T cell Education in the Thymus

T cell education in the thymus is critical for establishing a functional, yet self-tolerant, t cell repertoire. Here is the latest research.

January 15, 2020

Retroviral Gene Transduction into T Cell Progenitors for Analysis of T Cell Development in the Thymus

Methods in Molecular Biology
Ryunosuke MuroTakeshi Nitta
February 20, 2020

Molecular Mechanisms of Notch Signaling in Lymphoid Cell Lineages Development: NF-κB and Beyond

Advances in Experimental Medicine and Biology
G TsaouliM P Felli
April 8, 2020

Distinct Notch1 and BCL11B requirements mediate human γδ/αβ T cell development

EMBO Reports
Anne-Catherine DolensTom Taghon
July 30, 2020
Open Access

Loss of Mef2D function enhances TLR induced IL-10 production in macrophages

Bioscience Reports
Micheal J PattisonJ Simon C Arthur
August 7, 2020
Open Access

Notch2 complements Notch1 to mediate inductive signaling that initiates early T cell development

The Journal of Cell Biology
Maile Romero-WolfHiroyuki Hosokawa
January 15, 2020

Investigating T Cell Receptor Signals In Situ by Two-Photon Microscopy of Thymocytes Expressing Genetic Reporters in Low-Density Chimeras

Methods in Molecular Biology
Marilaine FournierHeather J Melichar
June 27, 2020
Open Access

The P2X7 Receptor as Regulator of T Cell Development and Function

Frontiers in Immunology
Fabio Grassi
July 28, 2020
Open Access

Liver X receptors are required for thymic resilience and T cell output

The Journal of Experimental Medicine
Christopher T ChanFilip K Swirski
March 3, 2020
Open Access

Serafino Zappacosta: An Enlightened Mentor and Educator

Frontiers in Immunology
Ennio CarboneGiuseppe Terrazzano
August 6, 2020
Open Access

Chromatin accessibility landscape of pediatric T-lymphoblastic leukemia and human T-cell precursors

EMBO Molecular Medicine
Büşra Erarslan-UysalAndreas E Kulozik
April 24, 2020

Structure of MHC-Independent TCRs and Their Recognition of Native Antigen CD155

The Journal of Immunology : Official Journal of the American Association of Immunologists
Jinghua LuPeter D Sun
April 25, 2020
Open Access

PRMT5 Is Required for T Cell Survival and Proliferation by Maintaining Cytokine Signaling

Frontiers in Immunology
Yukinori TanakaTaku Kambayashi
February 22, 2020
Open Access

A cell atlas of human thymic development defines T cell repertoire formation

Jong-Eun ParkSarah A Teichmann
December 31, 2019

Idelalisib induces apoptosis in the lymphoid tissues and impairs lung function in mice

Journal of Chemotherapy
Junu A GeorgeAhmed R Alsuwaidi
December 4, 2019
Open Access

ZBTB7B (ThPOK) Is Required for Pathogenesis of Cerebral Malaria and Protection against Pulmonary Tuberculosis

Infection and Immunity
James M KennedyPhilippe Gros

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