Single Brain Cell Transcriptomes & Methylomes

Single-cell analyses provide a better-resolved picture of complex biological processes and unmask heterogeneity found between cells. Here is the latest research employing single-cell transcriptomics and examining DNA methylomes in brain cells.

June 18, 2021

Targeting the αv integrin-TGF-β axis improves natural killer cell function against glioblastoma stem cells.

The Journal of Clinical Investigation
Hila ShaimKatayoun Rezvani
June 16, 2021
Preprint
Open Access

A CRISPRi/a platform in iPSC-derived microglia uncovers regulators of disease states

BioRxiv : the Preprint Server for Biology
N. M. DraegerMartin Kampmann
June 16, 2021
Preprint
Open Access

Single-cell transcriptome analysis of embryonic and adult endothelial cells allows to rank the hemogenic potential of post-natal endothelium

BioRxiv : the Preprint Server for Biology
A. AdamovChristophe Lancrin
June 15, 2021
Open Access

Cell type hierarchy reconstruction via reconciliation of multi-resolution cluster tree.

Nucleic Acids Research
Minshi PengKathryn Roeder
June 15, 2021

DIAPH1 Variants in Non-East Asian Patients With Sporadic Moyamoya Disease.

JAMA Neurology
Adam J KundishoraKristopher T Kahle
June 15, 2021
Open Access

Expression of Urea Transporter B in Normal and Injured Brain.

Frontiers in Neuroanatomy
Boyue HuangJianhua Ran
June 14, 2021
Review
Open Access

Progress towards a cellularly resolved mouse mesoconnectome is empowered by data fusion and new neuroanatomy techniques.

Neuroscience and Biobehavioral Reviews
Nestor Timonidis, Paul H E Tiesinga
June 12, 2021
Open Access

Likelihood-based tests for detecting circadian rhythmicity and differential circadian patterns in transcriptomic applications.

Briefings in Bioinformatics
Haocheng DingZhiguang Huo
June 12, 2021

Single-cell transcriptome profiling of thyroid hormone effectors in the human fetal neocortex: expression of SLCO1C1, DIO2, and THRB in specific cell types.

Thyroid : Official Journal of the American Thyroid Association
Diego DiezJuan Bernal
June 10, 2021
Preprint
Open Access

Emerging single cell endothelial heterogeneity supports sprouting tumour angiogenesis and growth

BioRxiv : the Preprint Server for Biology
Holger GerhardtJ.-C. Marine
June 9, 2021
Open Access

Generation and characterisation of a cell-type specific, inducible Cre-driver line to study olfactory processing.

The Journal of Neuroscience : the Official Journal of the Society for Neuroscience
Anzhelika KoldaevaIzumi Fukunaga
June 8, 2021

Age-Dependent Transcriptional Alterations in Cardiac Endothelial Cells.

Physiological Genomics
Uchenna EmechebeAnthony Paul Barnes
June 7, 2021

Cell-type diversity in the bed nucleus of the stria terminalis to regulate motivated behaviors.

Behavioural Brain Research
Maria M Ortiz-JuzaJose Rodriguez-Romaguera
June 6, 2021
Preprint
Open Access

HyDrop: droplet-based scATAC-seq and scRNA-seq using dissolvable hydrogel beads

BioRxiv : the Preprint Server for Biology
F. V. De RopStein Aerts
June 6, 2021

Single cell RNA sequencing detects persistent cell type- and methylmercury exposure paradigm-specific effects in a human cortical neurodevelopmental model.

Food and Chemical Toxicology : an International Journal Published for the British Industrial Biological Research Association
M Diana NeelyAaron B Bowman

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