Single-Cell RNA Sequencing: Brain

Single-cell RNA sequencing is a technique that is used to study an isolated selection of single-cells and obtaining their transcripts which are then used to generate sequence libraries. These can then be used to assess the diversity in the brain and understand neurological diseases. Here is the latest research on single-cell RNA in the brain.

September 16, 2020

What Happened in the Hippocampal Axon in a Rat Model of Posttraumatic Stress Disorder

Cellular and Molecular Neurobiology
Yadi GuanFang Han
September 11, 2020

Single Cell Technologies Define New Therapeutic Avenues for Huntington's Disease

Neuron
Tamara Maiuri, Ray Truant
September 17, 2020
Open Access

Social reprogramming in ants induces longevity-associated glia remodeling

Science Advances
Lihong ShengRoberto Bonasio
September 21, 2020
Preprint
Open Access

Hypothalamic estrogen receptor alpha mediates key side effects of tamoxifen therapy in mice

BioRxiv : the Preprint Server for Biology
Z. ZhangStephanie M Correa
September 22, 2020
Open Access

Genetic mapping of etiologic brain cell types for obesity

ELife
Pascal N TimshelTune H Pers
September 9, 2020
Review
Open Access

Systems-based proteomics to resolve the biology of Alzheimer's disease beyond amyloid and tau

Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology
Sruti RayaproluNicholas T Seyfried
September 14, 2020
Open Access

Telomere length and human hippocampal neurogenesis

Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology
Alish B PalmosTimothy R Powell
September 20, 2020

Transcription factor expression defines subclasses of developing projection neurons highly similar to single-cell RNA-seq subtypes

Proceedings of the National Academy of Sciences of the United States of America
Whitney E HeavnerSusan K McConnell
September 15, 2020

Nuclei Isolation from Fresh Frozen Brain Tumors for Single-Nucleus RNA-seq and ATAC-seq

Journal of Visualized Experiments : JoVE
Ashwin NarayananSevin Turcan
September 22, 2020
Preprint

Multiplex-inhibitor bead mass spectrometry reveals differential kinome signatures in newly diagnosed and recurrent glioblastoma

BioRxiv : the Preprint Server for Biology
A. D. JermakowiczNagi Ayad
September 8, 2020
Preprint
Open Access

Highly enriched hiPSC-derived midbrain dopaminergic neurons robustly models Parkinson's disease.

BioRxiv : the Preprint Server for Biology
G. S. VirdiSonia Gandhi
September 23, 2020

Deconstructing Stepwise Fate Conversion of Human Fibroblasts to Neurons by MicroRNAs

Cell Stem Cell
Kitra CatesAndrew S Yoo
September 23, 2020
Open Access

Trem2 promotes anti-inflammatory responses in microglia and is suppressed under pro-inflammatory conditions

Human Molecular Genetics
Wenfei LiuDervis A Salih
September 4, 2020
Preprint
Open Access

mTOR inhibition in primary neurons and the developing brain represses transcription of cholesterol biosynthesis genes and alters cholesterol levels

BioRxiv : the Preprint Server for Biology
M. SchueleJennifer Winter

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