Sirtuins in Metabolic Regulation

Sirtuins, a family of highly conserved NAD+-dependent lysine-specific deacetylases has recently been suggested to have a critical impact in the direction and regulation of many metabolic pathways as well as energy sensing in mammals. Discover the latest research on sirtuins in metabolic regulation here.

August 4, 2020
Open Access

Dioscin Protects against Aβ1-42 Oligomers-Induced Neurotoxicity via the Function of SIRT3 and Autophagy

Chemical & Pharmaceutical Bulletin
Ze ZhangNing Jia
August 12, 2020

Sirtuins as endogenous regulators of lung fibrosis: A current perspective

Life Sciences
Somnath MazumderSamik Bindu
August 6, 2020
Open Access

Berberine Ameliorates Subarachnoid Hemorrhage Injury via Induction of Sirtuin 1 and Inhibiting HMGB1/Nf-κB Pathway

Frontiers in Pharmacology
Xiang-Hua ZhangXiang-Sheng Zhang
August 5, 2020

Role of sirtuin-1 (SIRT1) in hypoxic injury in pancreatic β-cells

Journal of Drug Targeting
Ye-Jee LeeSeung-Hyun Ko
August 9, 2020

Induction of a Timed Metabolic Collapse to Overcome Cancer Chemoresistance

Cell Metabolism
Nick van GastelDavid T Scadden
August 9, 2020

Coronavirus (Covid-19) sepsis: revisiting mitochondrial dysfunction in pathogenesis, aging, inflammation, and mortality

Inflammation Research : Official Journal of the European Histamine Research Society ... [et Al.]
Santosh Shenoy
August 4, 2020
Open Access

SIRT3 is a downstream target of PPAR-α implicated in high glucose-induced cardiomyocyte injury in AC16 cells

Experimental and Therapeutic Medicine
Xiaojuan ZongYueguang Chen
August 11, 2020
Open Access

Exosomes from SIRT1-Overexpressing ADSCs Restore Cardiac Function by Improving Angiogenic Function of EPCs

Molecular Therapy. Nucleic Acids
Hui HuangHairong Wang
August 5, 2020

Flavonoids-mediated SIRT1 signaling activation in hepatic disorders

Life Sciences
Ahmed M SayedAyman M Mahmoud
August 5, 2020
Open Access

Sirtuin 3 mRNA Expression is Downregulated in the Brain Tissues of Alzheimer's Disease Patients: A Bioinformatic and Data Mining Approach

Medical Science Monitor : International Medical Journal of Experimental and Clinical Research
Shuang SongLi Guo
August 3, 2020

Impact of circadian and diurnal rhythms on cellular metabolic function and neurodegenerative diseases

International Review of Neurobiology
S Kendall Smith, Erik S Musiek

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