Single Cell Chromatin Profiling

The novel CUT&Tag technique has the potential to allow single cell profiling of chromatin accessibility, histones, and TFs. This will provide novel insight into cellular heterogeneity and cell states. Discover the latest research on single cell chromatin profiling here.

August 14, 2020
Preprint
Open Access

simATAC: A Single-cell ATAC-seq Simulation Framework

BioRxiv : the Preprint Server for Biology
Z. Navidi GhazianiBo Wang
August 17, 2020
Preprint
Open Access

Parkinsons Disease Genetic Risk Evaluation in Microglia Highlights Autophagy and Lysosomal Genes

BioRxiv : the Preprint Server for Biology
Alix BoomsG. A. Coetzee
September 8, 2020
Open Access

COCOA: coordinate covariation analysis of epigenetic heterogeneity

Genome Biology
John T LawsonNathan C Sheffield
July 31, 2020
Open Access

The changing mouse embryo transcriptome at whole tissue and single-cell resolution

Nature
Peng HeBarbara J Wold
September 16, 2020
Review
Open Access

Single-cell sequencing techniques from individual to multiomics analyses

Experimental & Molecular Medicine
Yukie KashimaAyako Suzuki
August 22, 2020

Unified Analysis of Multiple ChIP-Seq Datasets

Methods in Molecular Biology
Gang MaAndrew P Hutchins
August 19, 2020

Chromatin integration labeling for mapping DNA-binding proteins and modifications with low input

Nature Protocols
Tetsuya HandaHiroshi Kimura
September 3, 2020
Preprint
Open Access

Unique contribution of enhancer-driven and master-regulator genes to autoimmune disease revealed using functionally informed SNP-to-gene linking strategies

BioRxiv : the Preprint Server for Biology
Kushal K DeyA. Price
August 21, 2020

Visualization of Chromatin Dynamics by Live Cell Microscopy Using CRISPR/Cas9 Gene Editing and ANCHOR Labeling

Methods in Molecular Biology
Ezio T FokMusa M Mhlanga
August 28, 2020
Open Access

Cytoplasmic Citrate Flux Modulates the Immune Stimulatory NKG2D Ligand MICA in Cancer Cells

Frontiers in Immunology
Sofie H MøllerSøren Skov
August 28, 2020
Open Access

regSNPs-ASB: A Computational Framework for Identifying Allele-Specific Transcription Factor Binding From ATAC-seq Data

Frontiers in Bioengineering and Biotechnology
Siwen XuYunlong Liu
August 7, 2020

Distinct Regulatory Programs Control the Latent Regenerative Potential of Dermal Fibroblasts during Wound Healing

Cell Stem Cell
Sepideh AbbasiJeff Biernaskie
September 15, 2020

Nuclei Isolation from Fresh Frozen Brain Tumors for Single-Nucleus RNA-seq and ATAC-seq

Journal of Visualized Experiments : JoVE
Ashwin NarayananSevin Turcan
September 18, 2020

Multi-omic comparison of Alzheimer's variants in human ESC-derived microglia reveals convergence at APOE

The Journal of Experimental Medicine
Tongfei LiuHuaxi Xu
August 28, 2020
Open Access

ATAC-seq footprinting unravels kinetics of transcription factor binding during zygotic genome activation

Nature Communications
Mette BentsenMario Looso
August 6, 2020
Open Access

Chromatin accessibility landscape of pediatric T-lymphoblastic leukemia and human T-cell precursors

EMBO Molecular Medicine
Büşra Erarslan-UysalAndreas E Kulozik
August 14, 2020

Massively parallel single-cell mitochondrial DNA genotyping and chromatin profiling

Nature Biotechnology
Caleb A LareauVijay G Sankaran
August 14, 2020
Preprint
Open Access

A comparative analysis of chromatin accessibility in cattle, pig, and mouse tissues

BioRxiv : the Preprint Server for Biology
M. M. HalsteadPABLO J ROSS
September 8, 2020
Preprint
Open Access

Scalable, multimodal profiling of chromatin accessibility and protein levels in single cells

BioRxiv : the Preprint Server for Biology
E. P. MimitouPeter Smibert

Sign up to follow this feed and discover related papers.

Related Feeds

Adult Kidney Organoids at Single Cell Resolution

Single-cell RNA sequencing of the adult human kidney transcriptome can provide molecular information about cell-specific responses to environmental variables and disease states. This information can provide a dataset to benchmark human kidney organoids. Discover the latest research on adult kidney organoids at single cell resolution here.

Bioconductor Software Package: Human Cell Atlas

The open source software R / Bioconductor is used for statistical analysis and visualization, with continual generation of new analysis packages and updates. Find the latest research on Programming: Bioconductor Software Packages here.

Cell Atlas of the Human Eye

Constructing a cell atlas of the human eye will require transcriptomic and histologic analysis over the lifespan. This understanding will aid in the study of development and disease. Find the latest research pertaining to the Cell Atlas of the Human Eye here.

Cell Atlas of the human Thymus: Development & Aging

Examining the genomics, transcriptomics, proteomics, and metabolomics of the human thymus gland at the single cell level will help build a single cell atlas of this gland, which would give a unique ID card for each cell type, a three-dimensional map of how cell types work together to form tissues, and insights into how changes in the map underlie health and disease of the thymus gland during development and aging. Discover the latest research on the cell atlas of the human thymus here.

Deep Visual Proteomics: Image-Guided Cell Characterization

Investigating human cellular proteins through a combination of highly multiplexed imaging and proteomic analyses can help characterize all human cells at the proteomic level. Discover the latest research on deep visual proteomics here.

Human Adipose Tissue Communication

Adipose tissue is composed of different cell types including adipocytes and stromal cells. The complex intercellular communication is crucial for growth and survival. Characterization of the transcriptome of adipose tissue will help understand this complex network and the development of disease. Discover the latest research on human adipose tissue communication here.

Human Adipose Tissue Heterogeneity

Examining the genomics, transcriptomics, proteomics, and metabolomics of the human adipose tissues at the single cell level will help build a single cell atlas of these tissues, which would give a unique ID card for each cell type, a three-dimensional map of how cell types work together to form tissues, and insights into how changes in the map underlie health and disease states in which adipose tissues are involved. Disocver the latest research on the human adipose tissue heterogeneity here.

Human Brain Cell: Single Cell Transcriptomes & DNA Methylomes

Single-cell analyses provide a better-resolved picture of complex biological processes and unmask heterogeneity found between cells. Here is the latest research employing single-cell transcriptomics and examining DNA methylomes in brain cells.

Human Cell Atlas Along the Gut-Brain Axis

Examining the genomics, transcriptomics, proteomics, and metabolomics of the gut-brain axis at the single cell level will help build a single cell atlas of this axis, which would give a unique ID card for each cell type, a three-dimensional map of how cell types work together to form tissues, and insights into how changes in the map underlie health and disease of the GI system. Disocver the latest research on the human cell atlas of the gut-brain axis here.

Human Cell Atlas of the Female Reproductive System

Examining genomics, transcriptomics, proteomics and metabolomics of the female reproductive system at the single cell level will help build a three-dimensional cellular map and insights into the health and disease of the female reproductive system. Discover the latest research on the human cell atlas of the female reproductive system here.

© 2020 Meta ULC. All rights reserved
/feed-previews/single-cell-chromatin-profiling/6f6bd076-c119-4d14-a2c5-0f609d9399ea