Spatiotemporal Multi-Organ Developmental Maps

The aim of the Spatiotemporal Multi-Organ Developmental Map Project is to build an atlas of an individual’s organ development program by applying single cell sequencing and 4i spatial maps to primary tissue and matched iPSC-derived organoids. Find the latest research pertaining to these techniques here.

January 20, 2022
Preprint
Open Access

BIN1 regulates electrical activity and network synchronization in hiPSC-derived neurons

BioRxiv : the Preprint Server for Biology
O. SahaMarcos Romualdo Costa
January 16, 2022

SARS-CoV-2 infects the human kidney and drives fibrosis in kidney organoids.

Cell Stem Cell
Jitske JansenRafael Kramann
January 15, 2022

PAX6-positive microglia evolve locally in hiPSC-derived ocular organoids.

Stem Cell Reports
Nobuhiko ShirakiKohji Nishida
January 13, 2022

[Adrenal glands stem cells: general signaling pathways].

Problemy e̊ndokrinologii
O V GlazovaP Y Volchkov
January 13, 2022

Cell trajectory modeling identifies a primitive trophoblast state defined by BCAM enrichment.

Development
Matthew J ShannonAlexander G Beristain
January 12, 2022
Review
Open Access

In Vitro and In Vivo Models to Study Nephropathic Cystinosis.

Cells
Pang Yuk CheungJennifer A Hollywood
January 12, 2022
Open Access

Microglia-like Cells Promote Neuronal Functions in Cerebral Organoids.

Cells
Ilkka FagerlundTarja Malm
January 12, 2022
Open Access

Controllable Fabrication of Composite Core-Shell Capsules at a Macroscale as Organoid Biocarriers.

ACS Applied Bio Materials
Fan HeJianhua Qin
January 12, 2022

Hydrogel Mechanics Influence the Growth and Development of Embedded Brain Organoids.

ACS Applied Bio Materials
Camille Cassel de CampsChristopher Moraes
January 11, 2022

Controlling Morphology and Functions of Cardiac Organoids by Two-Dimensional Geometrical Templates.

Cells, Tissues, Organs
Plansky HoangZhen Ma
January 5, 2022

Intermittent compressive force induces cell cycling and reduces apoptosis in embryoid bodies of mouse induced pluripotent stem cells.

International Journal of Oral Science
Jeeranan ManokawinchokeThanaphum Osathanon
January 4, 2022

The sodium/glucose cotransporters as potential therapeutic targets for CF lung diseases revealed by human lung organoid swelling assay.

Molecular Therapy. Methods & Clinical Development
Hiroyuki HiraiJie Xu
January 1, 2022
Preprint
Open Access

A systematic characterization of intrinsically formed microglia-like cells during retinal organoid differentiation.

BioRxiv : the Preprint Server for Biology
K. BartalskaSandra Siegert
January 1, 2022
Review

Perspectives of future lung toxicology studies using human pluripotent stem cells.

Archives of Toxicology
Atsushi MasuiShimpei Gotoh
December 31, 2021

Mitochondrial phenotypes in iPSC AD models.

Alzheimer's & Dementia : the Journal of the Alzheimer's Association
Kaitlin FlannaganHeather M Wilkins
December 31, 2021
Open Access

Transcriptome Dynamics of Human Neuronal Differentiation From iPSC.

Frontiers in Cell and Developmental Biology
Meltem KuruşGökhan Karakülah
December 31, 2021

Lineage recording in human cerebral organoids.

Nature Methods
Zhisong HeBarbara Treutlein

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