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Single-Cell Atlas of the Adult Human Heart.

Single-Cell Atlas of the Adult Human Heart. diagram by undefined

Examining the genomics, transcriptomics, proteomics and metabolomics of the human heart at the single cell level will help build a single cell atlas of heart, which would give a unique ID card for each cell type, a three-dimensional map of how cell types work together to form tissues and insights into how changes in the map underlie health and disease of the heart. Disocver the latest research on the single cell atlas of the human heart here.

Top 20 most recent papers

Secondary motifs enable concentration-dependent regulation by Rbfox family proteins

bioRxivNovember 12, 2019
Bridget E. BeggChristopher B. Burge
BMC Cancer

Clonal relationship of synchronous head and neck cancer and esophageal cancer assessed by single nucleotide polymorphism-based loss of heterozygosity analysis

BMC CancerDecember 3, 2019
Somkiat SunpaweravongNatini Jinawath

A TBX5 dosage-sensitive gene regulatory network for human congenital heart disease

bioRxivNovember 8, 2019
Benoit G. BruneauHolger Heyn
Circulation Research

Integrative Omics Approach to Identifying Genes Associated with Atrial Fibrillation

Circulation ResearchDecember 5, 2019
Biqi WangHonghuang Lin

A Novel Role of Cyclic Nucleotide Phosphodiesterase 10A in Pathological Cardiac Remodeling and Dysfunction

CirculationDecember 5, 2019
S I ChenChen Hong Yan

High-resolution transcriptomic profiling of the heart during chronic stress reveals cellular drivers of cardiac fibrosis and hypertrophy

bioRxivNovember 25, 2019
Micheal A. McLellanAlexander R. Pinto
JAMA Cardiology

Association Between Change in Circulating Progenitor Cells During Exercise Stress and Risk of Adverse Cardiovascular Events in Patients With Coronary Artery Disease

JAMA CardiologyDecember 4, 2019
Kasra MoazzamiArshed A Quyyumi

Asymmetric Hapln1a drives regionalised cardiac ECM expansion and promotes heart morphogenesis during zebrafish development

bioRxivNovember 11, 2019
Christopher J DerrickEmily S Noël

Tfam knockdown results in reduction of mtDNA copy number, OXPHOS deficiency and abnormalities in zebrafish embryos

bioRxivNovember 14, 2019
Auke B C OttenBert Smeets
Clinical Cancer Research : an Official Journal of the American Association for Cancer Research

Pre-operative β-blockade with propranolol reduces biomarkers of metastasis in breast cancer: a Phase II randomized trial

Clinical Cancer Research : an Official Journal of the American Association for Cancer ResearchNovember 21, 2019
Jonathan G HillerErica K Sloan
Physiological Reviews

mRNA Metabolism in Cardiac Development and Disease - Life After Transcription

Physiological ReviewsNovember 21, 2019
Chen Gao, Yi-bin Wang
Stem Cell Research & Therapy

Immunomodulatory effects of interferon-γ on human fetal cardiac mesenchymal stromal cells

Stem Cell Research & TherapyDecember 4, 2019
Karl-Henrik GrinnemoCecilia Osterholm
JCI Insight

Transcriptional heterogeneity of fibroblasts is a hallmark of the aging heart

JCI InsightNovember 14, 2019
Ramon VidalSascha Sauer
Scientific Reports

Genomewide Gene-by-Sex Interaction Scans Identify ADGRV1 for Sex Differences in Opioid Dependent African Americans

Scientific ReportsDecember 2, 2019
Bao-Zhu YangJoel E. Gelernter
Circulation. Genomic and Precision Medicine

An Integrated Multi-Omics Approach to Identify Genetic Underpinnings of Heart Failure and its Echocardiographic Precursors: The Framingham Heart Study

Circulation. Genomic and Precision MedicineNovember 8, 2019
Charlotte Brix AnderssonRamachandran S. Vasan
BMJ Open

Shanghai Preconception Cohort (SPCC) for the association of periconceptional parental key nutritional factors with health outcomes of children with congenital heart disease: a cohort profile

BMJ OpenNovember 24, 2019
Dingmei WangSPCC group
The Journal of Pediatrics

Risk Factors for Red Blood Cell Transfusions in Children Undergoing Cardiac Catheterization

The Journal of PediatricsNovember 12, 2019
Ronald A LigonChristopher J Petit
Circulation. Genomic and Precision Medicine

Peripheral Blood RNA Levels of QSOX1 and PLBD1 are New Independent Predictors of Left Ventricular Dysfunction after Acute Myocardial Infarction

Circulation. Genomic and Precision MedicineNovember 22, 2019
Maarten VanhaverbekePeter R Sinnaeve

Combinatorial chromatin dynamics foster accurate cardiopharyngeal fate choices

ELifeNovember 20, 2019
Claudia RacioppiLionel A Christiaen
Anesthesia and Analgesia

Distribution of Extreme Vital Signs and Complete Blood Count Values of Healthy Parturients: A Retrospective Database Analysis and Review of the Literature

Anesthesia and AnalgesiaNovember 20, 2019
Roi GatSharon Einav

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