Single-cell Tumor Analysis

Single-cell technologies are used to help scientists profile gene and protein expression levels in a variety of diseases including cancer. Here is the latest research on single-cell tumor analysis.

January 20, 2021

Single-cell RNA sequencing reveals intratumoral heterogeneity in primary uveal melanomas and identifies HES6 as a driver of the metastatic disease

Cell Death and Differentiation
Charlotte PandianiCorine Bertolotto
January 6, 2021

Single-cell dissection of intratumoral heterogeneity and lineage diversity in metastatic gastric adenocarcinoma

Nature Medicine
Ruiping WangLinghua Wang
January 15, 2021
Open Access

A single-cell based precision medicine approach using glioblastoma patient-specific models

BioRxiv : the Preprint Server for Biology
J. H. ParkAnoop Patel
December 23, 2020

Mesenchymal Niches for Digestive Organ Development, Homeostasis, and Disease

Trends in Cell Biology
Adrian Kwan Ho LoeTae-Hee Kim
January 4, 2021

Characterization of the immune landscape of EGFR-mutant NSCLC identifies CD73/adenosine pathway as a potential therapeutic target

Journal of Thoracic Oncology : Official Publication of the International Association for the Study of Lung Cancer
Xiuning LeJohn V Heymach
December 6, 2020

Applying high-dimensional single-cell technologies to the analysis of cancer immunotherapy

Nature Reviews. Clinical Oncology
Satyen H GohilKenneth J Livak
December 10, 2020
Open Access

Integrative Tumor and Immune Cell Multi-omic Analyses Predict Response to Immune Checkpoint Blockade in Melanoma

Cell Reports Medicine
Valsamo AnagnostouVictor E Velculescu
November 27, 2020
Open Access

Mesenchymal Transformation: The Rosetta Stone of Glioblastoma Pathogenesis and Therapy Resistance

Advanced Science
Zulfikar AzamBakhos A Tannous
December 15, 2020
Open Access

BLADE: Bayesian Log-normAl DEconvolution for enhanced in silico microdissection of bulk gene expression data

Bárbara Andrade BarbosaYongsoo Kim
November 11, 2020
Open Access

Hand2 delineates mesothelium progenitors and is reactivated in mesothelioma

BioRxiv : the Preprint Server for Biology
K. D. PrummelChristian Mosimann
November 14, 2020
Open Access

SCELLECTOR: ranking amplification bias in single cells using shallow sequencing

BMC Bioinformatics
Vivekananda SarangiAlexej Abyzov
December 21, 2020
Open Access

Multi cell line analysis of lysosomal proteomes reveals unique features and novel lysosomal proteins

BioRxiv : the Preprint Server for Biology
F. AkterDominic Winter
November 8, 2020
Open Access

Altered immune response to the annual influenza A vaccine in patients with myeloproliferative neoplasms

British Journal of Haematology
Samah AlimamDonal P McLornan

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