Synucleinopathies

Synucleinopathies are neurodegenerative diseases characterized by accumulation of alpha-synuclein protein aggregates in neurons and glial cells. Discover the latest research on synucleinopathies here.

September 15, 2020

Perturbation of in vivo Neural Activity Following α-Synuclein Seeding in the Olfactory Bulb

Journal of Parkinson's Disease
Aishwarya S KulkarniDaniel W Wesson
September 16, 2020
Open Access

Norepinephrine depleting toxin DSP-4 and LPS alter gut microbiota and induce neurotoxicity in α-synuclein mutant mice

Scientific Reports
Sheng SongJau-Shyong Hong
September 15, 2020

Squalamine Restores the Function of the Enteric Nervous System in Mouse Models of Parkinson's Disease

Journal of Parkinson's Disease
Christine L WestWolfgang A Kunze
September 15, 2020
Open Access

Rational design of small molecules able to inhibit α-synuclein amyloid aggregation for the treatment of Parkinson's disease

Journal of Enzyme Inhibition and Medicinal Chemistry
Serena VittorioLaura De Luca
September 18, 2020

Delayed orthostatic hypotension

Autonomic Neuroscience : Basic & Clinical
Christopher H Gibbons, Roy Freeman
September 16, 2020

Changes in the cellular fatty acid profile drive the proteasomal degradation of α-synuclein and enhance neuronal survival

FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology
Mary XylakiEvangelia Emmanouilidou
September 15, 2020

Alpha-Synuclein Aggregates Associated with Mitochondria in Tunnelling Nanotubes

Neurotoxicity Research
Dario ValdinocciDean L Pountney
September 10, 2020

Writing errors in primary progressive aphasia

Applied Neuropsychology. Adult
Maria Rita Lo MonacoMaria Caterina Silveri
September 18, 2020

Gut microbiota dynamics in Parkinsonian mice

ACS Chemical Neuroscience
Emily KlannVinata Vedam-Mai
September 15, 2020

A Comparative Photophysical Study of Structural Modifications of Thioflavin T-Inspired Fluorophores

The Journal of Physical Chemistry Letters
Lisa-Maria NeedhamSteven F Lee
September 12, 2020
Review
Open Access

Fluid Biomarkers for Synaptic Dysfunction and Loss

Biomarker Insights
Elena CamporesiHenrik Zetterberg
September 11, 2020
Open Access

Immunotherapies Targeting α-Synuclein in Parkinson Disease

Federal Practitioner : for the Health Care Professionals of the VA, DoD, and PHS
Fariha Jamal
September 15, 2020

Phosphorylated Alpha-Synuclein Within Cutaneous Autonomic Nerves of Patients With Parkinson's Disease: The Implications of Sample Thickness on Results

The Journal of Histochemistry and Cytochemistry : Official Journal of the Histochemistry Society
Ningshan WangChristopher H Gibbons
September 15, 2020

α-Syn oligomers incubated with Parkinson's disease plasma promote neuron damage

International Journal of Clinical and Experimental Pathology
Weiwei YangNa Yin
September 15, 2020

Neurogranin as a Novel Biomarker in Alzheimer's Disease

Laboratory Medicine
Luisa AgnelloMarcello Ciaccio
September 18, 2020

Association of transient orthostatic hypotension with falls and syncope in patients with Parkinson's disease

Neurology
Fanciulli AlessandraGregor K Wenning

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