of Dairy ScienceJanuary 14, 2020
Xinwei LiGuowen Liu
Journal of Ethnopharmacology

Mu-Xiang-You-Fang protects PC12 cells against OGD/R-induced autophagy via the AMPK/mTOR signaling pathway

Journal of EthnopharmacologyJanuary 25, 2020
Hui-Xia MaQi-Peng Zhao
Nature Communications

ULK1 phosphorylates Exo70 to suppress breast cancer metastasis

Nature CommunicationsJanuary 9, 2020
Liyuan MaoTianhui Hu

Metabolic effects of RUBCN/Rubicon deficiency in kidney proximal tubular epithelial cells

AutophagyJanuary 17, 2020
Jun MatsudaYoshitaka Isaka

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An autophagosome is the formation of double-membrane vesicles that involve numerous proteins and cytoplasmic components. These double-membrane vesicles are then terminated at the lysosome where they are degraded. Discover the latest research on autophagosomes here.

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