TALEs and TALENs

Transcription activator-like effectors (TALEs) and TALE nucleases (TALENs) enable gene editing by targeting specific DNA sequences in the genome. Here is the latest research.

November 18, 2020
Review
Open Access

BH3 Mimetics for the Treatment of B-Cell Malignancies-Insights and Lessons from the Clinic

Cancers
Victor S LinRachel Thijssen
January 9, 2021
Open Access

Draft Genome Sequences of 284 Xanthomonas citri pv. citri Strains Causing Asiatic Citrus Canker

Microbiology Resource Announcements
Damien RichardOlivier Pruvost
January 15, 2021
Review
Open Access

Designer nucleases to treat malignant cancers driven by viral oncogenes

Virology Journal
Tristan A Scott, Kevin V Morris
January 20, 2021
Open Access

Consequences of adaptation of TAL effectors on host susceptibility to Xanthomonas

PLoS Genetics
Doron Teper, Nian Wang
January 2, 2021
Open Access

Disruption of Abcc6 Transporter in Zebrafish Causes Ocular Calcification and Cardiac Fibrosis

International Journal of Molecular Sciences
Jianjian SunTao P Zhong
December 17, 2020
Open Access

Functional Analysis of Adipokinetic Hormone Signaling in Bombyx mori

Cells
Hana SehadovaMichal Zurovec
December 12, 2020
Open Access

An efficient and precise method for generating knockout cell lines based on CRISPR-Cas9 system

Engineering in Life Sciences
Xibin LuWei Huang
January 12, 2021
Correction
Open Access

Erratum to: Regulation of IL12B Expression in Human Macrophages by TALEN-mediated Epigenome Editing

Current Medical Science
Meng ChenMei Ye
November 20, 2020
Review

Novel insights into gene therapy in the cornea

Experimental Eye Research
Rajiv R MohanNishant R Sinha
November 26, 2020
Review
Open Access

Genome Editing by CRISPR-Cas: A Game Change in the Genetic Manipulation of Chlamydomonas

Life
Manel GhribiIsabel Desgagné-Penix
December 29, 2020
Open Access

Detailed genetic and functional analysis of the hDMDdel52/mdx mouse model

PloS One
Alper YavasNicole Datson
December 31, 2020
Open Access

Elimination of Mutant mtDNA by an Optimized mpTALEN Restores Differentiation Capacities of Heteroplasmic MELAS-iPSCs

Molecular Therapy. Methods & Clinical Development
Naoki YahataRyuji Hata
January 15, 2021
Preprint
Open Access

KLF14 Inhibits Renal Mesangial Cell Proliferation by Promoting Btg2 Gene Expression

ResearchSquare
Xiaoyuan WuXueyuan Bai
January 21, 2021

Improving a Quantitative Trait in Rice by Multigene Editing with CRISPR-Cas9.

Methods in Molecular Biology
Yesuf Teslim YimamYong Zhang
January 6, 2021

Combinatorial Strategies for Long-term Control of HIV Infection

AIDS Reviews
Daekee KwonKyung-Sun Kang
December 12, 2020
Open Access

Cell-Based Therapy for Canavan Disease Using Human iPSC-Derived NPCs and OPCs

Advanced Science
Lizhao FengYanhong Shi
November 19, 2020

Axial Skeletal Malformations in Genetically Modified Xenopus laevis and Xenopus tropicalis

Comparative Medicine
Anne L ZlatowSherril L Green
December 17, 2020
Preprint
Open Access

Understanding Thioamitide Biosynthesis Using Pathway Engineering and Untargeted Metabolomics

BioRxiv : the Preprint Server for Biology
T. H. EylesAndrew W Truman
December 12, 2020
Open Access

Time-calibrated genomic evolution of a monomorphic bacterium during its establishment as an endemic crop pathogen

Molecular Ecology
Damien RichardPierre Lefeuvre

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