Stem Cell Aging

Aging tissues experience a progressive decline in homeostatic and regenerative capacities, which has been attributed to degenerative changes in tissue-specific stem cells, stem cell niches and systemic cues that regulate stem cell activity. Understanding the molecular pathways involved in this age-dependent deterioration of stem cell function will be critical for developing new therapies for diseases of aging that target the specific causes of age-related functional decline.

January 15, 2022
Open Access

Role of the circadian clock "Death-Loop" in the DNA damage response underpinning cancer treatment resistance

BioRxiv : the Preprint Server for Biology
N. M. VainshelbaumJekaterina Erenpreisa
January 16, 2022

NAP1L2 drives mesenchymal stem cell senescence and suppresses osteogenic differentiation.

Aging Cell
Meilin HuZhiqiang Liu
January 15, 2022

Inhaled corticosteroids reduce senescence in endothelial progenitor cells from patients with COPD.

Koralia PaschalakiPeter J Barnes
January 15, 2022

Decline of regenerative potential of old muscle stem cells: contribution to muscle aging.

The FEBS Journal
Korin SahinyanVahab D Soleimani
January 14, 2022
Open Access

Inflammatory signals from fatty bone marrow supports the early stages of DNMT3a driven clonal hematopoiesis

BioRxiv : the Preprint Server for Biology
N. ZioniLiran Shlush
January 14, 2022

Puerarin action on stem cell proliferation, differentiation and apoptosis: Therapeutic implications for geriatric diseases.

Phytomedicine : International Journal of Phytotherapy and Phytopharmacology
Ruishuang MaYue Li
January 14, 2022

Skin Mirrors Brain: A Chance for Alzheimer's Disease Research.

Advances in Experimental Medicine and Biology
Christos C ZouboulisAmir M Hossini
January 14, 2022

Cellular metabolic basis of altered immunity in the lungs of patients with COVID-19.

Medical Microbiology and Immunology
Shuangyan LiHuaiyong Chen
January 13, 2022

[Adrenal glands stem cells: general signaling pathways].

Problemy e̊ndokrinologii
O V GlazovaP Y Volchkov
January 13, 2022

Reference range of naïve T and T memory lymphocyte subsets in peripheral blood of healthy adult.

Clinical and Experimental Immunology
Ying XiaJianchun Yu
January 12, 2022
Open Access

Exercise reprograms the inflammatory landscape of multiple stem cell compartments during mammalian aging

BioRxiv : the Preprint Server for Biology
L. LiuThomas A Rando
January 12, 2022
Open Access

Metabolic Rewiring by Human Placenta-Derived Mesenchymal Stem Cell Therapy Promotes Rejuvenation in Aged Female Rats.

International Journal of Molecular Sciences
Kyeoung-Hwa Kim, Kyung-Ah Lee

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