Single-Cell Atlas of the Heart

Combining genomic, transcriptomic, proteomic, and metabolomic data from the human heart at the single cell level will result in a single cell atlas of heart. This three-dimensional map of how cell types work together to form tissues will provide insights into how cellular functioning underlies health and disease of the heart. Disocver the latest research on the single cell atlas of the human heart here.

January 16, 2022

Shortening the thick filament by partial deletion of titin's C-zone alters cardiac function by reducing the operating sarcomere length range.

Journal of Molecular and Cellular Cardiology
Mei MethawasinHenk Granzier
January 15, 2022
Review

Role of Cardiac Fibroblasts in Cardiac Injury and Repair.

Current Cardiology Reports
Maoying Han, Bin Zhou
January 14, 2022
Open Access

Nuclei Detection for 3D Microscopy With a Fully Convolutional Regression Network.

IEEE Access : Practical Innovations, Open Solutions
Maryse Lapierre-LandryMichael W Jenkins
January 13, 2022

MicroRNA-365 regulates human cardiac action potential duration.

Nature Communications
Dena EsfandyariStefan Engelhardt
January 12, 2022
Preprint
Open Access

Differential Requirement of DICER1 Activity during Development of Mitral and Tricuspid Valves

BioRxiv : the Preprint Server for Biology
S. YanKai Jiao
January 11, 2022
Open Access

Single-Cell Analysis Identify Transcription Factor BACH1 as a Master Regulator Gene in Vascular Cells During Aging.

Frontiers in Cell and Developmental Biology
Fei GeDan Meng
January 6, 2022
Preprint
Open Access

Analysis of commonly expressed genes between first trimester fetal heart and placenta cell types in the context of congenital heart disease

BioRxiv : the Preprint Server for Biology
Rebecca WilsonH. Jones
January 6, 2022

CXCL4 drives fibrosis by promoting several key cellular and molecular processes.

Cell Reports
Alsya J AffandiWioleta Marut
January 4, 2022
Review
Open Access

Recent Progress in Cardiovascular Research Involving Single-Cell Omics Approaches.

Frontiers in Cardiovascular Medicine
Zhehao Dai, Seitaro Nomura
January 4, 2022
Open Access

Midkine Prevents Calcification of Aortic Valve Interstitial Cells via Intercellular Crosstalk.

Frontiers in Cell and Developmental Biology
Qian ZhouXimiao He
January 4, 2022
Open Access

Single-Cell Analysis of Target Antigens of CAR-T Reveals a Potential Landscape of "On-Target, Off-Tumor Toxicity".

Frontiers in Immunology
Yinyin ZhangRongqun Guo
December 29, 2021
Preprint
Open Access

A single cell transcriptional roadmap for human pacemaker cell differentiation

BioRxiv : the Preprint Server for Biology
A. WiesingerHarsha D. Devalla
December 28, 2021

Polar Gini Curve: A Technique to Discover Gene Expression Spatial Patterns from Single-cell RNA-seq Data.

Genomics, Proteomics & Bioinformatics
Thanh Minh NguyenJake Y Chen
December 25, 2021

Three-dimensional transistor arrays for intra- and inter-cellular recording.

Nature Nanotechnology
Yue GuSheng Xu

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