T cells: Antigen Recognition

T cell antigen recognition is mediated by the T cell receptor (TCR), which binds to antigen presented in the context of an MHC molecule on the surface of an antigen-presenting cell. TCR specificity is highly unique as a result of random gene rearrangement. Find the latest research on T cell antigen recognition here.

December 9, 2020

Design and Assessment of Novel Anti-CD30 CARs with Human Antigen-recognition Domains

Human Gene Therapy
Stephanie ChoiJames N Kochenderfer
January 8, 2021
Preprint
Open Access

T cell stiffness is enhanced upon formation of immunological synapse

BioRxiv : the Preprint Server for Biology
P. JungBin Qu
January 9, 2021
Open Access

Immune landscape and prognostic immune-related genes in KRAS-mutant colorectal cancer patients

Journal of Translational Medicine
Jungang LiuWeizhong Tang
December 18, 2020
Preprint
Open Access

Retrograde And Anterograde Transport Of LAT-Vesicles During The Immunological Synapse Formation: Defining The Finely-Tuned Mechanism

BioRxiv : the Preprint Server for Biology
J. J. SaezAndres Ernesto Zucchetti
January 11, 2021
Review
Open Access

How DNA loop extrusion mediated by cohesin enables V(D)J recombination

Current Opinion in Cell Biology
Jan-Michael Peters
December 1, 2020
Open Access

A T-cell reporter platform for high-throughput and reliable investigation of TCR function and biology

Clinical & Translational Immunology
Thomas R MüllerPeter Steinberger
December 20, 2020
Review
Open Access

Combined immunodeficiencies

Jornal de pediatria
Carolina Sanchez ArandaMariana de Gouveia-Pereira Pimentel
December 4, 2020
Open Access

Heterogeneity of T Cells in Atherosclerosis Defined by Single-Cell RNA-Sequencing and Cytometry by Time of Flight

Arteriosclerosis, Thrombosis, and Vascular Biology
Holger Winkels, Dennis Wolf
December 12, 2020

Functionalized Bead Assay to Measure Three-dimensional Traction Forces during T-cell Activation

Nano Letters
Morteza ArameshEnrico Klotzsch
December 22, 2020
Open Access

Kinesin-4 KIF21B limits microtubule growth to allow rapid centrosome polarization in T cells

ELife
Peter Jan HooikaasAnna Akhmanova
December 23, 2020

Transcriptome comparison of isotretinoin-effective and isotretinoin-ineffective severe acne vulgaris patients

Journal of Cosmetic Dermatology
Yuchen JiangYue Zheng
December 16, 2020
Open Access

T cell signaling and Treg dysfunction correlate to disease kinetics in IL-2Rα-KO autoimmune mice

Scientific Reports
Genevieve N MullinsKatrina K Hoyer
December 11, 2020

Identification of Candidate Genes and Pathways in Nonsegmental Vitiligo Using Integrated Bioinformatics Methods

Dermatology : International Journal for Clinical and Investigative Dermatology
Baoyi LiuZhouwei Wu
December 18, 2020
Preprint
Open Access

Probing T-cell response by sequence-based probabilistic modeling

BioRxiv : the Preprint Server for Biology
B. BraviSimona Cocco
December 19, 2020
Open Access

Antigen Specificity Enhances Disease Control by Tregs in Vitiligo

Frontiers in Immunology
Zhussipbek MukhatayevI Caroline Le Poole

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