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Single-Cell Neurogenetics

Single-Cell Neurogenetics diagram by Serj.hop

Single-cell analysis, including single-cell RNA sequencing, allows the discovery of new cell populations and expresssion patterns at single-cell resolution. When applied to neurogenetics, single-cell analysis can potentially uncover novel biological mechanisms underlying neurological disorders. Here is the latest research on Single-Cell Neurogenetics.

Top 20 most recent papers

Integrative functional genomic analysis of human brain development and neuropsychiatric risks

ScienceDecember 14, 2018
Ming-Feng LiNenad Sestan

The microbiota regulate neuronal function and fear extinction learning

NatureOctober 1, 2019
Coco ChuDavid Artis

Spatiotemporal transcriptomic divergence across human and macaque brain development

ScienceDecember 14, 2018
Ying ZhuNenad Sestan

Genetics and Pathway Analysis of Normative Cognitive Variation in the Philadelphia Neurodevelopmental Cohort

bioRxivSeptember 2, 2019
Shraddha PaiGary D. Bader

Genome-wide Association Study of Alcohol Consumption and Use Disorder in Multiple Populations (N = 274,424)

bioRxivJanuary 25, 2019
Henry R. KranzlerJoel E. Gelernter
American Journal of Human Genetics

Bioinformatics-Based Identification of Expanded Repeats: A Non-reference Intronic Pentamer Expansion in RFC1 Causes CANVAS

American Journal of Human GeneticsJune 25, 2019
Haloom RafehiPaul J. Lockhart
Molecular Autism

Impact of on-site clinical genetics consultations on diagnostic rate in children and young adults with autism spectrum disorder

Molecular AutismAugust 7, 2019
Arnold MunnichMoïse Assouline

Molecular and anatomical organization of the dorsal raphe nucleus

ELifeAugust 14, 2019
Kee Wui HuangBernardo Luis Sabatini

Incomplete annotation of disease-associated genes is limiting our understanding of Mendelian and complex neurogenetic disorders

bioRxivDecember 19, 2018
David Y. ZhangMina Ryten

Brainstem organoids from human pluripotent stem cells contain neural crest population

bioRxivNovember 4, 2019
Nobuyuki EuraEiichiro Mori
Molecular Psychiatry

Postmortem evidence of brain inflammatory markers in bipolar disorder: a systematic review

Molecular PsychiatryJune 27, 2019
Vijayasree Vayalanellore GiridharanTatiana Barichello
Communications Biology

Automated four-dimensional long term imaging enables single cell tracking within organotypic brain slices to study neurodevelopment and degeneration

Communications BiologyMay 1, 2019
Jeremy W LinsleySteven Finkbeiner

Leveraging Gene Co-expression Patterns to Infer Trait-Relevant Tissues in Genome-wide Association Studies

bioRxivJuly 17, 2019
Lulu ShangXiang Zhou

Genome-wide Association Study of Multisite Chronic Pain in UK Biobank

bioRxivDecember 20, 2018
Keira J.A. JohnstonDaniel Jordan Smith
Marine Drugs

Probing Multi-Target Action of Phlorotannins as New Monoamine Oxidase Inhibitors and Dopaminergic Receptor Modulators with the Potential for Treatment of Neuronal Disorders

Marine DrugsJune 24, 2019
Su Hui SeongJae Sue Choi
Physiological Genomics

Breakdown of multiple sclerosis genetics to identify an integrated disease network and potential variant mechanisms

Physiological GenomicsSeptember 5, 2019
C Joy ShepardJeremy W. Prokop
Progress in Neuro-psychopharmacology & Biological Psychiatry

Association of purinergic receptor P2RX7 gene polymorphisms with depression symptoms

Progress in Neuro-psychopharmacology & Biological PsychiatryJanuary 22, 2019
Andrea VereczkeiZsofia Nemoda

Unraveling ChR2-driven stochastic Ca2+ dynamics in astrocytes – A call for new interventional paradigms

bioRxivFebruary 13, 2019
Arash MoshkforoushJorge J Riera
Molecular Genetics and Genomics : MGG

Olfactomedin domain-containing proteins: evolution, functional divergence, expression patterns and damaging SNPs

Molecular Genetics and Genomics : MGGMarch 28, 2019
Qin LiZhixi Su
Scientific Reports

Need for high-resolution Genetic Analysis in iPSC: Results and Lessons from the ForIPS Consortium

Scientific ReportsNovember 21, 2018
Bernt PoppAndré Reis

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