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T Cell Reactivity to Tau & Alpha-Synuclein in PD

T Cell Reactivity to Tau & Alpha-Synuclein in PD diagram by GerryShaw, Wikimedia
GerryShaw, Wikimedia

Tau and alpha-synuclein are proteins that form aggregates which characterize various neurodegenerative disorders including Parkinson’s disease. This feed focuses on the reaction of T lymphocytes in response to tau and alpha-synuclein.

Top 20 most recent papers
bioRxiv

Complement and coagulation cascades are potentially involved in dopaminergic neurodegeneration in alpha-synuclein-based mouse models of Parkinson's disease

bioRxivJanuary 13, 2020
Shi-Xun MaHan Seok Ko
4
Cell Reports

Probiotic Bacillus subtilis Protects against α-Synuclein Aggregation in C. elegans

Cell ReportsJanuary 16, 2020
María Eugenia GoyaMaria Doitsidou
80
30
1
Scientific Reports

The N-terminal Acetylation of α-Synuclein Changes the Affinity for Lipid Membranes but not the Structural Properties of the Bound State

Scientific ReportsJanuary 16, 2020
Matteo RunfolaGiuliana Fusco
3
1
Neuron

Glucocerebrosidase Activity Modulates Neuronal Susceptibility to Pathological α-Synuclein Insult

NeuronJanuary 4, 2020
Michael X HendersonVirginia M Y Lee
40
1
Advances in Experimental Medicine and Biology

Acupuncture Inhibits the Increase in Alpha-Synuclein in Substantia Nigra in an MPTP- Induced Parkinsonism Mouse Model

Advances in Experimental Medicine and BiologyJanuary 2, 2020
Sujung YeoSabina Lim
3
1
Communications Biology

Alpha-synuclein stepwise aggregation reveals features of an early onset mutation in Parkinson's disease

Communications BiologyJanuary 12, 2020
Guilherme A P de Oliveira, Jerson L Silva
JAMA Neurology

Ambroxol for the Treatment of Patients With Parkinson Disease With and Without Glucocerebrosidase Gene Mutations: A Nonrandomized, Noncontrolled Trial

JAMA NeurologyJanuary 14, 2020
Stephen MullinAnthony H V Schapira
71
1
1
Aging

Plasma ubiquitin C-terminal hydrolase L1 levels reflect disease stage and motor severity in Parkinson's disease

AgingJanuary 15, 2020
Adeline Su Lyn NgEng-King Tan
2
1
Molecular Neurodegeneration

Alpha-synuclein-induced mitochondrial dysfunction is mediated via a sirtuin 3-dependent pathway

Molecular NeurodegenerationJanuary 15, 2020
Jae-Hyeon ParkPamela J McLean
7
1
Biochimie

Naturally occurring cinnamic acid derivatives prevent amyloid transformation of alpha-synuclein

BiochimieJanuary 17, 2020
Maria MedvedevaVladimir Muronetz
International Reviews of Immunology

Decoding intrathecal immunoglobulins and B cells in the CNS: their synthesis, function, and regulation

International Reviews of ImmunologyJanuary 14, 2020
Neema Negi, Bimal K Das
2
1
International Journal of Clinical and Experimental Pathology

Alpha-synuclein alterations in red blood cells of peripheral blood after acute ischemic stroke

International Journal of Clinical and Experimental PathologyJanuary 15, 2020
Zimu WuJun Wu
1
International Journal of Clinical and Experimental Pathology

Alpha-synuclein oligomerization increases its effect on promoting NMDA receptor internalization

International Journal of Clinical and Experimental PathologyJanuary 15, 2020
Wenjiao YuShun Yu
1
The Biochemical Journal

Scutellarin Inhibits the Uninduced and Metal-Induced Aggregation of ɑ-Synuclein and Disaggregates Preformed Fibrils: Implications for Parkinson's disease

The Biochemical JournalJanuary 16, 2020
Fatima Kamal Zaidi, Shashank Deep
3
1
Annals of Translational Medicine

Abnormal subpopulations of peripheral blood lymphocytes are involved in Parkinson's disease

Annals of Translational MedicineJanuary 14, 2020
Congcong SunYiming Liu
4
ELife

Inhibition of synucleinopathic seeding by rationally designed inhibitors

ELifeJanuary 3, 2020
Smriti SangwanDavid S Eisenberg
13
1
bioRxiv

Neurodegenerative disease-associated protein aggregates are poor inducers of the heat shock response in neuronal-like cells

bioRxivJanuary 6, 2020
Rebecca San GilHeath Ecroyd
25
Biomaterials Science

Melatonin/polydopamine nanostructures for collective neuroprotection-based Parkinson's disease therapy

Biomaterials ScienceJanuary 9, 2020
Anup K SrivastavaSurajit Karmakar
4
1
ENeuro

Hsc70 Ameliorates the Vesicle Recycling Defects Caused by Excess α-Synuclein at Synapses

ENeuroJanuary 17, 2020
Susan M L BanksJennifer R Morgan
11
Translational Neurodegeneration

δ-secretase in neurodegenerative diseases: mechanisms, regulators and therapeutic opportunities

Translational NeurodegenerationJanuary 9, 2020
Zhentao ZhangKeqiang Ye
1

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