Feed Preview

Single-Cell Neurogenetics

Single-Cell Neurogenetics diagram by Serj.hop, Wikimedia
Serj.hop, Wikimedia

Single-cell analysis, including single-cell RNA sequencing, allows the discovery of new cell populations and expresssion patterns at single-cell resolution. When applied to neurogenetics, single-cell analysis can potentially uncover novel biological mechanisms underlying neurological disorders. Here is the latest research on Single-Cell Neurogenetics.

Top 20 most recent papers
Practical Neurology

Relapsing necrotising encephalomyelopathy due to RANBP2 mutation

Practical NeurologyFebruary 24, 2019
Erin KellyMark Slee
3
2
bioRxiv

Genes influenced by MEF2C contribute to neurodevelopmental disease via gene expression changes that affect multiple types of cortical excitatory neurons

bioRxivDecember 16, 2019
Donna CosgroveDerek W. Morris
6
bioRxiv

Genome-wide Association Study of Alcohol Consumption and Use Disorder in Multiple Populations (N = 274,424)

bioRxivJanuary 25, 2019
Henry KranzlerJoel Gelernter
40
5
Frontiers in Genetics

Identifying Common Genes, Cell Types and Brain Regions Between Diseases of the Nervous System

Frontiers in GeneticsDecember 19, 2019
Mengling QiHuiying Zhao
3
Nature Communications

Integrated single cell analysis of blood and cerebrospinal fluid leukocytes in multiple sclerosis

Nature CommunicationsJanuary 16, 2020
David SchafflickGerd Meyer Zu Horste
2
Molecular Autism

Impact of on-site clinical genetics consultations on diagnostic rate in children and young adults with autism spectrum disorder

Molecular AutismAugust 14, 2019
Arnold MunnichMoise Assouline
3
13
Médecine sciences : M/S

Twenty years of on-site clinical genetics consultations for people with ASD

Médecine sciences : M/SDecember 18, 2019
Arnold MunnichMoise Assouline
4
bioRxiv

Brainstem organoids from human pluripotent stem cells contain neural crest population

bioRxivNovember 4, 2019
Nobuyuki EuraEiichiro Mori
8
2
ELife

Molecular and anatomical organization of the dorsal raphe nucleus

ELifeAugust 15, 2019
Kee Wui HuangBernardo L Sabatini
52
1
41
bioRxiv

Leveraging Gene Co-expression Patterns to Infer Trait-Relevant Tissues in Genome-wide Association Studies

bioRxivJuly 17, 2019
Lulu ShangXiang Zhou
16
5
bioRxiv

Validation of new bioinformatic tools to identify expanded repeats: a non-reference intronic pentamer expansion in RFC1 causes CANVAS

bioRxivApril 4, 2019
Haloom RafehiPaul J Lockhart
15
17
bioRxiv

Unraveling ChR2-driven stochastic Ca2+ dynamics in astrocytes – A call for new interventional paradigms

bioRxivFebruary 13, 2019
Arash MoshkforoushJorge Riera
9
2
Cell Death & Disease

Direct neuronal reprogramming of olfactory ensheathing cells for CNS repair

Cell Death & DiseaseSeptember 11, 2019
Xiu SunZhida Su
2
1
8
Developmental Medicine and Child Neurology

The expanding spectrum of movement disorders in genetic epilepsies

Developmental Medicine and Child NeurologyDecember 1, 2019
Apostolos PapandreouManju A Kurian
10
American Journal of Human Genetics

Bioinformatics-Based Identification of Expanded Repeats: A Non-reference Intronic Pentamer Expansion in RFC1 Causes CANVAS

American Journal of Human GeneticsJune 25, 2019
Haloom RafehiPaul J Lockhart
17
38
1
bioRxiv

Neuron subtype-specific effector gene expression in the Motor Ganglion of Ciona

bioRxivMay 17, 2019
Susanne GibboneyAlberto Stolfi
9
bioRxiv

Integrative genomics approach identifies conserved transcriptomic networks in Alzheimer's disease

bioRxivJuly 7, 2019
Samuel MorabitoVivek Swarup
17
10
Frontiers in Genetics

Comprehensive Genetic Analysis of a Hungarian Amyotrophic Lateral Sclerosis Cohort

Frontiers in GeneticsSeptember 3, 2019
Kornélia TripolszkiMárta Széll
2
1
9
IEEE Transactions on Medical Imaging

Joint-connectivity-based sparse canonical correlation analysis of imaging genetics for detecting biomarkers of Parkinson's disease

IEEE Transactions on Medical ImagingMay 31, 2019
Mansu KimHyunjin Park
2
1
5
Current Pharmaceutical Design

Neurological disorder drug discovery from gene expression with tensor decomposition

Current Pharmaceutical DesignDecember 11, 2019
Y-H Taguchi, Turki Turki
3

See more papers from this feed

Related Feeds

ALS: Genetics

Amyotrophic lateral sclerosis (ALS) is a progressive neurodegenerative disorder characterized by muscle weakness. ALS is a genetically heterogeneous disorder with several causative genes. Here are the latest discoveries pertaining to the genetics of this disease.

Cognitive Decline: Environmental And Genetic Factors

This feed focuses on the role of environmental and genetic factors including environmental policies, disease susceptibility, and socioeconomic status on cognitive decline. Here is the latest research.

Epigenetic Changes in Pain

Targeted epigenetic interventions provide the tools to prevent nociceptive sensitization, mood-related symptoms, and other adaptations that occur in response to injury or inflammation, which will facilitate pain management and improve treatment efficacy in many chronic pain conditions. Here is the latest research on the epigenetics changes in pain.

Epigenetic Regulation of Microglia Functions

Microglial cells are instrumental in the maintenance of homeostasis in the CNS and can contribute to neurodegenerative disorders. Epigenetic mechanisms and transcriptional regulation may be potential therapeutic targets for their activation or suppression. Discover the latest research on epigenetic regulation of microglial functions here.

Gene-Environment Interaction & Behaviour

Gene-environment interaction is when two different genotypes respond to environmental variation in different ways.Genes and environment interact to form an individual's personality. Abnormal or extreme behaviour could thus be explained by hereditary factors in combination with poor environmental conditions.

Genetic Influences on Brain Development

The genetic landscape of an individual can have drastic effects on brain development and brain developmental disorders. Discover the latest research here.

Genetic Networks Underlying Habituation

Habituation, the gradual waning of an evoked behavioral response with repeated stimulation, is a basic and universal form of learning. This feed explores the genetic networks that are involved in the occurence of habituation.

Genetic Screens in iPSC-Derived Brain Cells

Genetic screening is a critical tool that can be employed to define and understand gene function and interaction. This feed focuses on genetic screens conducted using induced pluripotent stem cell (iPSC)-derived brain cells.

Genetics of Pain

Subtle changes in DNA could partly explain the variation in individual differences in pain. There is growing evidence that a number of genes play a critical role in determining pain sensitivity, pain reporting and susceptibility to developing chronic pain and their response to surgical outcomes primarily, pain.

Immunogenetics of CNS Tumors

Central nervous system (CNS) tumors have a unique tumor immune microenvironment, where immune cells can play a role in disease progression and resistance to therapy. Studying the immunogenetics of these cells can uncover mechanisms underlying their role in CNS tumors. Here is the latest research.

© 2020 Meta ULC. All rights reserved
/feed-previews/single-cell-neurogenetics/b67f67da-c9b3-4227-a8be-dca08d308e39