T Lymphocytes & Neurodegenerative Disorders

Aberrant T cell activity is known to mediate considerable damage in a variety of disease states, and the immune system has been recognized to contribute to the development of neurodegenerative disorders. It is therefore important to identify the characteristics of T cells involved in the pathogenesis of neurodegenerative diseases. Discover the latest research on T cells and neurodegeneration here.

December 6, 2021

Alterations in T-Cell Transcription Factors and Cytokine Gene Expression in Late-Onset Alzheimer's Disease.

Journal of Alzheimer's Disease : JAD
Masoud NeshanGhasem Ahangari
December 4, 2021

CD4+ T Cells Contribute to Neurodegeneration in Lewy Body Dementia.

Movement Disorders : Official Journal of the Movement Disorder Society
Alexandra Zirra, Brook Huxford
December 2, 2021

CSF-Derived CD4+ T-Cell Diversity Is Reduced in Patients With Alzheimer Clinical Syndrome.

Neurology. Neuroimmunology and Neuroinflammation
Chaitanya JoshiNancy Monson
November 29, 2021

Impact of T cells on neurodegeneration in anti-GAD65 limbic encephalitis.

Annals of Clinical and Translational Neurology
Andre DikNico Melzer
November 26, 2021

Repeated administration of 2-hydroxypropyl-β-cyclodextrin (HPβCD) attenuates the chronic inflammatory response to experimental stroke.

The Journal of Neuroscience : the Official Journal of the Society for Neuroscience
Danielle A BecktelKristian P Doyle
November 23, 2021
Review
Open Access

Alpha-Synuclein Induced Immune Cells Activation and Associated Therapy in Parkinson's Disease.

Frontiers in Aging Neuroscience
Ruichen Su, Tian Zhou
November 21, 2021
Open Access

CD4+ effector T cells accelerate Alzheimer's disease in mice.

Journal of Neuroinflammation
Jatin MachhiHoward E Gendelman
November 19, 2021

Neurodegenerative disease in association with sexual transmission of human T-cell lymphotropic virus type 2 subtype b in Argentina.

Transactions of the Royal Society of Tropical Medicine and Hygiene
Sebastián BlancoSandra Verónica Gallego
November 17, 2021

Non-canonical roles of autophagy proteins in endocytosis and exocytosis.

Biochemical Society Transactions
Christian Münz
November 15, 2021
Open Access

Administration of anti-ERMAP antibody ameliorates Alzheimer's disease in mice.

Journal of Neuroinflammation
Haiyan LiuLaijun Lai
November 13, 2021

Immunoprofiling of fresh HAM/TSP blood samples shows altered innate cell responsiveness.

PLoS Neglected Tropical Diseases
Brenda RocamondeHélène Dutartre
November 13, 2021
Open Access

Following the Clues: Usefulness of Biomarkers of Neuroinflammation and Neurodegeneration in the Investigation of HTLV-1-Associated Myelopathy Progression.

Frontiers in Immunology
Flávia Dos Santos SouzaOtávio Melo Espíndola
November 11, 2021
Review

The role of lymphocytes in neonatal encephalopathy.

Brain, Behavior, & Immunity Health
Ashanty M MeloEleanor J Molloy
November 10, 2021
Open Access

Effect of exposure to low doses of ozone on interleukin 17A expression during progressive neurodegeneration in the rat hippocampus.

Neurología
H Solleiro-VillavicencioS Rivas-Arancibia
November 1, 2021

Delivery strategies for cell-based therapies in the brain: overcoming multiple barriers.

Drug Delivery and Translational Research
Olivia M TurkJennifer M Munson
November 2, 2021
Review
Open Access

Galectins and Their Ligand Glycoconjugates in the Central Nervous System Under Physiological and Pathological Conditions.

Frontiers in Neuroanatomy
Junko Nio-Kobayashi, Tetsuya Itabashi

Sign up to follow this feed and discover related papers.

Related Feeds

3D Cellular Models of Brain and Neurodegeneration

Brain organoids are three-dimensional in vitro cellular models of the brain that can recapitulate many processes such as the neurodevelopment. In addition, these organoids can be combined with other cell types, such as neurons and astrocytes to study their interactions in assembloids. Disease processes can also be modeled by induced pluripotent stem cell-derived organoids and assembloids from patients with neurodegenerative disorders. Discover the latest research on the models here.

ALS & FTD: TDP-43

TAR DNA-binding protein 43 (TDP-43) is a pathological protein identified in sporadic Amyotrophic Lateral Sclerosis (ALS) and Frontotemporal Dementia (FTD). Here are the latest discoveries pertaining to TDP-43 and these diseases.

ALS: Genetics

Amyotrophic Lateral Sclerosis (ALS) is a progressive neurodegenerative disorder characterized by muscle weakness. ALS is a genetically heterogeneous disorder with several causative genes. Here are the latest discoveries pertaining to the genetics of this disease.

ALS: Pathogenic Mechanisms

Amyotrophic Lateral Sclerosis is a progressive neurodegenerative disorder characterized by muscle weakness. Here is the latest research investigating pathogenic mechanisms that underlie this genetically heterogeneous disorder.

ALS: Phenotypes

Amyotrophic Lateral Sclerosis (ALS) is a neurodegenerative disorder characterized phenotypically by progressive muscle weakness. Clinical phenotypes of ALS can be classified based on the pattern, level, and area of onset (e.g. bulbar, cervical, lumbar). Here is the latest research investigating phenotypes of ALS.

ALS: Prions

Prions are misfolded proteins which characterize several fatal neurodegenerative diseases. Prion-like mechanisms are associated with the pathogenesis of Amyotrophic Lateral Sclerosis (ALS). Here is the latest research on ALS and prions.

ALS: Stress Granules

Amyotrophic Lateral Sclerosis (ALS) is a neurodegenerative disease characterized by cytoplasmic protein aggregates within motor neurons. TDP-43 is an ALS-linked protein that is known to regulate splicing and storage of specific mRNAs into stress granules, which have been implicated in formation of ALS protein aggregates. Here is the latest research in this field.

ALS: Therapies

Amyotrophic Lateral Sclerosis (ALS) is associated with the death of neurons that control voluntary muscles. This feed followes the latest research into therapies for this progressive neurodegenerative disease.

Age-related Dementia

Dementias are a group of conditions, including Alzheimer's disease, vascular dementia, and frontotemporal dementia, characterized by deficiencies in cognitive abilities. Age-related dementia refers to dementias that occur in older individuals, usually 60+ years old, in contrast to early-onset dementia. Follow the latest research on age-related dementia here.

Alexander Disease

Alexander disease is a rare leukodystrophy caused by mutations in the astrocyte-specific intermediate filament protein glial fibrillary acidic protein (GFAP). Here is the latest research on this disease.

© 2021 Meta ULC. All rights reserved
/feed-previews/t-lymphocytes-neurodegenerative/908b21a8-f39a-4fc3-ab2f-dba4338bdb74