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Stanford Department of Genetics

Stanford Department of Genetics diagram by Alpha Tauri 3D Graphics, Shutterstock
Alpha Tauri 3D Graphics, Shutterstock

Find the latest research from the Stanford Medicine Department of Genetics here.

Top 20 most recent papers
Science

CRISPR-engineered T cells in patients with refractory cancer

ScienceFebruary 8, 2020
Edward A StadtmauerCarl H June
923
72
10
2
Nature Biotechnology

Fitness effects of CRISPR/Cas9-targeting of long noncoding RNA genes

Nature BiotechnologyFebruary 26, 2020
Max A HorlbeckJonathan S Weissman
12
1
Nature Methods

Long-range single-molecule mapping of chromatin accessibility in eukaryotes

Nature MethodsFebruary 12, 2020
Zohar ShiponyWilliam Greenleaf
261
1
Science

Quantifying mutations in healthy blood

ScienceMarch 29, 2020
Christina Curtis
Journal of Thoracic Oncology : Official Publication of the International Association for the Study of Lung Cancer

New approaches to small cell lung cancer therapy : from the laboratory to the clinic

Journal of Thoracic Oncology : Official Publication of the International Association for the Study of Lung CancerFebruary 5, 2020
John T PoirierTrudy G Oliver
3
3
Nature Methods

3D ATAC-PALM: super-resolution imaging of the accessible genome

Nature MethodsMarch 24, 2020
Liangqi XieZhe Liu
183
1
Nature Biotechnology

Complete, closed bacterial genomes from microbiomes using nanopore sequencing

Nature BiotechnologyFebruary 12, 2020
Eli L MossAmi S Bhatt
410
3
Science Advances

Modified cyclodextrins as broad-spectrum antivirals

Science AdvancesFebruary 18, 2020
Samuel T JonesCaroline Tapparel
85
29
2
Bioinformatics

DeCoDe: degenerate codon design for complete protein-coding DNA libraries

BioinformaticsMarch 17, 2020
Tyler C ShimkoYaron Orenstein
2
bioRxiv

Single-cell transcriptomic analysis of the adult mouse spinal cord

bioRxivMarch 17, 2020
Jacob BlumAaron D. Gitler
36
80
bioRxiv

G-baToN: a versatile cell-cell interaction reporter system.

bioRxivFebruary 2, 2020
Rui TangMonte M Winslow
4

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COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Human Vascular Endothelial Cell Atlas: Young & Old

Examining the genomics, transcriptomics, proteomics and metabolomics of the human vascular endothelial cells at the single cell level will help build a single cell atlas of human vascular endothelium, which would give a unique ID card for each cell type, a three-dimensional map of how cell types work together to form tissues and insights into how changes in the map underlie health and disease of the vascular endothelium from young to old age. Disocver the latest research on the single cell atlas of human vascular endothelial cell atlas here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Telomere Dysfunction

Telomere dysfunction in response to critical telomere shortening induces dna damage checkpoints that lead to cell cycle arrest and/or cell death.

Incretin & Type 1 Diabetes

Incretins are metabolic hormones that stimulate a decrease in glucose levels in the blood and they have been implicated in glycemic regulation in the remission phase of type 1 diabetes. Here is the latest research.

Allen Institute for Brain Science Network (MDS)

The Allen Institute for Brain Science Network is a not-for-profit biomedical research organization that provides open access to multiple neuroscience tools and resources. Find the latest research from tjr Allen Institute for Brain Science Network here.

Severe Acute Respiratory Syndrome

Severe acute respiratory syndrome (SARS) is a viral respiratory disease of zoonotic origin caused by the SARS coronavirus (SARS-CoV). Initial symptoms are flu-like and may include fever, muscle pain, lethargy symptoms, cough, sore throat, and other nonspecific symptoms. SARS may eventually lead to shortness of breath and pneumonia; either direct viral pneumonia or secondary bacterial pneumonia. DIscover the latest research on SARS here.

Computation Neuroscience - Preprints (MDS)

Computation neuroscience employs models, statistics, simulations, and theoretical analyses to understand mechanisms that govern neural functions. Here are the latest preprints in this domain.

LRRK2 & Immunity During Infection (MDS)

Mutations in the LRRK2 gene are a risk-factor for developing Parkinson’s disease. However, LRRK2 has been shown to function as a central regulator of vesicular trafficking, infection, immunity, and inflammation. Here is the latest research on the role of this kinase on immunity during infection.

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