T cells: TNF and Death Receptors

Tumor necrosis factor alpha (TNFa) is an important signaling molecule throughout the immune system. Recent work has focused on the differences in expression and signaling pathways (inflammation vs. tissue regeneration) mediated by TNF receptor 1 (TNFR1) and TNFR2 and the potential for targeting one subtype over the other for therapeutic interventions. Find the latest research on T cells and TNF receptors here.

October 16, 2021

A class II MHC-targeted vaccine elicits immunity against SARS-CoV-2 and its variants.

Proceedings of the National Academy of Sciences of the United States of America
Novalia PisheshaHidde L Ploegh
October 16, 2021
Comment / Editorial

Uncovering the Immunoregulatory Function and Therapeutic Potential of the PD-1/PD-L1 Axis in Cancer.

Cancer Research
Michael R Pitter, Weiping Zou
October 14, 2021

[Changes in the related indicators of bone formation and bone resorption in severely burned rats].

Zhonghua shao shang za zhi = Zhonghua shaoshang zazhi = Chinese journal of burns
X GongW G Xie
October 13, 2021
Open Access

The Positive and Negative Immunoregulatory Role of B7 Family: Promising Novel Targets in Gastric Cancer Treatment.

International Journal of Molecular Sciences
Nadia BolandiBehzad Baradaran
October 13, 2021
Open Access

IL-33 Enhances IFNγ and TNFα Production by Human MAIT Cells: A New Pro-Th1 Effect of IL-33.

International Journal of Molecular Sciences
Mourad AzzoutMaria Leite-de-Moraes
October 13, 2021
Open Access

Intranasal Administration of Codium fragile Polysaccharide Elicits Anti-Cancer Immunity against Lewis Lung Carcinoma.

International Journal of Molecular Sciences
Yuhua WangJun-O Jin
October 11, 2021
Open Access

Targeting Tim-3 in Cancer With Resistance to PD-1/PD-L1 Blockade.

Frontiers in Oncology
Tian Tian, Zhaoming Li
October 11, 2021
Open Access

Immune Checkpoint Inhibitor-Associated Tumor Lysis Syndrome: A Real-World Pharmacovigilance Study.

Frontiers in Pharmacology
Li WangJingli Duan
October 7, 2021

Immunostimulatory effects of targeted thorium-227 conjugates as single agent and in combination with anti-PD-L1 therapy.

Journal for Immunotherapy of Cancer
Pascale LejeuneUrs B Hagemann
October 1, 2021
Open Access

Immune Cell Landscape of Patients With Diabetic Macular Edema by Single-Cell RNA Analysis.

Frontiers in Pharmacology
Pengjuan MaYizhi Liu
October 1, 2021

Single Nucleotide Variant in FAS Associates With Organ Failure and Soluble Fas Cell Surface Death Receptor in Critical Illness.

Critical Care Medicine
Carmen MikacenicMark M Wurfel
September 30, 2021
Open Access

Inflammation plays a causal role in fatigue-like behavior induced by pelvic irradiation in mice.

Brain, Behavior, & Immunity Health
Brian S WolffLeorey N Saligan
September 30, 2021
Open Access

GITR Promotes the Polarization of TFH-Like Cells in Helicobacter pylori-Positive Gastritis.

Frontiers in Immunology
Siqi MingYongjian Wu

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