Structure-Based Drug Design

Structure-based drug design (sbdd) combines the power of many scientific disciplines, such as x-ray crystallography, nuclear magnetic resonance, medicinal chemistry, molecular modeling, biology, enzymology and biochemistry, in a functional paradigm of drug development. Here is the latest research on sbdd.

August 6, 2020
Review
Open Access

Pharmacological Potential of Small Molecules for Treating Corneal Neovascularization

Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry
Zachary BarryTimothy W Corson
August 6, 2020
Open Access

Plasmapheresis, Anti-ACE2 and Anti-FcγRII Monoclonal Antibodies: A Possible Treatment for Severe Cases of COVID-19

Drug Design, Development and Therapy
Amin Sedokani, Sadegh Feizollahzadeh
August 9, 2020
Open Access

Intelligent Drug Delivery Microparticles with Visual Stimuli-Responsive Structural Color Changes

International Journal of Nanomedicine
Xiaoyan SunBaofen Ye
August 11, 2020

Low temperature bacterial expression of the neutral amino acid transporters SLC1A5 (ASCT2), and SLC6A19 (B0AT1)

Molecular Biology Reports
Michele GalluccioCesare Indiveri
August 12, 2020

Role of Glucose Transporters in Drug Membrane Transport

Current Drug Metabolism
Xin WangZheng Cai
August 6, 2020

Statin therapy improves endothelial dysfunction

Nature Reviews. Drug Discovery
Sarah Crunkhorn
August 11, 2020
Open Access

Fibroblasts Accelerate Formation and Improve Reproducibility of 3D Cellular Structures Printed with Magnetic Assistance

Research : a Science Partner Journal
Sarah MishrikiIshwar K Puri
August 9, 2020

Crystal structures of full length DENV4 NS2B-NS3 reveal the dynamic interaction between NS2B and NS3

Antiviral Research
Wint Wint PhooDahai Luo
August 8, 2020

Identifying and ranking potential cancer drivers using representation learning on attributed network

Methods : a Companion to Methods in Enzymology
Wei PengJianxin Wang
August 6, 2020

Predicting Local Protein 3D Structures Using Clustering Deep Recurrent Neural Network

IEEE/ACM Transactions on Computational Biology and Bioinformatics
Wei Zhong, Feng Gu
August 10, 2020

Integrating DNA-encoded chemical libraries with virtual combinatorial library screening: Optimizing a PARP10 inhibitor

Bioorganic & Medicinal Chemistry Letters
Mike LemkeRaphael M Franzini
August 10, 2020
Open Access

Repurposing approved drugs as potential inhibitors of 3CL-protease of SARS-CoV-2: Virtual screening and structure based drug design

Computational Biology and Chemistry
Franz-Josef Meyer-Almes
August 11, 2020

A semi-supervised learning framework for quantitative structure-activity regression modelling

Bioinformatics
Oliver WatsonJames A Watson
August 6, 2020
Review
Open Access

Marine Terpenoids from Polar Latitudes and Their Potential Applications in Biotechnology

Marine Drugs
Laura Núñez-PonsDaniela Giordano
August 8, 2020
Open Access

Novel TRPV1 Channel Agonists With Faster and More Potent Analgesic Properties Than Capsaicin

Frontiers in Pharmacology
Yorley DuarteFernando González-Nilo

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