Synucleinopathies

Synucleinopathies are neurodegenerative diseases characterized by accumulation of alpha-synuclein protein aggregates in neurons and glial cells. Discover the latest research on synucleinopathies here.

April 14, 2021
Review
Open Access

Synucleinopathy-associated pathogenesis in Parkinson's disease and the potential for brain-derived neurotrophic factor.

NPJ Parkinson's Disease
Kathryn M MillerCaryl E Sortwell
April 12, 2021
Preprint
Open Access

Midbrain organoids with an SNCA gene triplication model key features of synucleinopathy

BioRxiv : the Preprint Server for Biology
N.-V. MohamedThomas M. Durcan
April 12, 2021
Open Access

Fatty Acid-Binding Protein 3 Expression in the Brain and Skin in Human Synucleinopathies.

Frontiers in Aging Neuroscience
Hideki OizumiAtsushi Takeda
April 12, 2021

Granulocyte-macrophage colony-stimulating factor mRNA and Neuroprotective Immunity in Parkinson's disease.

Biomaterials
Katherine E OlsonHoward E Gendelman
April 11, 2021
Preprint
Open Access

Lysosomal Exocytosis Releases Pathogenic α-Synuclein Species from Neurons

BioRxiv : the Preprint Server for Biology
Y. Xue XieManu Sharma
April 11, 2021

In Vivo Diagnosis of Synucleinopathies: A Comparative Study of Skin Biopsy and RT-QuIC.

Neurology
Vincenzo DonadioWenquan Zou
April 8, 2021
Open Access

Validation of α-Synuclein in L1CAM-Immunocaptured Exosomes as a Biomarker for the Stratification of Parkinsonian Syndromes.

Movement Disorders : Official Journal of the Movement Disorder Society
Cheng JiangGeorge K Tofaris
April 9, 2021
Open Access

Mixed pathologies in pancreatic β cells from subjects with neurodegenerative diseases and their interaction with prion protein.

Acta Neuropathologica Communications
Ivan Martinez-ValbuenaMaría-Rosario Luquin
April 8, 2021
Open Access

Comparative Studies in the A30P and A53T α-Synuclein C. elegans Strains to Investigate the Molecular Origins of Parkinson's Disease.

Frontiers in Cell and Developmental Biology
Michele PerniChristopher M Dobson
April 8, 2021
Open Access

Streamlined alpha-synuclein RT-QuIC assay for various biospecimens in Parkinson's disease and dementia with Lewy bodies.

Acta Neuropathologica Communications
Connor BargarShu G Chen
April 6, 2021

Oral subchronic exposure to the mycotoxin ochratoxin A induces key pathological features of Parkinson´s disease in mice six months after the end of the treatment.

Food and Chemical Toxicology : an International Journal Published for the British Industrial Biological Research Association
María IzcoLydia Alvarez-Erviti
April 5, 2021
Open Access

Alpha-synuclein preformed fibrils: a tool to understand Parkinson's disease and develop disease modifying therapy.

Neural Regeneration Research
Piotr Chmielarz, Andrii Domanskyi
April 5, 2021
Open Access

Detection of Dermal Alpha-Synuclein Deposits as a Biomarker for Parkinson's Disease.

Journal of Parkinson's Disease
Kathrin Doppler
April 5, 2021
Review

The gut-brain connection in the pathogenicity of Parkinson disease: Putative role of autophagy.

Neuroscience Letters
Violina KakotyRajeev Taliyan
April 4, 2021
Review
Open Access

Mechanisms of Neurodegeneration in Various Forms of Parkinsonism-Similarities and Differences.

Cells
Dariusz KoziorowskiAndrzej Friedman
April 4, 2021
Review
Open Access

The Latest Research on RT-QuIC Assays-A Literature Review.

Pathogens
Thi-Thu-Trang Dong, Katsuya Satoh

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