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Single-Cell Neurogenetics

Single-Cell Neurogenetics diagram by Serj.hop, Wikimedia
Serj.hop, Wikimedia

Single-cell analysis, including single-cell RNA sequencing, allows the discovery of new cell populations and expresssion patterns at single-cell resolution. When applied to neurogenetics, single-cell analysis can potentially uncover novel biological mechanisms underlying neurological disorders. Here is the latest research on Single-Cell Neurogenetics.

Top 20 most recent papers
Practical Neurology

Relapsing necrotising encephalomyelopathy due to RANBP2 mutation

Practical NeurologyFebruary 24, 2019
Erin KellyMark Slee

Genes influenced by MEF2C contribute to neurodevelopmental disease via gene expression changes that affect multiple types of cortical excitatory neurons

bioRxivDecember 16, 2019
Donna CosgroveDerek W. Morris

Genome-wide Association Study of Alcohol Consumption and Use Disorder in Multiple Populations (N = 274,424)

bioRxivJanuary 25, 2019
Henry KranzlerJoel Gelernter
Frontiers in Genetics

Identifying Common Genes, Cell Types and Brain Regions Between Diseases of the Nervous System

Frontiers in GeneticsDecember 19, 2019
Mengling QiHuiying Zhao
Nature Communications

Integrated single cell analysis of blood and cerebrospinal fluid leukocytes in multiple sclerosis

Nature CommunicationsJanuary 16, 2020
David SchafflickGerd Meyer Zu Horste
Molecular Autism

Impact of on-site clinical genetics consultations on diagnostic rate in children and young adults with autism spectrum disorder

Molecular AutismAugust 14, 2019
Arnold MunnichMoise Assouline
Médecine sciences : M/S

Twenty years of on-site clinical genetics consultations for people with ASD

Médecine sciences : M/SDecember 18, 2019
Arnold MunnichMoise Assouline

Brainstem organoids from human pluripotent stem cells contain neural crest population

bioRxivNovember 4, 2019
Nobuyuki EuraEiichiro Mori

Molecular and anatomical organization of the dorsal raphe nucleus

ELifeAugust 15, 2019
Kee Wui HuangBernardo L Sabatini

Leveraging Gene Co-expression Patterns to Infer Trait-Relevant Tissues in Genome-wide Association Studies

bioRxivJuly 17, 2019
Lulu ShangXiang Zhou

Validation of new bioinformatic tools to identify expanded repeats: a non-reference intronic pentamer expansion in RFC1 causes CANVAS

bioRxivApril 4, 2019
Haloom RafehiPaul J Lockhart

Unraveling ChR2-driven stochastic Ca2+ dynamics in astrocytes – A call for new interventional paradigms

bioRxivFebruary 13, 2019
Arash MoshkforoushJorge Riera
Cell Death & Disease

Direct neuronal reprogramming of olfactory ensheathing cells for CNS repair

Cell Death & DiseaseSeptember 11, 2019
Xiu SunZhida Su
Developmental Medicine and Child Neurology

The expanding spectrum of movement disorders in genetic epilepsies

Developmental Medicine and Child NeurologyDecember 1, 2019
Apostolos PapandreouManju A Kurian
American Journal of Human Genetics

Bioinformatics-Based Identification of Expanded Repeats: A Non-reference Intronic Pentamer Expansion in RFC1 Causes CANVAS

American Journal of Human GeneticsJune 25, 2019
Haloom RafehiPaul J Lockhart

Neuron subtype-specific effector gene expression in the Motor Ganglion of Ciona

bioRxivMay 17, 2019
Susanne GibboneyAlberto Stolfi

Integrative genomics approach identifies conserved transcriptomic networks in Alzheimer's disease

bioRxivJuly 7, 2019
Samuel MorabitoVivek Swarup
Frontiers in Genetics

Comprehensive Genetic Analysis of a Hungarian Amyotrophic Lateral Sclerosis Cohort

Frontiers in GeneticsSeptember 3, 2019
Kornélia TripolszkiMárta Széll
IEEE Transactions on Medical Imaging

Joint-connectivity-based sparse canonical correlation analysis of imaging genetics for detecting biomarkers of Parkinson's disease

IEEE Transactions on Medical ImagingMay 31, 2019
Mansu KimHyunjin Park
Current Pharmaceutical Design

Neurological disorder drug discovery from gene expression with tensor decomposition

Current Pharmaceutical DesignDecember 11, 2019
Y-H Taguchi, Turki Turki

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