T Lymphocytes and Neurodegenerative Disorders

Aberrant T cell activity is known to mediate considerable damage in a variety of disease states. The immune system has been recognized to contribute to the development of neurodegenerative disorders. It is therefore important to identify the characteristics of T cells involved in the pathogenesis of neurodegenerative diseases. Discover the latest research on T cells and neurodegeneration here.

May 27, 2020

Common germline variants of the human APOE gene modulate melanoma progression and survival

Nature Medicine
Benjamin N OstendorfSohail F Tavazoie
August 1, 2020
Open Access

Midbrain Dopaminergic Neuron Development at the Single Cell Level: In vivo and in Stem Cells

Frontiers in Cell and Developmental Biology
Emilía Sif Ásgrímsdóttir, Ernest Arenas
August 3, 2020

CD8+ T cells are increased in the subventricular zone with physiological and pathological aging

Aging Cell
Manuel Moreno-ValladaresAnder Matheu
July 19, 2020
Open Access

Neuroinflammation is associated with infiltration of T cells in Lewy body disease and α-synuclein transgenic models

Journal of Neuroinflammation
Michiyo IbaEliezer Masliah
June 17, 2020

Microglia-released leukotriene B4 promotes neutrophil infiltration and microglial activation following intracerebral hemorrhage

International Immunopharmacology
Masanori HijiokaYoshihisa Kitamura
July 22, 2020

Resveratrol ameliorates thymus senescence changes in D-galactose induced mice

Microbiology and Immunology
Ting-Ting WeiYu-Rong Chai
June 7, 2020
Open Access

Harnessing regulatory T cell neuroprotective activities for treatment of neurodegenerative disorders

Molecular Neurodegeneration
Jatin MachhiHoward E Gendelman
July 16, 2020

Fast and synchronized fluctuations of cortical actin negatively correlate with nucleoli liquid-liquid phase separation in T cells

European Biophysics Journal : EBJ
Ishay WohlEilon Sherman
June 18, 2020
Open Access

Exploring the Toxicology of Depleted Uranium with Caenorhabditis elegans

ACS Omega
Meiling LuXiaohui Wang
July 21, 2020
Open Access

Quantifying lymphocyte vacuolization serves as a measure of CLN3 disease severity

JIMD Reports
Willemijn F E KuperPeter M van Hasselt
June 25, 2020

Astrocyte-Derived Exosomes in an iPSC Model of Bipolar Disorder

Advances in Neurobiology
D AttiliK S O'Shea
July 29, 2020

Reciprocal Interplay Between Astrocytes and CD4+ Cells Affects Blood-Brain Barrier and Neuronal Function in Response to β Amyloid

Frontiers in Molecular Neuroscience
Simona Federica SpampinatoMaria Angela Sortino
June 11, 2020
Open Access

Pharmacological inhibition of carnitine palmitoyl transferase 1 inhibits and reverses experimental autoimmune encephalitis in rodents

PloS One
Anne Skøttrup MørkholtJohn Dirk Vestergaard Nieland
July 3, 2020
Open Access

Peripheral and Central Nervous System Immune Response Crosstalk in Amyotrophic Lateral Sclerosis

Frontiers in Neuroscience
Zhouyang LiuChuansheng Zhao
May 25, 2020

Targeting macrophages by an aza-anthrapyrazole to ameliorate experimental autoimmune encephalomyelitis

Multiple Sclerosis and Related Disorders
Boren LinBoyd M Koffman

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