Spliceosome

Spliceosomes are massive RNA protein macromolecules that are cellular machinery involved in the splicing and removal of the non-coding segments of DNA and the ligation of coding segments, exons. Discover the latest research on spliceosomes here.

December 29, 2020

SF3B1 mutant myelodysplastic syndrome: Recent advances

Advances in Biological Regulation
Andrea Pellagatti, Jacqueline Boultwood
January 13, 2021
Open Access

The role of JMJD6/U2AF65/AR-V7 axis in castration-resistant prostate cancer progression

Cancer Cell International
Dali Tong
January 10, 2021

Comprehensive characterisation of intronic mis-splicing mutations in human cancers

Oncogene
Hyunchul JungJung Kyoon Choi
December 29, 2020
Review
Open Access

Clinical Applications of Single-Stranded Oligonucleotides: Current Landscape of Approved and in-Development Therapeutics

Molecular Therapy : the Journal of the American Society of Gene Therapy
Juergen Scharner, Isabel Aznarez
January 7, 2021
Open Access

Targeting alternative splicing by RNAi: from the differential impact on splice variants to triggering artificial pre-mRNA splicing

Nucleic Acids Research
Armin FuchsMaria Kalyna
December 29, 2020
Open Access

PIF4 and HOOKLESS1 Impinge on Common Transcriptome and Isoform Regulation in Thermomorphogenesis

Plant Communications
Huanhuan JinZiqiang Zhu
December 31, 2020

A novel mutation in NEB causing foetal nemaline myopathy with arthrogryposis during early gestation

Neuromuscular Disorders : NMD
Maria L RochaBenjamin Englert
December 29, 2020
Open Access

The spliceosome inhibitors isoginkgetin and pladienolide B induce ATF3-dependent cell death

PloS One
Erin J VanzylBruce C McKay
December 23, 2020

Transcriptome comparison of isotretinoin-effective and isotretinoin-ineffective severe acne vulgaris patients

Journal of Cosmetic Dermatology
Yuchen JiangYue Zheng
January 12, 2021

Adult-type granulosa cell tumor of the ovary: a FOXL2-centric disease

The Journal of Pathology. Clinical Research
Jessica A PilsworthDavid G Huntsman
December 29, 2020
Preprint
Open Access

Expression and Prognostic Significance of m6A-Related Genes in TP53-Mutant Non-Small-Cell Lung Cancer

ResearchSquare
Zhuochen ZhaoLiang Ming
December 29, 2020
Open Access

Decoding the Genetic Alterations in Genes of DNMT Family (DNA Methyl-Transferase) and their Association with Head and Neck Squamous Cell Carcinoma

Asian Pacific Journal of Cancer Prevention : APJCP
Tahreem FathimaJ Vijayashree Priyadharsini
January 9, 2021

U1 snRNP telescripting: molecular mechanisms and beyond

RNA Biology
Yi RanChengguo Yao
December 29, 2020
Case Report
Open Access

A Novel Splice-Site Mutation in the ELN Gene Suggests an Alternative Mechanism for Vascular Elastinopathies

The Application of Clinical Genetics
Camilo Andres Velandia-PiedrahitaRodrigo Cabrera
January 9, 2021
Open Access

Alcohol use disorder causes global changes in splicing in the human brain

Translational Psychiatry
Derek Van BoovenClaes Wahlestedt

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