T cells: Costimulatory Receptors

T cell activation requires engagement of both the T cell receptor and a co-stimulatory molecule. Lack of a co-stimulatory signal can result in T cell anergy, deletion, or immune tolerance. Find the latest research on T cell co-stimulatory receptors here.

September 15, 2020

Successful hematopoietic stem cell transplantation for complete CTLA-4 haploinsufficiency due to a de novo monoallelic 2q33.2-2q33.3 deletion

Clinical Immunology : the Official Journal of the Clinical Immunology Society
Vassilios LougarisAlessandro Plebani
September 10, 2020
Open Access

Mechanisms of allergen-specific immunotherapy and allergen tolerance

Allergology International : Official Journal of the Japanese Society of Allergology
Umut C KucuksezerCezmi A Akdis
September 15, 2020
Open Access

Genomic and immunologic correlates of LAG-3 expression in cancer

Anshuman PandaShridar Ganesan
September 18, 2020
Open Access

Exploratory Pilot Study of Circulating Biomarkers in Metastatic Renal Cell Carcinoma

Ilaria Grazia ZizzariMarianna Nuti
September 14, 2020

Molecular characterisation of HLA class II binding to the LAG-3 T cell co-inhibitory receptor

European Journal of Immunology
Bruce J MacLachlanAndrew Godkin
September 11, 2020
Open Access

Immune checkpoint-related serum proteins and genetic variants predict outcomes of localized prostate cancer, a cohort study

Cancer Immunology, Immunotherapy : CII
Qinchuan WangXifeng Wu
September 10, 2020
Open Access

Immunohistochemical Characterization of Immune Infiltrate in Tumor Microenvironment of Glioblastoma

Journal of Personalized Medicine
Hassan Rahimi KoshkakiAurelia Rughetti
September 18, 2020

Targeting co-stimulatory molecules in autoimmune disease

Nature Reviews. Drug Discovery
Natalie M EdnerLucy S K Walker
September 18, 2020
Open Access

Primary and metastatic breast tumors cross-talk to influence immunotherapy responses

Amanda J OliverClare Y Slaney
September 8, 2020
Open Access

Ly6C defines a subset of memory-like CD27+ γδ T cells with inducible cancer-killing function

BioRxiv : the Preprint Server for Biology
R. WiesheuSeth B Coffelt
September 18, 2020

Reactive Oxidative Species-Modulated Ca2+ Release Regulates β2 Integrin Activation on CD4+ CD28null T Cells of Acute Coronary Syndrome Patients

The Journal of Immunology : Official Journal of the American Association of Immunologists
Yvonne SamstagMathias H Konstandin
September 12, 2020
Open Access

Is There a Role for Immunotherapy in Prostate Cancer?

Alessandro RizzoFrancesco Massari
September 16, 2020

Kindlin-3 loss curbs chronic myeloid leukemia in mice by mobilizing leukemic stem cells from protective bone marrow niches

Proceedings of the National Academy of Sciences of the United States of America
Peter William KrennReinhard Fässler

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