Feed Preview
Single-Cell Atlas of the Adult Human Heart.
Jose Luis Calvo, ShutterstockExamining the genomics, transcriptomics, proteomics and metabolomics of the human heart at the single cell level will help build a single cell atlas of heart, which would give a unique ID card for each cell type, a three-dimensional map of how cell types work together to form tissues and insights into how changes in the map underlie health and disease of the heart. Disocver the latest research on the single cell atlas of the human heart here.
Top 20 most recent papers
Dynamic Transcriptional Responses to Injury of Regenerative and Non-regenerative Cardiomyocytes Revealed by Single-Nucleus RNA Sequencing
Developmental CellMarch 30, 2020
Miao CuiEric N Olson
White Blood Cells and Blood Pressure: A Mendelian Randomization Study
CirculationMarch 10, 2020
Mateusz SiedlinskiTomasz J Guzik
5
Selective inhibition of TGFβ1 activation overcomes primary resistance to checkpoint blockade therapy by altering tumor immune landscape
Science Translational MedicineMarch 28, 2020
Constance J MartinThomas Schürpf
24
13
MYH7B variants cause hypertrophic cardiomyopathy by activating the CaMK-signaling pathway
Science China. Life SciencesMarch 25, 2020
Peng ChenDao-Wen Wang
1
The ACE2 expression in human heart indicates new potential mechanism of heart injury among patients infected with SARS-CoV-2
Cardiovascular ResearchApril 1, 2020
Liang ChenChenglong Xiong
Short-term exposure to intermittent hypoxia in mice leads to changes in gene expression seen in chronic pulmonary disease
bioRxivMarch 8, 2020
Gang WuDavid F. Smith
17
A metabolic shift to glycolysis promotes zebrafish tail regeneration through TGF-β dependent dedifferentiation of notochord cells to form the blastema
bioRxivMarch 4, 2020
Jason W. SinclairShawn M Burgess
42
Metabolic Immunomodulation, Transcriptional Regulation, and Signal Protein Expression Define the Metabotype and Effector Functions of Five Polarized Macrophage Phenotypes
bioRxivMarch 11, 2020
Catherine B AndersMary Cloud B Ammons
4
Comparative transcriptomic analysis of rhizomes, stems, and leaves of Polygonatum odoratum (Mill.) Druce reveals candidate genes associated with polysaccharide synthesis
GeneApril 1, 2020
Shengxiang ZhangDaiyin Peng
Air Exposure Affects Physiological Responses, Innate Immunity, Apoptosis and DNA Methylation of Kuruma Shrimp, Marsupenaeus japonicus
Frontiers in PhysiologyApril 1, 2020
Panpan WangYong Mao
Extensive Changes in Transcriptomic "Fingerprints" and Immunological Cells in the Large Organs of Patients Dying of Acute Septic Shock and Multiple Organ Failure Caused by Neisseria meningitidis
Frontiers in Cellular and Infection MicrobiologyMarch 11, 2020
Berit Sletbakk BruslettoReidun Øvstebø
Parental exposure to bisphenol A affects pharyngeal cartilage development and causes global transcriptomic changes in zebrafish (Danio rerio) offspring
ChemosphereMarch 26, 2020
Wenlong HuangKusheng Wu
1
(E)-N'-(1-(7-Hydroxy-2-Oxo-2H-Chromen-3-Yl) Ethylidene) Benzohydrazide, a Novel Synthesized Coumarin, Ameliorates Isoproterenol-Induced Myocardial Infarction in Rats through Attenuating Oxidative Stress, Inflammation, and Apoptosis
Oxidative Medicine and Cellular LongevityMarch 28, 2020
Anouar FerianiKais Mnafgui
Single-cell RNA-seq data analysis on the receptor ACE2 expression reveals the potential risk of different human organs vulnerable to 2019-nCoV infection
Frontiers of MedicineMarch 15, 2020
Xin ZouZeguang Han
27
1
Assessing the heterogeneity of cardiac non-myocytes and the effect of cell culture with integrative single cell analysis
bioRxivMarch 5, 2020
Brian IskraGregory J. Aune
5
Post-Transcriptional Dysregulation of microRNA and Alternative Polyadenylation in Colorectal Cancer
Frontiers in GeneticsMarch 11, 2020
Zhanrui MaoYani Kang
Cold-Inducible RNA-Binding Protein Prevents an Excessive Heart Rate Response to Stress by Targeting Phosphodiesterase
Circulation ResearchMarch 28, 2020
Duanyang XieYi-Han Chen
Insulin receptor substrates differentially exacerbate insulin-mediated left ventricular remodeling
JCI InsightMarch 28, 2020
Christian RiehleE Dale Abel
12
Tet2-mediated clonal hematopoiesis in non-conditioned mice accelerates age-associated cardiac dysfunction
JCI InsightMarch 11, 2020
Ying WangKenneth Walsh
4
Error-corrected sequencing strategies enable comprehensive detection of leukemic mutations relevant for diagnosis and minimal residual disease monitoring
BMC Medical GenomicsMarch 6, 2020
Erin L CrowgeyTodd E Druley
9
2